severe hypobaric hypoxia
Recently Published Documents


TOTAL DOCUMENTS

23
(FIVE YEARS 2)

H-INDEX

9
(FIVE YEARS 0)

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Fei-Fei Wu ◽  
Kun-Long Zhang ◽  
Zheng-Mei Wang ◽  
Yi Yang ◽  
Shao-Hua Li ◽  
...  

AbstractSimulated hypobaric hypoxia (SHH) training has been used to enhance running performance. However, no studies have evaluated the effects of a single SHH exposure on healthy mice performance and analyzed the changes of mitochondria-related genes in the central nervous system. The current study used a mouse decompression chamber to simulate mild hypobaric hypoxia at the high altitude of 5000 m or severe hypobaric hypoxia at 8000 m for 16 h (SHH5000 & SHH8000, respectively). Then, the mouse behavioral tests were recorded by a modified Noldus video tracking. Third, the effects of SHH on 8 mitochondria-related genes of Drp1, Mfn1, Mfn2, Opa1, TFAM, SGK1, UCP2 and UCP4, were assessed in cerebellum, hippocampus and gastrocnemius muscles. The results have shown that a single mild or severe HH improves healthy mice performance. In cerebellum, 6 of all 8 detected genes (except Mfn2 and UCP4) did not change after SHH. In hippocampus, all detected genes did not change after SHH. In muscles, 7 of all 8 detected genes (except Opa1) did not change after SHH. The present study has indicated the benefit of a single SHH in healthy mice performance, which would due to the stabilized mitochondria against a mild stress state.


2020 ◽  
Vol 14 (1) ◽  
pp. 36-42
Author(s):  
O. V. Vetrovoy ◽  
E. I. Tyulkova ◽  
V. A. Stratilov ◽  
K. A. Baranova ◽  
M. O. Samoilov

2019 ◽  
Vol 20 (5) ◽  
pp. 711-722 ◽  
Author(s):  
Eda Ağaşcıoğlu ◽  
Rıdvan Çolak ◽  
Haydar Demirel ◽  
Ufuk Çakatay

2017 ◽  
Vol 88 (7) ◽  
pp. 617-626 ◽  
Author(s):  
Jeremy M. A. Beer ◽  
Barry S. Shender ◽  
Daren Chauvin ◽  
Todd S. Dart ◽  
Joseph Fischer

SpringerPlus ◽  
2015 ◽  
Vol 4 (S1) ◽  
Author(s):  
Sergei Alexandrovich Stroev ◽  
Tatiana Sergeevna Glushchenko ◽  
Ekaterina Iosifovna Tjul’kova ◽  
Mikhail Olegovich Samoilov

2012 ◽  
Vol 72 (4) ◽  
pp. 364-373 ◽  
Author(s):  
Elena Rybnikova ◽  
Tatjana Gluschenko ◽  
Anasthasia Galeeva ◽  
Ekaterina Tulkova ◽  
Natalia N. Nalivaeva ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document