xenon clearance
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1990 ◽  
Vol 5 (3) ◽  
pp. 165-172 ◽  
Author(s):  
T. R. Cheatle ◽  
G. M. McMullin ◽  
J. Farrah ◽  
P. D. Coleridge Smith ◽  
J. H. Scurr

No investigation exists which has been shown to detect accurately microcirculatory improvement following treatment for chronic venous insufficiency. This study examines three possible techniques for doing so. Fourteen patients with chronic venous insufficiency and fourteen controls underwent measurement of transcutaneous PO2, 133xenon clearance from the skin and subcutaneous tissues and laser–Doppler flowmetry in the gaiter region. Patients with venous disease then followed a regime of intermittent pneumatic compression for 4 h each day for 4 weeks. The same measurements were then repeated. Xenon clearance from subcutaneous fat and the time taken to reach maximal laser–Doppler flow after release of a tourniquet showed a significant improvement after compression treatment. These tests may be useful as parameters in the objective monitoring of response to treatment in patients with liposclerotic skin.


1990 ◽  
Vol 73 (3A) ◽  
pp. NA-NA
Author(s):  
T J Quill ◽  
D R Spahn ◽  
J Lu ◽  
F H Kern ◽  
W J Greeley ◽  
...  
Keyword(s):  

1990 ◽  
Vol 99 (2) ◽  
pp. 155-159 ◽  
Author(s):  
Robert M. Naclerio ◽  
Denise Bartenfelder ◽  
Cynthia Fisher ◽  
Daniel Koller ◽  
Cahid A. Civelek ◽  
...  
Keyword(s):  
Dry Air ◽  

1984 ◽  
Vol 18 ◽  
pp. 375A-375A
Author(s):  
Patricia H Ellison ◽  
John L Horn ◽  
Gorm Greisen ◽  
Keld Johansen ◽  
Polly Brown

1984 ◽  
Vol 56 (1) ◽  
pp. 24-30 ◽  
Author(s):  
P. Cerretelli ◽  
C. Marconi ◽  
D. Pendergast ◽  
M. Meyer ◽  
N. Heisler ◽  
...  

The accuracy of muscle blood flow measurement by the 133Xe clearance method (QXe) was assessed against direct venous outflow (Qv) and microsphere trapping flow (Q mu) determinations in isolated perfused dog gastrocnemius both at rest and during graded stimulation [O2 consumption (VO2) up to 12 ml X 100 g-1 X min-1] and in the gastrocnemius, vastus lateralis, and triceps of intact dogs at rest and while running on a treadmill at varied speeds up to maximum VO2. In 29 measurements performed in 11 isolated muscles, Q mu was in good agreement with Qv at rest and at all stimulation levels (Q mu/Qv = 1.0; r = 0.98). 133Xe clearance yielded much lower blood flows than the venous outflow and the microsphere trapping methods. In 43 measurements in 11 muscles, the mean QXe/Qv ratio was 0.57 +/- 0.03 (SE), independent of blood flow. Similarly, in 65 measurements in 2 intact dogs, the mean QXe/Q mu ratio in all tested muscles was 0.49 +/- 0.02 (SE), independent of blood flow. These results show that the 133Xe clearance method considerably underestimates blood flow in dog muscles.


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