ON THE POSSIBILITIES OF REHABILITATION OF PATIENTS WITH CHRONIC DERMATOSES AND DISEASES OF THE GENITAL AREA IN THE SOUTH OF UKRAINE – KHERSON REGION

The article provides an example of the effective introduction of comprehensive rehabilitation therapy for patients with common and severe skin diseases (psoriasis, atopic dermatitis, eczema, lichen planus, and others), arthropathy of various origins and diseases of the genital area. The Center has been operating since 2018 as a subdivision of the Kherson Regional Skin and Venereal Diseases Dispensary of the Kherson Regional Council of Kherson, and later on, the public organization «Kherson Psoriasis Association» opened the «Aquaderm» Dermatological Center here. Materials and methods. The center is provided with modern equipment (3 types of bathtubs – Chirana, hydromassage, whirlpool; ultraviolet irradiation apparatus «Psorolight 100-6»). Physiotherapeutic procedures are used, consisting in the treatment with mineral waters, as well as with the therapeutic mud of Lake Solyanoye(Kherson region). Light therapy and climatotherapy are used. Patients undergo a set of laboratory tests before prescribing therapy and during treatment. Discussion of the findings. The data on the treatment of patients at the «Aquaderm» institution in 2018–2019 and the first half of 2020 are presented. A total of 5551 patients were treated during the reporting period and 164601 physiotherapeutic procedures were performed, what indicate that the types of rehabilitation treatment used are effective. The center attracts patients from different regions of Ukraine and enjoys the support of the Kherson Regional State Administration.

Nitridation Reaction of Titanium Powders by 2.45 GHz Multimode Microwave Irradiation using a SiC Susceptor in Atmospheric Conditions

A titanium nitride (TiN) coating using microwaves can be accomplished in air, and satisfies the required conditions of an on-demand TiN coating process. However, the coating mechanism using microwaves is not completely clear. In this study, to understand the detailed mechanism of microwave titanium nitridation in air, the quantity of nitrogen and oxygen in reacted TiN powder has been investigated by an inert melting method. Titanium powders were irradiated with microwaves by a multi-mode type 2.45 GHz microwave irradiation apparatus, while also being held at various temperatures for two different dwell times. X-ray diffraction (XRD) results revealed that nitridation of the powder progressed with increasing process temperature, and the nitridation corresponds to the powder color after microwave irradiation. The nitrogen contents of the samples increased with increasing processing temperature and dwell time, unlike oxygen. It is postulated that the reaction of convected air with titanium is a key role to control nitridation in this system.

Swelling characterization of photo-cross-linked gelatin methacrylate spherical microgels for bioencapsulation

The swelling behavior of biocompatible and biodegradable polymers is important for the delivery and release of cells and drugs in biomedical applications. This study reported the swelling characteristics of photo-cross-linked gelatin methacrylate (GelMa) spherical microgels. Spherical microgels were generated in a microfluidic system consisting of a co-axial flow-focusing device for microdroplet generation and an ultraviolet (UV) irradiation apparatus for polymerization. At a low flow rate ratio (<0.14), the 9 wt.% GelMa spherical microgels were smaller than the 6 wt.% ones. In contrast, at a high flow rate ratio (>0.14), the results were reversed. Overall, a proportional relationship was observed between the flow rate ratio and the droplet size. The increased GelMa concentration improved the mechanical properties and increased the swelling ratios. The possibility of bioencapsulation was demonstrated, with good viability of 3T3 cells encapsulated in the spherical microgels.

Time dose reciprocity in UV disinfection of water

The microbicidal effect of UV light depends on the dose in both, disinfection processes and natural inactivation by the sunlight in surface water. Deviations of the time dose reciprocity are well known from chemical water disinfection whereas no data are available about this effect in UV inactivation in water. In a previous study we found that the UV inactivation behaviour of yeast strains does not follow the time dose reciprocity, insofar that longer exposure led to higher reduction of cultivable cells. In contrast, an earlier study about E coli B/r claimed a higher inactivation with single exposure compared with fractionated UV irradiation. To investigate this question we selected water-relevant microorganisms and studied their UV inactivation behaviour (253.7nm) by means of a specially designed UV irradiation apparatus (a) under standard irradiation conditions (2W/m2) and (b) with three levels of UV dose rate (2, 0.2 and 0.02W/m2). The test organisms were (i) three E coli strains (ATCC 25922, ATCC 11229 and an isolate from sewage) representing the routinely used faecal indicator, (ii) three bacterial viruses (MS2, ϕX174 and B40-8) proposed as indicators for viral contamination in water and (iii) spores of Bacillus subtilis because of their use as a biodosimeter in prototype testing of commercial UV plants for drinking water disinfection. We found, under standard inactivation conditions, that the E coli strains and phage ϕX174 are most UV susceptible, followed by B40-8 and finally MS2 and bacterial spores. The dose protraction experiments revealed for the E coli strains a higher inactivation with high dose rates compared to low dose rates at the same UV doses (difference of about 1 log10 at 80-100J/m2). The other test organisms did not deviate from the time dose reciprocity in the proven range of dose.