MO854PHYSICAL ACTIVITY IN CHRONIC HEMODIALYSIS PATIENTS: ABOUT 71 CASES

Background and Aims physical activity is generally impaired in the chronic hemodialysis patient. Studies confirm the benefit of maintaining or improving physical activity in these patients. For this reason, our study aims to assess physical inactivity in chronic hemodialysis patients using a physical activity score: DIJON score and to identify the factors linked to a decrease in physical activity . Method this is a descriptive and analytical cross-sectional study carried out at the hemodialysis center of Fattouma Bourguiba hospital in Monastir. We used the DIJON questionnaire to measure physical activity: daily activities, sports or leisure. The reference values for the level of physical activity are 0-10 (low), 10-20 (medium); and 20-30 (high). Results our study included 71 patients. The middle age was 46.62 + - 15.34 years. 69% of patients were male. The overall physical activity level was high at 22.75 + -1.99 in 28.2% of patients, medium at 13.75 + -3.65 in 33.8% of patients and low at 5.56 + -2.91 in 38% of hemodialysis patients. Analysis in multiple linear regression showed that the variables that explained the DIJON score in our population are in order of contribution: pre-dialytic uremia (β = 0.433; t = 2.99; p = 0.005), cardiac diseases(β = 0.305; t = 2.074; p = 0.044), the KT/V ratio (β = -. 858; p = -1.915; p = 0.063), the PRU (β = 1.21; t = 1.885; p = 0.066) , anemia (β = 0.211; t = 1.704; p = 0.096), comorbidity evaluated by Charlson score (β = -. 461; t = -1.414; p = 0.165). Conclusion our results showed that the level of physical activity is linked to many factors, some of which are modified. So, prescribing an adapted and personalized program will improve the prognosis and the quality of life of our patients.

Tocilizumab Use in a Chronic Hemodialysis Patient for the Management of COVID-19-Associated Pneumonia and Acute Respiratory Distress Syndrome

Novel coronavirus disease 2019 (COVID-19) is a highly infectious, rapidly spreading viral disease. As of writing this article, there are over 4.4 million people affected by COVID-19, and unfortunately, 300,000 have succumbed to the infection. In this article, we address a particularly more susceptible group of the population of end-stage renal disease (ESRD) patients on dialysis who may potentially benefit from being treated with tocilizumab. The use of tocilizumab has not been reported widely in ESRD patients on dialysis to treat COVID-19. In this case report, we describe a patient with ESRD on hemodialysis who was admitted to the intensive care unit, with severe pneumonia secondary to COVID-19 infection. This patient was treated with tocilizumab 400 mg intravenous and had a favorable outcome with no apparent adverse events.

Bilateral brachiocephalic vein stenosis in a chronic hemodialysis patient with well-functioning arteriovenous fistula – A rare entity

<b>Introduction:</b> Central vein stenosis has been reported in patients of end stage renal disease with subclavian vein being more commonly affected than brachiocephalic vein. <br><b>Case report:</b> We present a case of young female with bilateral brachiocephalic vein obstruction following arteriovenous fistula creation for hemodialysis.