In vivo removal of radioactive cesium compound using Prussian blue-deposited iron oxide nanoparticles

Aim: To mitigate the side effects of medical treatment by Prussian blue (PB), a well-known adsorbent for radioactive cesium (Cs), PB-deposited magnetic nanoparticles (MNPs), were prepared and analyzed on the adsorbent capacity for Cs removal. Materials & methods: The PB-deposited MNPs were prepared by photo-deposition method and investigated for their Cs adsorption properties in vitro and in vivo. The distribution of the adsorbents was also evaluated in C57BL/6 mice. Results: PB-deposited MNPs provided an improved adsorbent capacity for Cs removal and reduced toxicity to blood cells compared with those of bulk PB. Conclusion: PB-deposited MNPs could be considered as an alternative of PB-based medicine to reduce the possible hazards caused by high dose of PB intake.

Validation of Modified ART Mod 2 Code through Comparison with Aerosol Deposition of Cesium Compound in Phébus FPT3 Containment Vessel

Evaluation of aerosol deposition in the containment vessel is an important step for the assessment of radioactive material release to the environment. ART Mod 2 is a calculation code that is used for evaluation of aerosol deposition in the containment vessel. The authors modified aerosol deposition models of ART Mod 2, namely, gravitational settling model, Brownian diffusion model, diffusiophoresis model, and thermophoresis model in order to increase potential of capturing the deposition phenomena. This study aims to compare the simulated results of modified ART Mod 2 with aerosol deposition of cesium compounds in the containment vessel of Phébus FPT3 experiment, in order to validate modified ART Mod 2 code. It is found that aerosol deposition using modified ART Mod 2 agrees with Phébus FPT3. Prediction of Brownian diffusion is significantly improved due to the consideration of turbulent damping process. Cesium mass flow rate and aerosol size are factors that can significantly influence the uncertainty of the results. When conditions of single volumes are carefully selected to match those of the Phébus FPT3 experiment, modified ART Mod 2 can predict aerosol deposition in Phébus FPT3 with relative accuracy.