enzyme enhancement
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Potent chemical chaperone compounds for GM1-gangliosidosis: N-substituted (+)-conduramine F-4 derivatives

MedChemComm ◽  
2015 ◽  
Vol 6 (2) ◽  
pp. 306-310 ◽  
Author(s):  
Shinichi Kuno ◽  
Katsumi Higaki ◽  
Atsushi Takahashi ◽  
Eiji Nanba ◽  
Seiichiro Ogawa
Keyword(s):  
Inhibitory Activity ◽  
Gm1 Gangliosidosis ◽  
Chemical Chaperone ◽  
Chemical Chaperones ◽  
Enzyme Enhancement

The development of chemical chaperones to decrease the inhibitory activity while increasing the enzyme enhancement activity is described.

Pharmacological chaperones for enzyme enhancement therapy in genetic diseases

2013 ◽  
Vol 2 (1) ◽  
pp. 109-124 ◽  
Author(s):  
Juan Aymami ◽  
Xavier Barril ◽  
Laura Rodríguez-Pascau ◽  
Marc Martinell
Keyword(s):  
Genetic Diseases ◽  
Pharmacological Chaperones ◽  
Enzyme Enhancement

Traditional medicine Taeeumjowitangkagambang exerts antiobesity and hypolipidemic effects via antioxidant enzyme enhancement

2010 ◽  
Vol 24 (11) ◽  
pp. 1700-1709 ◽  
Author(s):  
Cheol-Hwan Park ◽  
Soo-Jin Jeong ◽  
Hyo-Jeong Lee ◽  
Eun-Ok Lee ◽  
Hyunsu Bae ◽  
...  
Keyword(s):  
Traditional Medicine ◽  
Antioxidant Enzyme ◽  
Enzyme Enhancement

135. Identification of pyrimethamine derivatives showing improved enzyme enhancement efficacy towards mutant Hex A

2010 ◽  
Vol 99 (2) ◽  
pp. S36
Author(s):  
Michael Tropak ◽  
Sayuri Yonekawa ◽  
Jianmin Zhang ◽  
Kam Ho ◽  
Virender Aulakh ◽  
...  
Keyword(s):  
Enzyme Enhancement

scholarly journals Identification and Characterization of Ambroxol as an Enzyme Enhancement Agent for Gaucher Disease

2009 ◽  
Vol 284 (35) ◽  
pp. 23502-23516 ◽  
Author(s):  
Gustavo H. B. Maegawa ◽  
Michael B. Tropak ◽  
Justin D. Buttner ◽  
Brigitte A. Rigat ◽  
Maria Fuller ◽  
...  
Keyword(s):  
Gaucher Disease ◽  
Identification And Characterization ◽  
Enzyme Enhancement

65. Identification of Ambroxol as a potential enzyme enhancement-agent for Gaucher disease

2008 ◽  
Vol 93 (2) ◽  
pp. 30
Author(s):  
Don Mahuran ◽  
Gustavo Maegawa ◽  
Michael Tropak ◽  
Justin Butner ◽  
Gregory Kornhaber ◽  
...  
Keyword(s):  
Gaucher Disease ◽  
Enzyme Enhancement

scholarly journals Enzyme enhancement activity of N-octyl-β-valienamine on β-glucosidase mutants associated with Gaucher disease

2007 ◽  
Vol 1772 (5) ◽  
pp. 587-596 ◽  
Author(s):  
Ke Lei ◽  
Haruaki Ninomiya ◽  
Michitaka Suzuki ◽  
Takehiko Inoue ◽  
Miwa Sawa ◽  
...  
Keyword(s):  
Gaucher Disease ◽  
Enzyme Enhancement
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