COVID-19: Morphology, Characteristics, Symptoms, Prevention, Clinical Diagnosis and Current Scenario

Background: There are different types of viruses found in nature which cause infection in humans and other animals, some causing severe illness and others not. A unique coronavirus termed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was isolated from lower respiratory tract sample as the causative agent. Objective: This review article includes characteristics of COVID-19, current scenario of disease, causes and symptoms of disease and how to prevent from its infection. Methods: We accomplished a comprehensive evaluation of the communication amid COVID-19 disease and serious effects of the disease. There are many articles describing the general characteristics, prevention and its harmful effects on humans which were included. The clinical diagnosis and present scenario of the disease were also reviewed. Results: The recent outbreak of contagions with SARS-CoV-2 is termed Coronavirus Disease 2019 (COVID-19) by the World Health Organization (WHO). Many governments of the world, scholars and scientists are engaged to discover the proper treatment and until a proper and right treatment for it is found, we have to be careful to avoid infection. Conclusion: At present, the whole world is struggling with COVID-19 disease. COVID-19 quickly spread into at least 215 countries and exterminated more than 300,000 persons by May 15, 2020. This is the time to exercise restraint and caution. The rapid extent of disease allows deep examination and quarantine conventions to prevent further transmission.

Recurrence of SARS-CoV-2 RNA in upper respiratory tract samples from recovered patient with coronavirus disease 2019 (COVID-19)

BackgroundCase isolation and contacts tracing are the most widely used strategies to control the outbreak of COVID-19. However, little attention has been paid to the infectiousness of recovered patients with COVID-19.Case presentationIn this study, we reported a confirmed case of COVID-19 whose nasopharyngeal swab test of SARS-CoV-2 RNA turned positive 28 days after hospital discharged.ConclusionsSARS-CoV-2 RNA can be detected in respiratory tract sample 28 days after hospital discharged. Further studies about consecutive detection of SARS-CoV-2 combined with viral isolation among COVID-19 cases should be designed to determine the accurate contagious period.

Epidemiology, virology, and clinical features of severe acute respiratory syndrome -coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19)

A cluster of severe pneumonia of unknown etiology in Wuhan City, Hubei province in China emerged in December 2019. A novel coronavirus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was isolated from lower respiratory tract sample as the causative agent. The current outbreak of infections with SARS-CoV-2 is termed Coronavirus Disease 2019 (COVID-19) by the World Health Organization (WHO). COVID-19 rapidly spread into at least 114 countries and killed more than 4,000 people by March 11 2020. WHO officially declared COVID-19 a pandemic on March 11, 2020. There have been 2 novel coronavirus outbreaks in the past 2 decades. The outbreak of severe acute respiratory syndrome (SARS) in 2002–2003 caused by SARS-CoV had a case fatality rate of around 10% (8,098 confirmed cases and 774 deaths), while Middle East respiratory syndrome (MERS) caused by MERSCoV killed 861 people out of a total 2,502 confirmed cases between 2012 and 2019. The purpose of this review is to summarize known-to-date information about SARS-CoV-2, transmission of SARS-CoV-2, and clinical features.