Thermal welding of polymeric biomaterials: Development of a novel device for temperature controlled local application

We present a thermal processing device, equipped for local heating and welding of biomaterials, e.g. electrospun nonwovens or polymer films. Depending on the application and choice of materials, we aim to determine appropriate processing parameters for permanent and non-permanent welds. Due to the modular device structure, applicationspecific heating tools can be used. Process temperature up to 250 °C is feasible. In this concept study, a welding tool with interchangeable small-size heating tips of different geometric shapes were investigated regarding their suitability for welding of polycarbonate urethane based silicone elastomer nonwovens. Generated welds were examined by imaging techniques and tensile testing. Regardless of the tip shape, welds were generated withstanding forces up to 3.0 N and 4.3 N for tensile and shear loading, respectively.

Thermophysical properties of the TiAl-2Cr-2Nb alloy in the liquid phase measured with an electromagnetic levitation device on board the International Space Station, ISS-EML

Thermophysical properties of the γ-TiAl alloy Ti-48Al-2Cr-2Ni in the liquid phase were investigated with a containerless electromagnetic processing device on board the International Space Station. Containerless processing is warranted by the high liquidus temperature T liq = 1 776 K and the high dissolution reactivity in the liquid phase. Thermophysical properties investigated include the surface tension and viscosity, density, specific heat capacity and the electrical resistivity. The experiments were supported by magnetohydrodynamic fluid flow calculations. The Ti-48Al-2Cr-2Ni alloy could be stably processed over extended times in the stable and undercooled liquid phase and exhibited an exceptional degree of undercooling before solidification. Experimental processes and thermophysical properties so obtained will be described. The experiments demonstrate the broad experimental capabilities of the electromagnetic processing facility on the International Space Station for thermophysical investigations in the liquid phase of metallic alloys not achievable by other methods.

The Gibco™ CTS™ Rotea™ system story—a case study of industry-academia collaboration

The Gibco™ CTS™ Rotea™ Counterflow Centrifugation System is an automated cell processing device developed for manufacturing cell therapy products. The developer (Scinogy Pty Ltd) collaborated with Thermo Fisher Scientific to successfully launch the product in late 2020, completing product development from concept to international sales in <3years. This article describes the origin story of the Rotea system and how a chance meeting between a co-inventor of the Rotea system and an academic cell biologist took the invention from a garage workshop to the world stage. We describe the contribution of academic research to the innovation value chain and importance of academic institutions being industry-ready to support such collaborations.

Light-weight Electrophysiology Hardware and Software Platform for Cloud-Based Neural Recording Experiments

Objective. Neural activity represents a functional readout of neurons that is increasingly important to monitor in a wide range of experiments. Extracellular recordings have emerged as a powerful technique for measuring neural activity because these methods do not lead to the destruction or degradation of the cells being measured. Current approaches to electrophysiology have a low throughput of experiments due to manual supervision and expensive equipment. This bottleneck limits broader inferences that can be achieved with numerous long-term recorded samples. Approach. We developed Piphys, an inexpensive open source neurophysiological recording platform that consists of both hardware and software. It is easily accessed and controlled via a standard web interface through Internet of Things (IoT) protocols. Main Results. We used a Raspberry Pi as the primary processing device and Intan bioamplifier. We designed a hardware expansion circuit board and software to enable voltage sampling and user interaction. This standalone system was validated with primary human neurons, showing reliability in collecting real-time neural activity. Significance. The hardware modules and cloud software allow for remote control of neural recording experiments as well as horizontal scalability, enabling long-term observations of development, organization, and neural activity at scale.

CONCEPTUAL DESIGN OF BOMB DETECTOR AS ANTICIPATION OF TERRORISM THREAT TO PUBLIC SERVICES

<p>Acts of terrorism are crimes and serious violations of human rights, also the threat of violence that can cause mass casualties and destruction of vital strategic objects. This is an urgent threat that needs to be prepared by designing a bomb detector conceptual design as anticipation of the threat of terrorism in public services. This study aims to obtain operational requirements and conceptual design of bomb detectors as detection of terrorism threats in public services. This study uses a mixed-method with a systems engineering approach and a life cycle model to produce a technological design. The results of operational requirements are sensors, standards, artificial intelligence, integration capability, reliability, calibration mode, portable, and easy to maintain. The configuration design is divided into three stages, namely, 1) sensors including a camera security surveillance system vector image, metal detectors, explosive detectors, and A-jamming; 2) as a processing device, processes an order with the help of an artificial intelligence system; and 3) a security computer (surveillance), early warning, and mobile information to provide information to related agencies, especially the anti-terror unit.</p>

An integrated scheduling algorithm for multi-device-processes with the strategy of exchanging adjacent parallel processes of the same device

At present, Multi-Devices-Process Integrated Scheduling Algorithm with Time-Selective Strategy for Process Sequence (MISATPS) is an advanced algorithm in the field of integrated scheduling with multi-devices-process problems. This algorithm ignores the influence of the pre-process on the post-process when solving the multi-devices-process integrated scheduling problem, which leads to the problem of poor closeness between serial processes and poor parallelism between parallel processes. This paper points out that there is no restriction of scheduling sequence between parallel processes on the same processing device. It can be scheduled flexibly of the sequence between parallel processes of the same device. Therefore, based on the scheduling scheme of MISATPS, the algorithm is improved by applying the interchange strategy and the interchange adjustment strategy of multi-device adjacent parallel process. In this way, the influence of the pre-process on the post-process is avoided, the compactness of the serial process and the parallelism of the parallel process are improved, and the scheduling result is optimized.

An Integrated Scheduling Algorithm for Multi-Device-Processes with the Strategy of Exchanging Adjacent Parallel Processes of The Same Device

The current integrated scheduling algorithm ignores the influence of the pre-process on the post-process when solving the multi-device-process integrated scheduling problem, which leads to the problem of poor tightness between serial processes and low parallelism between parallel processes. This paper points out that there is no restriction of scheduling sequence between adjacent parallel processes on the same processing device, and the scheduling sequence between parallel processes on the same device can be flexibly processed to optimize the scheduling results, on the basis of the current algorithm scheduling scheme, this paper proposes the application of multi-device adjacent parallel process interchange strategy and multi-device adjacent parallel process interchange adjustment strategy, which avoid the influence of the pre-process on the post-process, improves the compactness of the serial process and the parallelism of the parallel process, and optimizes the scheduling results.