The presence of irrelevant alternatives paradoxically increases confidence in perceptual decisions

Confidence in perceptual decisions often reflects the probability of being correct. Hence, we predicted that confidence should be unaffected or be minimally decreased by the presence of irrelevant alternatives. To test this prediction, we designed three experiments. In Experiment 1, participants had to identify the largest geometrical shape among two or three alternatives. In the three-alternative condition, one of the shapes was much smaller than the other two, being a clearly incorrect choice. Counter-intuitively, all else being equal, confidence was higher when the irrelevant alternative was present. We accounted for this effect with a computational model where confidence increases monotonically with the number of irrelevant alternatives, a prediction we confirmed in Experiment 2. In Experiment 3, we evaluated whether this effect replicated in a categorical task, but we did not find supporting evidence. Our findings stimulate the use of multi-alternative decision-making tasks to build a thorough understanding of confidence.

Preventing music performance anxiety (MPA): Music students judge combined Depth Relaxation Music Therapy (DRMT) and silence to be an effective methodology

This article presents the results of a study which focused on the application of combined Hypnomusictherapy (HMT)/Depth Relaxation Music Therapy (DRMT) and silence in preventing music performance anxiety (MPA) in music students. Participants (n=12) were divided into two groups. Each group received either 16 minutes of HMT/DRMT followed by 6:30 minutes of silence or a 16-minute seminar consisting of a moderated group discussion on silence followed by 6:30 minutes of silence. Each of the two groups experienced the alternative condition (within-subject design) with one week in between. Focus groups were held for data gathering after each session. Qualitative content analysis according to Mayring [1,2] was applied to analyze the data. Silence following DRMT/HMT was perceived as more relaxing and longer lasting than silence following the seminar. Participants reported that their distracting or depressing thoughts decreased and their auditive perception of silence changed during the combined silence and DRMT/HMT. The results indicate that the procedure can help prevent MPA.

How the presentation of patient information and decision-support advisories influences opioid prescribing behavior: A simulation study

Objective The United States faces an opioid crisis. Integrating prescription drug monitoring programs into electronic health records offers promise to improve opioid prescribing practices. This study aimed to evaluate 2 different user interface designs for prescription drug monitoring program and electronic health record integration. Materials and Methods Twenty-four resident physicians participated in a randomized controlled experiment using 4 simulated patient cases. In the conventional condition, prescription opioid histories were presented in tabular format, and computerized clinical decision support (CDS) was provided via interruptive modal dialogs (ie, pop-ups). The alternative condition featured a graphical opioid history, a cue to visit that history, and noninterruptive CDS. Two attending pain specialists judged prescription appropriateness. Results Participants in the alternative condition wrote more appropriate prescriptions. When asked after the experiment, most participants stated that they preferred the alternative design to the conventional design. Conclusions How patient information and CDS are presented appears to have a significant influence on opioid prescribing behavior.

Non-Responsive Coeliac Disease: A Comprehensive Review from the NHS England National Centre for Refractory Coeliac Disease

Coeliac disease is a common small intestinal enteropathy which manifests following ingestion of gluten in genetically susceptible individuals. Since gluten was identified as the driving factor in coeliac disease, the gluten-free diet (GFD) has remained the mainstay of treatment. While most individuals will display improvement in symptoms and signs of coeliac disease following institution of the GFD, up to 30% will continue to experience symptoms and/or have persisting intestinal inflammation. These individuals can be classified as having non-responsive coeliac disease (NRCD), which may be associated with dietary indiscretion, slow healing, refractory coeliac disease, and/or an alternative condition. The purpose of this review is to provide an overview of the causes of NRCD in adults, highlight a systematic approach to investigate these patients, and appraise the latest management aspects of this subset of coeliac disease.

Is transcranial sonography useful for diagnosing Parkinson’s disease in clinical practice?

ABSTRACT Transcranial sonography (TCS) is an emerging ancillary examination for diagnosing Parkinson’s disease (PD). Objective To evaluate TCS features in patients with PD and its mimics, and establish their accuracy in predicting the final clinical diagnosis after follow-up. Methods We retrospectively studied 85 patients with an initial clinical suspicion of PD, atypical parkinsonism or essential tremor, all of whom underwent TCS. Two specialists reviewed the follow-up clinical visit records and determined the final clinical diagnosis. The accuracy analysis of the TCS was determined using Bayesian statistical methods. Results The finding of substantia nigra hyperechogenicity (> 20 mm2) showed high sensitivity (93.4%) and specificity (86.6%). The positive likelihood ratio showed 6.93-fold greater odds for diagnosing PD than an alternative condition when this finding was present. Conclusions This study revealed the practical usefulness of TCS in differentiating PD from its prevalent mimics when the clinical diagnosis was initially unclear.

Optimum conditions for ascorbic acid determination in three Iraqi citrus using HPLC technique

A high-performance liquid chromatography method was employed for the quantitative determination of ascorbic acid (AA) which called vitamin C in three types of Iraqi citrus (orange mandarin and aurantium ) and to establish this goal , evaluation of ascorbic acid degradation is so important due to its significant criticality when exposure to ordinary atmospheric conditions. The chromatographic analysis of AA was carried out after their sequential elution with KH2PO4 ( as mobile phase) by reverse-phase HPLC technique with C8 column and UV detection at 214 nm. .Bad resolutions was appeared clearly for C8 column , so another alternative condition were carried out to improve the resolution by replacement of C8 by C18 column .Statistical treatments were used to calculate relative standard deviation (RSD%) for the results to gain acceptable confidence to the present work , so the linearity of calibration curve, accuracy, and repeatability of this method are all satisfactory.

Control Constraint Realization for Multibody Systems

This paper discusses the problem of control constraint realization applied to generic underactuated multibody systems. The conditions for the realization are presented. Focus is placed on the tangent realization of the control constraint. An alternative condition is formulated, based on the practical observation that differential-algebraic equations need to be integrated using implicit algorithms, thus naturally leading to the solution of the problem in form of matrix pencil. The analogy with the representation of linear systems in Laplace’s domain is also discussed. The formulation is applied to the solution of simple, yet illustrative problems, related to rigid and deformable bodies. Some implications of considering deformable continua are addressed.

An Alternative Condition for Stochastic Domination

We will propose an alternative condition for stochastic domination. This condition differs in an essential way from the strong likelihood ratio property. We also show an example which satisfies the new condition, but does not satisfy the strong likelihood ratio property.

An Alternative Condition for Stochastic Domination

We will propose an alternative condition for stochastic domination. This condition differs in an essential way from the strong likelihood ratio property. We also show an example which satisfies the new condition, but does not satisfy the strong likelihood ratio property.