BIOSATELLITES BION 6-11: INVESTIGATIONS WITH PRIMATES

In 1951, the USSR started launching rockets with dogs in preparation of the first human space flight. The US, starting in 1948, launched primates. These launches of rockets with animals pursued primarily the objectives of engineering testing, whereas the actual researches with primates in orbital flights in US and USSR began in 1969 and 1983, respectively. USSR/Russia launched 12 rhesus-macaques onboard 6 biosatellites of the BION series. The main goal of the investigations was to attack the so-called space adaptation syndrome. Implanted and applied electrodes provided unique information about progression of the space motion sickness, motor dysfunction and growth of intracranial pressure in the condition of microgravity. The BION program was conducted in a broad cooperation with international partners.

Passive force control of multimodal astronaut training robot

For the purpose of solving the problem of astronaut training in weightlessness environment, this article proposes a multimodal astronaut training robot to enable astronauts to perform running, bench press and deep squat training in the weightless environment, so as to help them mitigate the adverse effects brought by the space adaptation syndrome. Taking the modularized wire driving unit as the research object, the dynamic model of the passive force servo system was established; and the passive force control strategy was designed. The experimental results show that the system is of good stability, high steady-state accuracy, and excellent dynamic quality after correction. When the given signal frequency is 10 Hz, the system phase lag is about 9°, and the loading error is about 5%. The passive force servo control strategy can effectively reduce the surplus force. When the speed disturbance frequency of carrying unit is within 3 Hz, the elimination rate of the surplus force can reach 90%.

Noninvasive in-ear monitoring of intracranial pressure during microgravity in parabolic flights

Among possible causes of visual impairment or headache experienced by astronauts in microgravity or postflight and that hamper their performance, elevated intracranial pressure (ICP) has been invoked but never measured for lack of noninvasive methods. The goal of this work was to test two noninvasive methods of ICP monitoring using in-ear detectors of ICP-dependent auditory responses, acoustic and electric, in acute microgravity afforded by parabolic flights. The devices detecting these responses were handheld tablets routinely used in otolaryngology for hearing diagnosis, which were customized for ICP extraction and serviceable by unskilled operators. These methods had been previously validated against invasive ICP measurements in neurosurgery patients. The two methods concurred in their estimation of ICP changes with microgravity, i.e., 11.0 ± 7.7 mmHg for the acoustic method ( n = 7 subjects with valid results out of 30, auditory responses being masked by excessive in-flight noise in 23 subjects) and 11.3 ± 10.6 mmHg for the electric method ( n = 10 subjects with valid results out of 10 tested despite the in-flight noise). These results agree with recent publications using invasive access to cerebrospinal fluid in parabolic flights and suggest that acute microgravity has a moderate average effect on ICP, similar to body tilt from upright to supine, yet with some subjects undergoing large effects whereas others seem immune. The electric in-ear method would be suitable for ICP monitoring in circumstances and with subjects such that invasive measurements are excluded. NEW & NOTEWORTHY In-ear detectors of intracranial pressure-dependent auditory responses allow intracranial pressure to be monitored noninvasively during acute microgravity. The average pressure increase during 20-s long sessions in microgravity is 11 mmHg, comparable with an effect of body tilt. However, intersubject variability is large, with subjects who repeatedly experience from nothing to twice the average effect. A systematic in-flight use would allow the relationship between space adaptation syndrome and ICP to be established or dismissed.

Adjustments During the First few Days

Everything is different in space, so travelers will need to learn to use their muscles again, to live through the nausea of Space Adaptation Syndrome, and to adjust to their bodies changing shape and length.

Sickness induced by head movements after different centrifugal Gx-loads and durations

It has been found that sustained centrifugation on Earth may evoke sickness symptoms that are similar to those of the Space Adaptation Syndrome (SAS). As in SAS, incidence of this 'Sickness Induced by Centrifugation' (SIC) is about 50% and the symptoms are particularly evoked by head movements. By systematically varying the G-load and duration of centrifugation, the current study investigated the characteristics of the gravitational stimulus that is required for SIC to occur. Subjects were exposed to centrifugation at 2 and 3Gx, for a duration of 45 and 90 minutes. A standardized head movement protocol was used to evoke SIC after centrifugation. The results show that in six out of 12 subjects (50%) no serious symptoms were elicited. In the remaining subjects, the effects of the 3G runs exceeded those of the 2G runs, and within each G-level symptom intensity was higher for the 90 min than for the 45 min exposure. An exponential fit on this data showed that the time constant of adaptation to the gravitational stimulus was about 60 minutes. This suggests that short duration exposures (i.e. < 60 min) are not likely to induce serious SIC.