Synthesis and characterization of new mixed ligand complexes of Zn (II) and Hg (II) with dithiocarbamate and phosphines

Complexes of the type [M (Et2DTC)2]2 [M= Zn(1) or Hg(2)] were prepared from the reaction of mercury acetate or zinc acetate with sodium diethyldithiocarbamate trihydrate (NaEt2DTC.3H2O) in (1:2) molar ratio (metal: ligand) in mixture of MeOH and H2O as a solvent. Treatment equal molar of (1) or (2) with diphosphine ligands {where diphos: bis (diphenylphosphino) methane (dppm), 1,2-bis (diphenylphosphino) ethane (dppe) and 1,3-Bis (diphenylphosphino) propane (dppp)} afforded complexes of the type [Zn(Et2DTC)2(dppeO)] (3); [Zn(Et2DTC)2(dpppS)] (4a); [Zn(Et2DTC)2(dppp)] (4b); [Hg(Et2DTC)2(dppm)] (6a); [Hg(Et2DTC)2(µ-dppm)]2(6b); [Hg(Et2DTC)2(dppe)](7) and [Hg(Et2DTC)2(dppp)](8), or with two moles of triphenylphosphine (PPh3) afforded a complexes of the type [M(κ1-Et2DTC)2(PPh3)2] (5a, 9a) and [M(κ2-Et2DTC)2(PPh3)2] (5b, 9b) {M= Zn, Hg}. The prepared complexes were fully characterized by different technics such as IR, NMR (1H and 31P) spectroscopy, elemental analysis, and molar conductivity. Characterization data showed that the (Et2DTC) ligand in all of the prepared complexes was coordinated with metal through the sulfur atoms of CSS- group. The geometry of the complexes (1-9) were tetrahedral around the Zn(II) and Hg(II) ions, except isomers 5b and 9b are octahedral geometry. . http://dx.doi.org/10.25130/tjps.25.2020.011

New Salicylanilide-Hg(II) complexes with phosphine ligands, Synthesis and spectroscopic investigation

A new complex of the type [Hg(k2-Saln)2] (1) was prepared from the reaction of mercury acetate and salicylanilide (HSaln) in (1:2) molar ratio EtOH as a solvent with presence an Et3N as a base. Treatment of complex (1) with diphosphine {where diphos: dppe, dppp, dppb dppf and dppmS2} in 1:1) (complex: diphos) molar ratio afforded a complexes of the types [Hg(k1-Saln)2(diphos)] (2-6),where as a complexes of the types [Hg(k1-Saln)2(phos)2] (7,8) when treatment of complex(1) with two moles of monophosphine (PPh3 or SPPh3). The prepared complexes were fully characterization by many technical such as elemental analysis, molar conductivity, infrared spectroscopy, and nuclear magnetic resonance (1H and 31P). In complex (1) the (Saln-) was bonded as bidentate chelating ligand through the oxygen atoms of the carbonyl and deprotonated hydroxyl group, whereas bonded as monodentate ligand through the oxygen atom of deprotonated hydroxyl group in all other complexes (2-8). The geometry of the complexes (1-8) is a tetrahedral around the mercury (II) ion. http://dx.doi.org/10.25130/tjps.24.2019.086

Qualitative Analysis of Test Strip for Sildenafil Citrate with Some Combinations Reagen in Cellulosa Paper Membran

Sildenafi l citrate was widely used to treat erectile dysfunction in men. The high demand of this drug, infl uence of counterfeit drugs. Therefore, it is required an analytical method to determine the authenticity of this drug. The aims of this research were to develop and evaluate of strip test for sildenafi l sitrat identifi cation. Research was conducted by preparation of solution and choosing the appropriate reagent for sildenafi l citrate. The optimum reagents were immobilized in cellulose paper followed by manufactured into strip test. Product performance was evaluated by evaluating several test in termed of qualitative, reproducibility, specifi city and response time. The results showed that the optimum membrane product was consisted of copper sulfate and sodium bicarbonate (2:1); ammonium ferric sulfate hexahydrate and copper acetat (1:3); sodium sulfate, copper acetate and ammonium ferrite sulfate (2:1:1) and mercury acetate and copper sulfate (2:1) reagents. The strip test had a capability in specifi c identify of sildenafi l citrate with a good reproducibility and less than ten seconds for time response. The strip test developed could be used as an early detection tool for the authenticity of a sildenafi l citrate tablet which more rapid.

Direct C-metallation of N-substituted triazoles promoted by mercury acetate. An alternative route to N-heterocyclic carbene complexes

One-pot synthesis of C-bound triazolate complexes of mercury(ii) from N-substituted triazoles with Hg(OAc)2 have been achieved. Further methylation of one of these complexes yielded a monomeric N-heterocyclic carbene complex.

Synthesis and Characterization of Mercury(II) Complexes Containing 2,9-Dimethyl-1,10-phenanthroline by Sonochemical Method

Synthesis and characterization of microstructured crystalline complexes of [HgI2(C14H12N2)] and [HgBr2(C14H12N2)] were carried out from the reaction between 2,9-dimethyl-1,10-phenanthroline, mercury acetate, KI, and KBr, respectively, in methanol by sonochemical method. The reaction conditions were optimized under ultrasonic irradiations and without it. Characterization of the complexes was performed by elemental analysis, XRD, SEM, FTIR, and thermal analysis (TG/DTA). The results showed that sonochemical method caused significant reduction of the reaction time. Then the products were put under supercritical condition in a Teflon-lined, stainless-steel Parr bomb container and heated at 150°C for 48 h. The results showed that the chemical formulas of the complexes were not changed; however, the particle sizes were reduced and porosity increased.