Awareness and Behavior to Prevent Coronavirus Pandemic: A Case Study of Young People in Southern Of Vietnam

The study was conducted to explore public awareness and behaviors in response to the COVID-19 pandemic through a survey of 302 young people in the southern provinces of Vietnam. The Confirmatory Factor Analysis (CFA) and Structural Equation Modeling (SEM) were applied to validate relationships between elements of the modeling. The research shown that knowledge of pandemic, awareness of the benefits of preventive measures, and trust in the Government’s effort in disease prevention had a positive impact on preventive behavior against COVID-19. It takes proportional effect on proactive behavior in purchasing daily goods and medical products.

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Background: REGEN-COV is a combination of 2 monoclonal antibodies (casirivimab and imdevimab) that bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike protein. We aimed to evaluate the efficacy and safety of REGEN-COV in patients admitted to hospital with COVID-19. Methods: In this randomised, controlled, open-label platform trial, several possible treatments were compared with usual care in patients hospitalised with COVID-19. Eligible and consenting patients were randomly allocated (1:1) to either usual standard of care alone (usual care group) or usual care plus a single dose of REGEN-COV 8g (casirivimab 4g and imdevimab 4g) by intravenous infusion (REGEN-COV group). The primary outcome was 28-day mortality assessed first among patients without detectable antibodies to SARS-CoV-2 at randomisation (seronegative) and then in the overall population. Findings: Between 18 September 2020 and 22 May 2021, 9785 patients were randomly allocated to receive usual care plus REGEN-COV or usual care alone, including 3153 (32%) seronegative patients, 5272 (54%) seropositive patients and 1360 (14%) patients with unknown baseline antibody status. In the primary efficacy population of seronegative patients, 396 (24%) of 1633 patients allocated to REGEN-COV and 451 (30%) of 1520 patients allocated to usual care died within 28 days (rate ratio 0.80; 95% CI 0.70-0.91; p=0.0010). In an analysis involving all randomised patients (regardless of baseline antibody status), 944 (20%) of 4839 patients allocated to REGEN-COV and 1026 (21%) of 4946 patients allocated to usual care died within 28 days (rate ratio 0.94; 95% CI 0.86-1.03; p=0.17). The proportional effect of REGEN-COV on mortality differed significantly between seropositive and seronegative patients (p value for heterogeneity = 0.001). Interpretation: In patients hospitalised with COVID-19, the monoclonal antibody combination of casirivimab and imdevimab (REGEN-COV) reduced 28-day mortality among patients who were seronegative at baseline.

Customer Satisfaction of Vietnam Airline Domestic Services

The paper examines relation between Vietnam Airline Domestic service quality and consumer satisfaction by gathering opinions from 402 passengers employing Skytrax scale with some modification along with Cronbach’s alpha, EFA and multiple regression analysis. Results show that Vietnam Airline Domestic service quality can be measured by the following six determinants in order of decreasing importance: (1) boarding/deplaning/baggage; (2) check in; (3) in-flight services; (4) reservation; (5) aircraft; and (6) flight crew. All of them are directly proportional effect to customer satisfaction. The paper also offers some suggestions to improve the service quality thereby enhancing the customer satisfaction.

The lengths of spinal curvature stretch due to the angles of sitting on saddle chair to alleviate back pain: A statistical analysis

BACKGROUND: By dividing the burden of one’s weight between the shins and the buttocks in the sitting position on an office or saddle chair, a person can avoid back pain. In this 21st century, sitting on a chair for long hours in workplace on office chair is unavoidable necessity and hence, millions in different countries undergo a risk for backpain. Is there a right sitting position? OBJECTIVE: The aim of this article is to find out how much a correlation exists between the angle of sitting and the length of spinal curvature which is the source of backpain. An experiment can be designed and carried out to measure various angles in sitting and the changing length of the person’s length of spinal cord curvature. METHOD: The usual statistical methodology requires a pair of values namely x and y to quantify the correlation. The data on sitting angles and the length of spinal curvature do not have such pairing, and hence, the traditional approach to find the correlation between the sitting angle and length of spinal curvature is not applicable. Yet, an approach is necessary. This article constructs an innovative statistical approach to fulfil this need. RESULTS: Our approach yields a correlation of 0.998 for sitting on office chair and an increased correlation of 0.999 on saddle chair, according to the Truszczy'nska-Baszaka et al.’s data. CONCLUSIONS: An adjustment is made in various angles of sitting on office chair to transform the comfortable sitting on a saddle chair. In consequence, the proportional effect on the spinal curvature is estimable with the data and it is phenomenal (that is significantly more than one). No wonder people prefer saddle chair over office chair when it comes to avoid back pain and this article proves the convenience statistically.

Correlation of Blood Oxidative Stress Parameters to Indoor Radiofrequency Radiation: A Cross Sectional Study in Jordan

Background: Electromagnetic pollution is a general health concern worldwide, as cell phone towers are ubiquitous and are located adjacent to or on the roof of schools, and hospitals. However, the health risks are still inconclusive. This cross-sectional study evaluated the potential effect of electromagnetic radiation generated from various resources including cell phone towers on blood glutathione S transferase activity (e-GST) and total antioxidant activity of the Jordanian population. Methods: The power density of three districts in the city of Irbid, Jordan was mapped to generate “outside the houses” and “inside the houses” maps. The effect of categorical variables (gender, using a cell phone, presence of Wi-Fi modem, previous exposure to medical imaging) and continuous variables (distance from the base station, the elevation of the house, the duration of stay in the house, power density outside houses, power density inside houses) on e-GST and total antioxidant activity were investigated. Results: The EMR generated outside the houses—including cell phone towers—did not reach inside the houses at the same power and had no significant influence on e-GST activity. The EMR inside the house, which primarily came from internal resources, has a significant effect on e-GST activity. The duration of stay inside the house, the use of cell phones, and the presence of a Wi-Fi modem had a proportional effect on e-GST activity. The total antioxidant activity was statistically equal between the tested and control groups. Conclusions: Several factors such as building materials restricted the penetration of EMR reaching inside the houses. EMR generated inside rather than outside the houses had a proportional effect on e-GST. The differences in e-GST were compensated successfully by other antioxidant mechanisms. Further research is needed to identify other possible sources of antioxidants, and to evaluate long-term effects and genetic polymorphism.

Aviation

The paper examines relation between Vietnam Airline Domestic service quality and customer satisfaction by gathering opinions from 402 passengers employing Skytrax scale with some modification along with Cronbach’s alpha, EFA and multiple regression analysis. Results show that Vietnam Airline Domestic service quality can be measured by the following six determinants in order of decreasing importance: (1) boarding/deplaning/baggage; (2) check in; (3) in-flight services; (4) reservation; (5) aircraft; and (6) flight crew. All of them are directly proportional effect to customer satisfaction. The paper also offers some suggestions to improve the service quality thereby enhancing the customer satisfaction.

Effect of Polyethylene Strips Surface Roughness on Its Efficiency for Enhancement of Wastewater Treatment

This study aimed to determine the effect of roughness surface for polyethylene strips on its quality for enhancement the characteristics of wastewater treatment plant effluent as a very cheap method. The study was applied at Abu Rawash WWTP effluent channel using the smooth and rough polyethylene strips where a biofilm layer forms above its surface. The removal ratio for smooth polyethylene strips for BOD and TSS was 4.45 and 4.33% respectively, while for the rough polyethylene strips was 14.10 and 13.37 respectively. This shows the success of the polyethylene strips even smooth or rough to remove both the BOD and TSS from treated wastewater. The results show that the material roughness affected the treatment efficiency with proportional effect. And the rough surface has a good removal efficiency that makes it more applicable for such purpose of enhancing the treated wastewater with very low cost technique.

Can't wait to get my pension: the effect of raising the female early retirement age on income, poverty and deprivation

We estimate the impact of increasing the female early retirement age (ERA) on household living standards. Examining the increase in the female ERA from 60 to 63 in the UK, we find increased earnings only partially offset lost public pension income, leaving affected women's household incomes £32 per week lower on average. The proportional effect was substantially larger for women in lower income households. This increased the income poverty rate among affected women by 6.4 percentage points. We find no evidence of an increased inability to afford important material items, potentially suggesting that material deprivation has been avoided through smoothing of consumption.

Use of an individual-based model of pneumococcal carriage for planning a randomized trial of a vaccine

For encapsulated bacteria such asStreptococcus pneumoniae, asymptomatic carriage is more common and longer in duration than disease, and hence is often a more convenient endpoint for clinical trials of vaccines against these bacteria. However, using a carriage endpoint entails specific challenges. Carriage is almost always measured as prevalence, whereas the vaccine may act by reducing incidence or duration. Thus, to determine sample size requirements, its impact on prevalence must first be estimated. The relationship between incidence and prevalence (or duration and prevalence) is convex, saturating at 100% prevalence. For this reason, the proportional effect of a vaccine on prevalence is typically less than its proportional effect on incidence or duration. This relationship is further complicated in the presence of multiple pathogen strains. In addition, host immunity to carriage accumulates rapidly with frequent exposures in early years of life, creating potentially complex interactions with the vaccine’s effect. We conducted a simulation study to predict the impact of an inactivated whole cell pneumococcal vaccine—believed to reduce carriage duration—on carriage prevalence in different age groups and trial settings. We used an individual-based model of pneumococcal carriage that incorporates relevant immunological processes, both vaccine-induced and naturally acquired. Our simulations showed that for a wide range of vaccine efficacies, sampling time and age at vaccination are important determinants of sample size. There is a window of favorable sampling times during which the required sample size is relatively low, and this window is prolonged with a younger age at vaccination, and in a trial setting with lower transmission intensity. These results illustrate the ability of simulation studies to inform the planning of vaccine trials with carriage endpoints, and the methods we present here can be applied to trials evaluating other pneumococcal vaccine candidates or comparing alternative dosing schedules for the existing conjugate vaccines.Author SummaryStreptococcus pneumoniae, a bacterium carried in the nasopharynx of many healthy people, is also a leading cause of bacterial pneumonia, sepsis, and ear infections in children aged five years and younger. Vaccines targeting select strains ofS. pneumoniaehave been effective, and the development of new vaccines, particularly those that target all strains, can further lower disease burden. For clinical trials of these vaccines, the number of study participants needed depends on the expected effect of the vaccine on a conveniently measured outcome: asymptomatic carriage. The most economical way to test a vaccine for its effect on carriage is by measuring prevalence at a specific time, and comparing vaccinated to unvaccinated participants. The relationship between incidence (or duration) and prevalence is complex, and changes with time as children develop natural immunity. We explored this relationship using a mathematical model. Given a vaccine efficacy, our computer simulations predict that fewer study participants are needed if they are vaccinated at a younger age, taken from a population with intermediate levels of transmission, and sampled for carriage at a certain time window: 9 to 18 months after vaccination. Our study illustrates how simulation studies can help plan more efficient vaccine trials.