Sex differences regarding the impact of a standardized adaptation session in Colombian patients with obstructive sleep apnea and poor adherence to positive airway pressure devices

Introduction: Positive airway pressure (PAP) is the most effective treatment for obstructive sleep apnea (OSA) but adherence is poor. The Sleep-disordered breathing clinic of Fundación Neumológica Colombiana (FNC) has a standardized adaptation session (SAS) aimed at patients with difficulties in using PAP devices. Objective: To evaluate the impact of a SAS in short-term adherence to PAP therapy in patients with OSA and to determine sex differences. Materials and methods: Before-after single cohort study conducted in 40 people aged ≥ 18 years with an AHI ≥ 15/hour and treated at the FNC, Bogotá D.C. (Colombia) between 2015 and 2017, and who attended a SAS due to poor adherence to PAP therapy (defined as <4 hours use in 70% of nights). Data on the hours of use of the PAP device and the % of days in which it was used >4 hours were recorded before and after the intervention to evaluate changes in patients’ adherence. Descriptive statistics were used for data analysis. The paired samples t-test was used for the comparison of variables before and after the intervention. Results: A significant increase was observed in the PAP device use (1.8 hours, 95%CI: 1.3-2.3; p<0.001) and in the % of days its use was >4 hours (35.6%, 95%CI: 26.0-45.3; p<0.001); in men the increase was greater in both cases (2.3 hours, 95%CI: 1.7-2.9; p=0.029 and 47.8%, 95%CI: 32.9-62.8; p=0.029). Conclusion: The SAS offered by the FNC, which includes education strategies and the identification and solving of barriers hindering the use of PAP devices, significantly increased the hours of use of the device and the % of days in which it was used more than 4 hours in the study population, in particular in men.

See What You Feel: A Crossmodal Tool for Measuring Haptic Size Illusions

The purpose of this research is to present the employment of a simple-to-use crossmodal method for measuring haptic size illusions. The method, that we call See what you feel, was tested by employing Uznadze’s classic haptic aftereffect in which two spheres physically identical (test spheres) appear different in size after that the hands holding them underwent an adaptation session with other two spheres (adapting spheres), one bigger and the other smaller than the two test spheres. To measure the entity of the illusion, a three-dimensional visual scale was created and participants were asked to find on it the spheres that corresponded in size to the spheres they were holding in their hands out of sight. The method, tested on 160 right-handed participants, is robust and easily understood by participants.

The extent of interlimb transfer following adaptation to a novel visuomotor condition does not depend on awareness of the condition

There is a controversy in the literature as to whether transfer of motor learning across the arms occurs because of an individual's cognitive awareness of the learned condition. The purpose of this study was to test whether the extent of interlimb transfer following adaptation to a novel visuomotor rotation with one arm, as well as the rate of learning acquired by the other arm, would vary depending on the subjects' awareness of the rotation condition. Awareness of the condition was varied by employing three experimental conditions. In one condition, visual rotation of the display up to 32° was gradually introduced to minimize the subjects' awareness of the rotation during targeted reaching movement. In another condition, the 32° rotation was abruptly introduced from the beginning of the adaptation session. Finally, the subjects were informed regarding the rotation prior to the adaptation session. After adaptation with the left arm under the three conditions, subjects performed reaching movement with the right arm under the same 32° rotation condition. Our results showed that the amount of initial transfer, and also the changes in performance with the right arm, did not vary significantly across the three conditions. This finding suggests that interlimb transfer of visuomotor adaptation does not occur based on an individual's awareness of the manipulation, but rather as a result of implicit generalization of the obtained visuomotor transformation across the arms.