Face transplantation

Facial composite tissue allotransplantation is an emerging field which offers the potentially restore facial form and function, even following the most severe traumatic injuries. This benefit must be carefully weighed against the need to lifelong immunosuppression, associated infection risks, and possible rejection. Patients must be carefully screened for medical and psychiatric issues prior to the procedure. However, in the well-selected patient, this procedure can be transformative. Uniformly, patients self-report a dramatic improvement post transplantation. In addition, return of sensation in the transplanted allograft occurs in 3–6 months, although return of motor function takes longer and remains incomplete. Ultimately, facial composite tissue transplantation is a powerful technique in the properly selected patient.

Facial Transplantation

Although significant advances in craniofacial and microsurgical reconstructive techniques have allowed for the reliable reconstruction of complex head and neck defects, there are limitations to conventional therapy. In the past decade, the medical community has witnessed the growth and evolution of facial transplantation in becoming a clinical reality for the most severely disfigured individuals. Despite recent advances and promising short-term results, the risk-benefit trade-off is still evolving as more experience is gained. This chapter provides a comprehensive overview of indications, recipient evaluation, and immunosuppression. The latest outcomes’ data including functional outcomes, costs, quality of life, complications, and deaths from the emerging field of facial transplantation are also reviewed. This review contains 11 figures, 5 tables and 92 references Key Words: Facial Transplantation, Vascularized composite allotransplantation, Composite tissue transplantation, Reconstruction Microsurgery, Craniofacial Surgery, Transplant Surgery, Immunosuppression, Functional Outcomes

Uterus Transplantation: An Update and Preparations for Introduction in India

ABSTRACT The clinical field of composite tissue transplantation now also includes uterus transplantation (UTx), a new type of quality-oflife enhancing and in this case also life-giving transplantation. The purpose of UTx is to enable live birth from a woman who lacks uterus or in a woman who has a defective uterus. How to cite this article Rao KA, Dahm-Kähler P, Brännström M. Uterus Transplantation: An Update and Preparations for Introduction in India. Int J Infertil Fetal Med 2016;7(2):61-67.