Pebbles on the Beach of the “Great Transformation”: Lesser Memories of Coal in the Ruhr Metropolis

Six decades ago, Germany’s Ruhr region began its slow transition out of coalmining and the coal-powered iron and steel industry. Over the last twenty years a blue economy has developed in their stead pivoting on the lead market ‘resource efficiency’, while the Ruhr Metropolis has gained recognition for the rehabilitation of its heavily polluted environment. This managed transition has seen the rise of eco-industries – sustainable energy production, research and development in universities, environmental technology companies, industrial heritage and nature tourism, as well as consumptive industries seen as eco-adjacent, foremost sports, leisure, arts and culture. These are central to an overarching strategy for the establishment of a sustainable, climate-resilient and future-proof Ruhr region and a globally significant investment site in the heart of Europe.

SUSTAINABLE INNOVATION TYPES: A BIBLIOMETRIC REVIEW

The synonymic use of sustainable innovation types obstructs the impact of increasingly disperse research on sustainable innovation, environmental innovation, eco-innovation, and green innovation. To identify the meaning and contributions of each innovation type over time, we apply co-word analysis as a bibliometric technique to 1,985 papers, analysing the evolution of motor, emergent and basic themes for each type. For environmental innovation, the focus has shifted from environmental regulations and policies to patents and inventions with an environmental impact, while in sustainable innovations the societal impact of technology adoption has become a driver. Green innovation increasingly concerns environmental technology and its management, whereas eco-innovation studies aspects related to efficiency and decision making. Clear distinctions among sustainable innovation types will increase the impact of this expanding body of research and make it more available to managers and policymakers.

Potential Development of Digital Environmental Surveillance System in Dengue Control: A Qualitative Study

Background: The development of digital environmental technology can be conducted to implement reports, surveillance, and manage dengue control. Therefore, this study aims to determine the barriers to the use of paper-based and the potential development of digital environmental technology in dengue control. Methods In-depth qualitative interviews were conducted using 14 key informants and four focus group discussions (FGD) from May-August 2021 in Denpasar City, Bali. The interviews were consistent with the flow of the epidemiological and entomological surveillance system, the obstacles to the dengue control program, the potential for the application of digital technology, and the challenges in the application of digital surveillance technology. Furthermore, open-ended questions and content analysis by qualitative study procedures were adopted. The results were transcribed verbatim and triangulation of sources was conducted for data validation. Results The reporting system that used paper-based was not optimally implemented due to repetition of reporting, speed of information, data bias, performance measurement as well as case surveillance and reporting system constraints. An integrated digital environmental surveillance system (SILIRA) was also developed for dengue control. In the current Covid-19 pandemic, the need for digital applications is high due to the policy of not accepting guests and keeping a distance. Epidemiological surveillance for case data collection, entomological surveillance for larva density, case reporting, and educational videos are the required data in the application. Conclusion The development of an integrated application for an environmental monitoring system can be created for the continuous reporting of case information and larval density for dengue hemorrhagic fever control. Keywords: digital, surveillance, environment, dengue

A Field Study for Sustainable Community Empowerment through Appropriate Technology of Water Purification and the Concept of Feces Standard Money in Hatphain Village, Lao PDR

The application of appropriate technologies in a developing country is an opportunity to introduce green technology which may lead people to imagine a better life. This point is at the intersection of appropriate technology and sustainable development. This research focuses on Hatphain village where there is no clean water, sewage system, or power lines. Two environmental technologies (an unpowered water purification system, Ongdalsaem and an eco-toilet system, BeeVi toilet) were introduced, based on the concepts of the environmental self- sustainable village and feces Standard Money (fSM). We found that the Ongdalsaem was effective in reducing the concentration of nitrogen and lead in the water in Hatphain. The BeeVi water-free toilet was installed, allowing urine and feces to be separated and used as compost. We strived to spread ideas of sustainability using new eco-circulation experiences and encouraging learning about environmental technology through practical and playing facilities that residents managed themselves.

PERSPECTIVE INSIGHT AND APPLICATION OF IN-SILICO TOOL AS VIRTUAL SCREENING METHOD FOR LEAD DESIGNING AND DEVELOPMENT

Humans are now in a bioinformatics and chemo informatics century, where we can foresee data across domains like as healthcare, the environmental, technology, and public health. The use of information sharing in silico methodologies has impacted sickness administration by predicting the absorption, distribution, metabolism, excretion, and toxicity (ADMET) patterns of synthetic compounds and efficient and environmentally succeeding pharmaceuticals upfront. The purpose of lead discovery and design is to create the appearance of novel drug candidates that can attach to a specific illness cause. The lead investigative process starts with the recognition of the lead structure, which is followed by the synthesis of its analogs and their estimation in order to produce a candidate for lead improvement. The finding of the proper lead exact is the fundamental and primary worked in the traditional lead discovery progression, and the use of computer (in silico) approaches is widely used in lead innovation. A medicinal chemist's passion for building lead structure is piqued by biomolecules, which are often made up of DNA, RNA, and proteins (such as enzymes, receptors, transporters, and ion channels). The underlying principle of such nuts and bolts is noteworthy to be acquainted with their pharmacological implication to the disease under examination. The motive of this review piece of writing is to emphasize several of the in silico methods that are used in lead discovery and to express the applications of these computational methods.

Application of some graphene derivatives to increase the efficiency of stem cell therapy

: Graphene and its derivatives have application potential in many areas such as environmental technology, catalysis, biomedicine, and in particular, stem cell-based differentiation and regenerative therapies. Mesenchymal stem cell transplantation has emerged as a potential therapy for some diseases, such as acute kidney damage, liver failure and myocardial infarction. However, the poor survival of transplanted stem cells in such applications has significantly limited their therapeutic effectiveness. Graphene-based materials can improve the therapeutic efficacy of stem cells as they prevent the death of implanted cells by attaching them prior to implantation and increasing their paracrine secretion. In this review, we will highlight a number of recent studies that have investigated the potential use of graphene or its derivatives in stem cell applications and the prevention of transplanted stem cells from cell death, thereby improving their therapeutic efficacy.