Case Report Of Adenocarcinoma On Palpebral Of Rotweiler Dog: A Histopathological Evaluation

Eyelid neoplasms cases are the most frequently recorded ophthalmic tumors in dogs, which mostly benign and only few are reported as being malignant. Adenocarcinoma is one of malignant tumor reported in dog eyes beside fibrosarcoma, squamous cell carcinoma, and hemangiosarcoma. A case of adenocarcinoma in palpebral of a 6-year-old male rotweiller dog with 6month history of a progressive mass on the left eye was presented. Pathological examination showed a severe exophytic irregular pink to red cauliflower-like mass occupying all surface of the eye lid. A transpalpebral enucleation was performed to collect the mass, followed by histopathological slide preparation using Hematoxylin-Eosin (HE) staining. Histopathological examination showed various sizes lobules separated by connective tissue. Many angioneogenesis figure were also observed. The irregular arranged of anaplastic cells was obviously seen with hyperchromatic and pleomorphic of the nuclei and various shapes and sizes of cell structures as well. There was no sign of encapsulated area, however, few mitotic figures were seen. The histopathological examination result confirmed the presence of adenocarcinoma.

COMBINED PHOTOINDUCED PATHOLOGY OF THE SKIN AND EYES IN PATIENTS WITH DERMATOHELIOSIS

Modern information on the mechanisms of the damaging effect of UV radiation on the skin and the eye is presented, constitutional phototype skin (according to the Fitzpatrick scale) and clinical stages of skin photoaging are described (according to R. Glogau). The range of clinical changes arising on the background of solar elastosis can vary depending on the anatomical site of the lesion and include a number of dermatoses included in the concept of solar elastosis syndromes, resulting in the development of malignant dermatoses. Depending on the type of UV exposure - sporadic short-term or systematic long-term, acute and chronic pathological processes caused by the action of UV may develop. The development of eyelid neoplasms (basal cell, metatypical, squamous cell carcinoma, melanoma), solar keratosis of the conjunctiva, pterygium, cataract, and macular retinal degeneration may result from the systematic UV irradiation of the organs of vision.