REAL CLINICAL PRACTICE OF POSTPARTUM ANAL INCONTINENCE TREATMENT IN RUSSI

Aim: To evaluate the medical care quality provided to patients with fecal incontinence in practice; to investigate the patient care effectiveness; to identify the problems the patient and the doctor are faced during the postpartum anal incontinence (AI) treatment.Methods: A questionnaire for surgeons was created using Google forms. It includes 22 questions about medical characteristics of patients with AI, used diagnostic methods, and treatment results. The answers were analyzed and presented as histograms.Results: Totally 134 (17.4%) questionnaires were completed from September to November 2020. Labor was the most common AI cause (74.4%). The median age was 20-40 years, 37% of patients was >40 years, 8% – >60 years. The most common complaints were incontinence (70%) and decreased life quality (72%). Rectovaginal fistulas were diagnosed in 28% of cases. The sphincter complex lesion size, age and anorectal manometry results determined the treatment strategy. Only 8.8% of surgeons suggested sacral neurostimulation in case of the other methods inefficiency. Up to 16.7% of patients were offered to create stoma as the final treatment method.Discussion: Our study is the first major survey for proctologists and surgeons in Russia, assessing the medical care of patients with postpartum AI. The results indicate insufficient attention to this problem; it requires educational and organizational solutions. Regional or federal centers where obstetrician and surgeons can work cooperatively could be extremely helpful to provide appropriate medical care to these patients and to improve the treatment quality for women with postpartum AI.

Timing of sacral neurostimulation is important for increasing bladder capacity in the anesthetized rat

We assessed the effects of limited application of sacral neurostimulation (SNS) during bladder filling on bladder capacity using our previously published SNS model in rats. Female Sprague-Dawley rats ( n = 24) were urethane anesthetized (1.2 g/kg sc) and implanted with jugular venous and transvesical bladder catheters. L6/S1 nerve trunks were isolated bilaterally, and two electrodes were placed on each exposed nerve. True bladder capacity (TBC) was determined using stable single-fill cystometrograms. In the first series of experiments, SNS was applied at the onset of bladder filling for 25%, 50%, 75%, and 100% of the previous control filling cycle duration ( n = 10). In the second series of experiments, SNS was applied during the first, second, third, and fourth 25% and the first and second 50% of the control fill. In the first series, a significant increase in TBC was observed only when SNS was applied for 75% or 100% of the control fill duration (30% and 35%, respectively, P < 0.05). In the second series, significant increases in TBC only occurred during the fourth 25% period and second 50% period (32% and 43%, respectively, P < 0.001). Results from the second series also revealed an increase in subsequent single-fill bladder capacities (TBC) only when SNS was applied during the second 50% of the prior fill cycle. These data indicate that the application of SNS during the final 50% of the bladder fill cycle is necessary and sufficient for increasing bladder capacity.