3D photography versus digital planimetry in wound measurement : a systematic review protocol

Review question / Objective: The aim of this study is to find whether there is concordance between two methods of wound area measurement: 3D photography and digital planimetry. Condition being studied: One of the most important factors in all types of wound management is wound measurement and two new digital techniques are : digital planimetry and 3D-photography. Eligibility criteria: the articles will be included only if the study cases would be measured by both methods of wound measurement including 3D photography and digital planimetry. patients with wound in any area of their body like diabetic ulcers, venous ulcers or burning. not models or animals.not bite or scar or bruising. without any restriction in age or gender.

[REiNS] Validating Techniques for Measurement of Cutaneous Neurofibromas: Recommendations for Clinical Trials

Objective:To assess the reliability and variability of digital calipers, 3D photography, and high frequency ultrasound (HFUS) for measurement of cutaneous neurofibromas (cNF) in patients with neurofibromatosis type 1 (NF1).Background:cNF affect virtually all patients with NF1 and are a major source of morbidity. Reliable techniques for measuring cNF are needed to develop therapies for these tumors.Methods:Adults with NF1 were recruited. For each participant, six cNF were assessed independently by three different examiners at five different timepoints using digital calipers, 3D photography, and HFUS. The intraclass correlation coefficient (ICC) was used to assess intra- and inter-rater reliability of linear and volumetric measurements for each technique, with ICC values >0.90 defined as “excellent” reliability. The coefficient of variation (CV) was used to estimate the minimal detectable difference (MDD) for each technique.Results:57 cNF across 10 participants were evaluated. The ICC for image acquisition and measurement was >0.97 within and across examiners for HFUS and 3D photography. ICC for digital calipers was 0.62–0.88. CV varied by measurement tool, linear vs. volumetric measurement, and tumor size.Conclusions:HFUS and 3D photography demonstrate “excellent” reliability whereas digital calipers have “good” to “excellent” reliability in measuring cNF. The MDD for each technique was used to create tables of proposed thresholds for investigators to use as guides for clinical trials focused on cNF size. These criteria should be updated as the performance of these endpoints are evaluated.

Disturbance-Region Removal on Landmark-less Registration of Craniofacial Images Acquired by CBCT and 3D Photography

Superimposition of cranio-maxillofacial images acquired from cone-beam computed tomography (CBCT) and facial images acquired from three-dimensional photography (3D photography) can assist in diagnosis and surgical planning. Conventional approaches individually identified prominent facial landmarks on both modalities, respectively and assessed their correspondence. Considering, however, variation of facial expressions or drastic feature distortion when the face or head was imaged at different timing, landmark registration can become challenging. This paper proposes a disturbance-region removal (DRR) procedure to improve the efficacy of registration. The disturbance regions (DRs) are defined as those exhibiting strong responses in the concavity intensity maps that are computed from the facial surface mesh. Following this identification process for the DRs, an adapted symmetric region growing algorithm is used to form the connected DRs that are to be removed prior to superimposition of both modalities. The results show a twenty-eight percent better match of overall correspondence of the facial fiducial markers. Instead of being the registration guides in conventional approaches, in this study the fiducial markers are employed as only a means to assess the performance of registration