promoter study
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2003 ◽  
Vol 185 (17) ◽  
pp. 5314-5319 ◽  
Author(s):  
Daniel Aubert ◽  
Thierry Naas ◽  
Patrice Nordmann

ABSTRACT The integron-borne bla VEB-1 gene encodes an extended-spectrum β-lactamase. This gene was associated mostly with IS1999 and rarely with an additional IS2000 element in Pseudomonas aeruginosa isolates from Thailand, whereas IS1999 was only very rarely associated with bla VEB-1 in Enterobacteriaceae. Expression experiments and promoter study identified promoter sequences in IS1999 that increased the expression of VEB-1 in P. aeruginosa.


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