Uncommon anatomical sites and anatomopathological presentations of lymphoma in dogs

ABSTRACT: Lymphomas are the tumors most frequently associated with the death or euthanasia of dogs in most parts of the world. In dogs, they almost always occur as disseminated (multicentric lymphoma), gastrointestinal (alimentary lymphoma), or nodal mediastinal (mediastinal lymphoma) diseases. However, other uncommon presentations can occasionally occur. This study aimed to establish the prevalence of these unusual types of lymphoma and demonstrate to veterinary pathologists how they present pathologically. From a total of 100 cases of lymphoma in dogs diagnosed between 1965 and 2017, 16 cases (16/100) were considered by us as non-traditional presentations of the disease: follicular lymphoma, (5/100), peripheral T-cell lymphoma, NOS (2/100), angiocentric lymphoma (2/100), intravascular large T-cell lymphoma (2/100), lymphomatoid granulomatosis (1/100), anaplastic large-cell lymphoma (1/100), hepatosplenic T-cell lymphoma (1/100), and chronic small B-cell lymphocytic lymphoma, intermediate type (1/100). We hope that the results presented here can help veterinary pathologists to recognize such cases of “atypical lymphoma” in their diagnostic routines.

A Case of Cutaneous T-Cell Lymphoma with Nodular Skin Lesions, Third Nerve Palsy and Peripheral Vascular Disease: Can It Be a Case of Angiocentric Lymphoma?

Angiocentric lymphoma is a subtype of cutaneous T-cell lymphoma, characterized by occlusion of vessels by lymphoid infiltrate. Here, we report a case of biopsy confirmed cutaneous T-cell lymphoma who presented with third cranial nerve palsy, peripheral vascular disease and nodular skin lesions in the right thigh. All these findings of this case can be explained by mechanism of vascular infiltration and tissue destruction in angiocentric lymphoma which is a rare disorder.Birdem Med J 2016; 6(1): 40-42