Correlation between Renal Artery Anatomy and Hypertension: A Retrospective Analysis of 3000 Patients

Objective. To assess the correlation between renal artery anatomy and blood pressure in Undiagnosed Hypertension and Diagnosed Hypertension. Methods. The renal artery CT scanning imaging data and laboratory data of 3000 inpatients and outpatients were collected retrospectively in 4 centers of China. Morphometric parameters were assessed using the quantitative vascular analysis (unit: mM). Results. 687 cases (23.2%) had accessory renal arteries unilaterally, and 216 cases (7.3%) had bilateral accessory renal arteries, including left kidney 825 (27.9%) and right kidney 798 (27.0%). The presence of accessory renal arteries and renal artery branches was higher in the diagnosed hypertension group as compared with the undiagnosed hypertension group (MARB, p p < 0.001; ARA, p < 0.001; others, p < 0.001). Consequently, multivariate regression analysis showed that age (OR = 2.519 (95% CI: 0.990–6.411, p < 0.001)), dyslipidemia (OR = 1.187 (95% CI: 0.960–1.454, p = 0.007)), renal hilum Outside the main renal artery branch (MRAB) (OR = 2.069 (95% CI: 1.614–2.524, p = 0.002)), and accessory renal artery (ARA) (OR = 2.071 (95% CI: 1.614–2.634, p = 0.001)) were risk factors of hypertension. In addition, higher renin activity was associated with ARA patients (2.19 ± 2.91 vs. 1.75 ± 2.85, p < 0.001). Conclusions. When comparing renal arteries side by side, the anatomical length of the renal arteries is significantly different. In addition, the prevalence of accessory renal arteries and renal artery branches is higher in the hypertension group. The auxiliary renal artery and the main renal artery branch outside the renal portal are independent factors of hypertension. Renal sympathetic nerve activity is affected by renin activity and is related to the accessory renal artery.

Undiagnosed Hypertension and Its Associated Factors Among Adult People Living in Southern Ethiopia: Discovery From Gunchire Woreda of Gurage Zone

Background: Hypertension is defined as two or more readings of systolic blood pressure measurement of 130 mm Hg or higher or diastolic blood pressure measurement of 80 mm Hg or higher. Symptoms of hypertension (HTN) are often not detectable at early stages and because of this many people with the disease are mostly left undiagnosed. Undiagnosed HTN is the one that increases the risk of complications such as renal failure, heart failure, myocardial infarction, stroke and premature death. There is no report concerning undiagnosed hypertension in the area. This study is aimed to assess prevalence of undiagnosed hypertension and its associated factors among adult peoples.Method: Community based Cross-sectional study design was conducted. English version questionnaire was used to collect data from 574 households. The data was collected and analyzed by SPSS version.23. The association between dependent and independent variables was tested by using multivariate regression at P-value less than 0.05 and 95% CI.Result: Out of 590 participants, 108 (18.8%) respondents were cigarette smokers and 143 (24.9%) were khat chewers. About 106 (18.5%) of respondents have sedentary lifestyle. A total of 260 (45.3%) of respondents were identified as having undiagnosed hypertension. Respondents having sedentary life style had about 2.24 time’s higher risk of undiagnosed HTN than those who didn’t have sedentary life style. BMI, sedentary life style, cigarettes smoking, health seeking behavior, dietary habit and monthly income were significant predictors of undiagnosed HTN.Conclusion: Based on the identified high prevalence of undiagnosed hypertension, the finding suggests awareness creation for community members about undiagnosed hypertension, its symptoms and ways of managing it.

How Well Does Body Mass Index (BMI) Predict Undiagnosed Hypertension and Diabetes in Indonesian Adults Community Population?

BACKGROUND: Previous studies have reported that Body Mass Index (BMI) cut-off was related to non-communicable diseases. This study aimed to give the latest evidence related to the accuracy of BMI cut-off towards undiagnosed hypertension and diabetes in the Indonesian population. METHODS: This was A cross-sectional study that involved data of the 2018 national population-based health survey, with the samples were 15,516 male and female populations aged between 19 years old and above. This study only included those claimed to have never been diagnosed as suffering from diabetes and hypertension by health workers. Receiver operating characteristic (ROC) analysis was conducted to assess the optimal BMI cut-off. The logistic regression was performed to assess the association of BMI on undiagnosed hypertension and diabetes controlled by several variables. RESULTS: The average BMI sample was 24 kg/m2 (SD = 4.6 kg/m2. The proportion of undiagnosed hypertension was 36.9%, and 12.3% for the proportion of undiagnosed diabetes. According to the ROC, the result shows BMI was more sensitive to hypertension conditions compared to diabetes. BMI cut-off points at 23.9 kg/m2 (AUC=0.59;Se=64.3%;Sp=53.4%) was the optimum value to predict hypertension and 24.9 kg/m2 (AUC=0.55;Se=53.1%;Sp=56.4%) was the optimum for diabetes. CONCLUSIONS: Based on the optimal AUC cut-off points for BMI which is around 0.5, BMI needs to be reconsidered as an anthropometric index in predicting undiagnosed hypertension and diabetes. And an assessment can be made using other anthropometric indices, such as waist circumference to predict undiagnosed hypertension and diabetes.

Abstract P164: Risk Factors Of Undiagnosed Diabetes And Hypertension In Arkansas

Introduction: Hypertension and diabetes are issues in the US especially in the south. In Arkansas, an estimated 797,000 adults have prediabetes and are at risk for diabetes. We aimed to assess cardiometabolic risk factors and impact of nutrition-related indicators in self-identified diabetes and hypertension patients and those at risk. Method: Data were analyzed from the 2008 Arkansas Cardiovascular Health Examination Survey (n=1,383), which used probability sampling to obtain a representative sample of Arkansas residents. A self-report survey was administered on health history, socioeconomic status (SES), lifestyle, and diet. Blood biomarkers were measured and compared for those who self-reported diabetes or hypertension with those who were at risk. Results: We used t-tests for continuous variables and chi-square test for categorical variables with statistical significance at p<0.05. We hypothesized that participants with undiagnosed diabetes or hypertension had less access to care (SES as a surrogate) and worse health behavior than the diagnosed groups. Significant differences in SES, behaviors, nutrients, and biomarkers were observed between healthy vs. both diagnosed and undiagnosed groups. Surprisingly, we found that undiagnosed groups had higher average food security than the diagnosed groups. Also, some of the health behaviors including alcohol consumption were 5-6 fold higher among the undiagnosed and healthy groups as compared to currently diagnosed diabetes group. Moderate physical activity was about 2 fold higher among the healthy (5.5 hours/week) as compared to undiagnosed hypertension group (3 hours/week). In addition, the currently diagnosed groups seem to have some improved dietary habits based on higher levels of vegetable and fruit consumption and lower blood cholesterol. We have also found that both the healthy and undiagnosed diabetes groups had above normal or high triglyceride levels. Conclusion: Undiagnosed diabetes and hypertension do not have serious symptoms, but are dangerous health conditions. From our findings, targeted education should be implemented among all people, especially on access to food, vegetable and fruit consumption, alcohol use, physical activity, cholesterol and triglyceride levels.

Undiagnosed Hypertension in a Workplace: The Case of a Logistics Company in Gauteng, South Africa

A large proportion of the population with hypertension remains undiagnosed, untreated, or inadequately treated, contributing to the rising burden of cardiovascular diseases in South Africa. A workplace may either mitigate or accentuate the risk factors for hypertension. A cross sectional study was conducted to determine the prevalence of undiagnosed hypertension and associated factors among 312 employees in a Logistics Company, South Africa. A modified, validated, self-administered WHO STEPwise questionnaire was used to collect data on demography, lifestyle factors, anthropometry and blood pressure (BP). Hypertension was defined at BP ≥ 140/90 mmHg. Data was analysed using STATA 14. Mean age of employees was 40 ± 10 years, with a 50% prevalence of undiagnosed hypertension. No significant association was observed between occupation and undiagnosed hypertension, except for high prevalence of undiagnosed hypertension among truck drivers and van assistants (43%), and general workers (27%), having higher odds of increased waist-to-height ratio. Hypertension was associated with age (OR = 2.3, 95%CI; 1.21–4.27), alcohol use (AOR = 1.8, 95%CI; 1.05–2.93), waist circumference (AOR = 2.3, 95%CI; 1.29–4.07) and waist-to-height-ratio (AOR = 3.7, 95%CI; 1.85–7.30). Improved and effective workplace health programs and policies are necessary for management of undiagnosed hypertension among employees. Longitudinal studies on mediation of occupation in association of demographic and lifestyle factors with hypertension in workplaces are needed.

Evaluation of Present Status of Hypertension at Port City Chattogram, Bangladesh: A Survey Study

Hypertension is one of the most common Non-Communicable Diseases, which is increasing day by day, and its complications account for 9.4 million annual deaths worldwide. The rate of hypertension in Chattogram is relatively higher and majority are undiagnosed hypertension. This study was conducted to investigate the risk factors of hypertension on the population of Chattogram and to determine the complication of Hypertension. This survey study was carried out from June 2019 to December 2019. From the survey, it was found that about 49% of people have hypertension in age between 20-49, 43% people have in age between 50-79, about 12% people have in age above 80, and majority of population have hypertension in age between 20-49. Among them, about 46% of male are suffered fromhypertension whereasfemale are 57%. Hence, the risk of hypertension is higherin female rather than in male. About 50% of people have systolic blood pressure range above 130, 38% people have above 160, 10 people have above 180 & 6% people have above 100. About 44% of people have blood relative with hypertension, about 35% people do not have & about 24% people do not aware of the relative with hypertension. Among them about 21% people are given metformin for the treatment of diabetes mellitus in hypertension & about 10% people are given both metformin & glibenclamide. About 54% of people are given Enalapril, 33% people are given Amlodipine, 7% people are given both enalapril & Amlodipine and 5% people are given hydrochlorothiazide. Compliance with treatment was relatively high; however, accessessibilty of drugs was mainly from private pharmacies. Hypertension was significantly associated with increasing age, being male, unemployment and obesity.