Juvenile psammomatoid ossifying fibroma of maxilla: A case report

Juvenile psammomatoid ossifying fibroma is histological variant of juvenile ossifying fibroma, a fibro-osseous tumor of craniofacial bones with benign but potentially aggressive nature. Complete excision of tumor is essential as it is associated with very high recurrence rate. We have reported here a case of juvenile ossifying fibroma- a psammomatoid variety present in right maxilla in a 13-year old male child. Complete excision of tumor was done through intra-oral approach with the 2.5 years of follow up shows no recurrence.Juvenile psammomatoid ossifying fibroma is fibro-osseous tumor of craniofacial bones with benign but potentially aggressive nature. Complete excision of tumor is essential as it is associated with very high recurrence rate.

Juvenile psammomatoid ossifying fibroma of the parietal bone and review of calvarial presentations: illustrative case

BACKGROUND Juvenile psammomatoid ossifying fibroma (JPOF) is an uncommon benign fibro-osseous lesion that only rarely presents in the calvaria. OBSERVATIONS The authors reported a case of JPOF in the left parietal bone of a 20-year-old patient and reviewed the 27 other cases of JPOF occurring in the calvaria as reported in the literature. LESSONS JPOF rarely presents in the calvaria, and because diagnosis is a histopathologic one, clinicians should consider this entity when presented with a lytic, expansile mass on imaging. Little is known about the molecular mechanisms driving development of JPOF. MDM2 amplification may play a role, although this was not seen in the case presented herein.

Transcranial resection of a juvenile psammomatoid ossifying fibroma of the orbit: A case report with 2-year follow-up

Background: Juvenile psammomatoid ossifying fibromas (JPOFs) are benign, locally invasive lesion of the craniofacial skeleton that may undergo rapid growth resulting in damage to cranial and facial structures. They usually occur before the age of 15 years and should be carefully treated as their diagnosis may be confused with other lesions such as psammomatous meningioma. Case Description: A 14-year-old male presented to the clinic with a history of progressive left proptosis. Imaging studies revealed a well-circumscribed lesion involving the left orbital roof and showing internal areas of calcification and sclerosis. He underwent a transcranial resection of the lesion and follow-up imaging revealed no evidence of recurrence. Conclusion: JPOFs are locally invasive lesions that require careful diagnosis and meticulous excision to prevent recurrence.

Tratamento cirúrgico de fibroma ossificante juvenil psamomatoide: relato de caso clínico

Introdução: O fibroma ossificante juvenil psamomatoide é um neoplasma de tecido conjuntivo fibroso celularizado, tipicamente não encapsulados de limites bem definidos, de crescimento rápido e assintomático, acometendo principalmente maxila de pacientes jovens. O diagnóstico geralmente acontece pela observação clínica da expansão cortical e deformidade facial evidente. Radiograficamente apresentam-se como lesões radiolúcidas circunscritas, com possíveis áreas radiopacas centrais. O tratamento cirúrgico através da excisão cirúrgica e curetagem parece ser o mais adequado em vista da agressividade expansiva da lesão e da baixa taxa de recidiva. Objetivo: O objetivo desse trabalho é relatar o tratamento cirúrgico de um paciente do gênero masculino, jovem, diagnosticado com fibroma ossificante juvenil psamomatoide de grande dimensões em seio maxilar esquerdo. Caso clínico: Clinicamente assintomático, com expansão da cortical óssea em fundo de sulco maxilar esquerdo, divergência de raízes dentárias, estreitamento da fossa nasal e deformidade facial esquerda, o exame radiográfico panorâmico evidenciava lesão radiolúcida circunscrita com áreas radiopacas. O tratamento de escolha foi a excisão cirúrgica completa da lesão através do acesso único de Weber-Ferguson para prover adequado acesso a todas as regiões envolvidas e manutenção da morfologia da face por meio de reconstrução com malha de titânio. Este relato de caso ilustra a conduta frente a fibroma ossificante juvenil psamomatoíde de grande proporção. Conclusão: Apesar do acesso cirúrgico eleito, a estética facial foi pouco comprometida, a malha de titânio proveu manutenção apreciável do tecido mole e a área operada encontra-se em acompanhamento pós-operatório para eventual futura reconstrução.Descritores: Fibroma Ossificante; Neoplasias de tecido ósseo; Cirurgia; Weber-Ferguson; Lesões fibro-ósseas.ReferênciasFigueiredo LM, de Oliveira TF, Paraguassú GM, de Hollanda Valente RO, da Costa WR, Sarmento VA. Psammomatoid juvenile ossifying fibroma: case study and a review. Oral Maxillofac Surg. 2014;18(1):87-93.Speight PM, Takata T. New tumour entities in the 4th edition of the World Health Organization Classification of Head and Neck tumours: odontogenic and maxillofacial bone tumours. Virchows Arch. 2018;472(3):331-39.Linhares P, Pires E, Carvalho B, Vaz R. Juvenile psammomatoid ossifying fibroma of the orbit and paranasal sinuses. A case report. Acta Neurochir (Wien). 2011;153(10):1983-88.Figueiredo LMG, Valente ROH, Sarmento VA, Trindade SC, Oliveira TFL, Costa WRM. Aspectos atuais no diagnóstico e tratamento do fibroma ossificante juvenil. Rev bras cir cabeça pescoço. 2012;41(2):99-102.Agarwal SP, Kumar S, Singh HP, Usmani SA. Huge ossifying fibroma maxilla. Natl J Maxillofac Surg. 2015;6(2):241-43.Neville BW, Damm DD, Allen CM, Bouquot JE. Patologia oral e maxilofacial. 3.ed. Rio de Janeiro: Elsevier; 2009.El-Mofty S. Psammomatoid and trabecular juvenile ossifying fibroma of the craniofacial skeleton: two distinct clinicopathologic entities. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;93(3):296-304.Nogueira RLM, Nonaka CFW, Cavalcante RB, Carvalho AC, Souza LB. Fibroma ossificante juvenil localizado em mandíbula: relato de caso e breve revisão da literatura. Rev cir traumatol buco-maxilo-fac. 2009; 9(1):25-32.Ranganath K, Kamath SM, Munoyath SK, Nandini HV. Juvenile psammomatoid ossifying fibroma of maxillary sinus: case report with review of literature. J Maxillofac Oral Surg. 2014;13(2):109-14.Toro C, Millesi W, Zerman N, Robiony M, Politi M. A case of aggressive ossifying fibroma with massive involvement in the mandible: differential diagnosis and management options. Int J Pediatr Otorhinolaryngol. 2006 Extra 1:167-72.Leimola-Virtanen R, Vähätalo K, Syrjänen S. Juvenile active ossifying fibroma of the mandible: a report of 2 cases. J Oral Maxillofac Surg. 2001;59(4):439-44.Papadaki ME, Troulis MJ, Kaban LB. Advances in diagnosis and management of fibro-osseous lesions. Oral Maxillofac Surg Clin North Am. 2005;17(4):415-34.Santos JN, Vieira TSLS, Góis Filho DM, Vasconcelos SJA, Azevedo RA. Displasia fibrosa: osteoplastia com acesso Weber-Ferguson. Relato de caso. Rev cir traumatol buco-maxilo-fac. 2010;10(1):73-80.Melo RB, Silva PF, Gonçalves FLN, Rodrigues AL, Pontes HAR. Tratamento cirúrgico de granuloma central de células gigantes agressivo em maxila com acesso Weber Ferguson: Relato de caso. Rev cir traumatol buco-maxilo-fac. 2014; 14(4):65-70.Reddy AV, Reddy KR, Prakash AR, Rajinikanth, Vidhyadhari P. Juvenile ossifying fibroma with aneurysamal bone cyst: a case report. J Clin Diagn Res. 2014;8(10):ZD01-ZD2.Slootweg PJ, Müller H. Juvenile ossifying fibroma. Report of four cases. J Craniomaxillofac Surg. 1990;18(3):125-29.Chiavaioli GMO. Fibroma ossificante juvenil em mandíbula: Relato de caso [monografia]. Belo Horizonte: Faculdade de Odontologia da Universidade Federal de Minas Gerais; 2015.

Juvenile psammomatoid ossifying fibroma of the calcaneus

Juvenile ossifying fibromas (JOFs) are a rare group of fibro-osseous lesions, typically of odontogenic origin. Juvenile psammomatoid ossifying fibroma (JPOF) is one variant, that is, histopathologically distinguished by spherical ossicles resembling psammoma bodies. JPOF tumours are most commonly found in craniofacial skeletal structures and can be locally aggressive. Thus, early management by complete surgical excision is crucial for good outcomes, although recurrence is still possible. Secondary aneurysmal bone cyst (ABC) formation has been reported with JOF lesions, but less commonly with the JPOF variant. We describe an unusual case of JPOF that presented in the calcaneus with secondary ABC formation.