Production of kombucha tea as alternative source of probiotic drink in Mandailing sub-district Tebing Tinggi City

Kombucha is a well-known health probiotic drink. Kombucha was first used in East Asia (Manchuria) in the Tsin Dynasty around 220 BC which was used for detoxification. This probiotic drink is a fresh drink from a slightly sweet, slightly acidic tea that is consumed worldwide. Kombucha tea is obtained from tea leaf infusion by fermentation with SCOBY (symbiotic culture of yeast and bacteria). The taste of the fermented tea is like apple cider vinegar. With the development of The Kombucha era, it has been studied by many researchers and provides excellent health benefits including as a source of antioxidants to prevent free radicals, antibacterial, anticancer, for diabetes, cardiovascular (heart disease), digestive problems and low body immunity because age factor. In the Mandailing sub-district, Tebing Tinggi city, there is a lack of public awareness of health. With the training in making kombucha probiotic drink, it is hoped that residents in that area can apply this health drink to improve a healthy lifestyle.

Relationship between Plasma Lipoprotein-Associated Phospholipase A2 Concentrations and Apolipoprotein in Stable Coronary Artery Disease Patients

Background. Increasing evidence states that the plasma lipoprotein-associated phospholipase A2 (Lp-PLA2) levels and apolipoprotein particles are regarded as the risk maker for cardiovascular heart disease. Nevertheless, the issue about whether Lp-PLA2 is associated with apolipoprotein particles in individuals who have been diagnosed as stable coronary artery disease (CAD) remains largely unexplored. Method. All 569 participants engaged in this research, who never took lipid-lowering drugs, had been divided into groups by the coronary angiography (CAG), namely, stable CAD: n=291; non-CAD: n=278. The results concerning Lp-PLA2 levels were calculated by Elisa Kit, while apolipoprotein particles were measured by the department of laboratory. Results. The plasma concentration of Lp-PLA2 was remarkably higher in stable CAD group than the non-CAD group (136.0±60.5 ng/mL vs. 113.2±65.6 ng/mL, P<0.001). Pearson correlation analyses explained the plasma Lp-PLA2 concentration was correlated with apoB (r=0.390, P<0.001) and apoB/apoA1 (r=0.450, P<0.001), not associated with apoA1 (r=−0.099, P=0.101). Conversely, the association remains unobserved among non-CAD patients except apoA1. Moreover, multiple linear regression revealed the relations between Lp-PLA2 concentrations and apoB (β=0.390, P<0.001), as well as apoB/apoA1 (β=0.450, P<0.001), but not apoA1 (β=−0.099, P=0.121). After adjustment for several risk factors regarding CAD, like hypertension, gender, smoking, age, and diabetes mellitus, there had still been positive associations between the Lp-PLA2 concentration and apoB (β=0.364, P<0.001), as well as apoB/apoA1 (β=0.390, P<0.001). Conclusion. The plasma levels of Lp-PLA2 provide positively a key link with apoB, apoB/apoA-1 among stable CAD, denoting the communication between Lp-PLA2 and apolipoprotein particles in the state of CAD.

Review of the Prevalence of Cardiovascular and Metabolic Comorbidities of Psoriasis

Introduction:-Psoriasis is a common disease that is linked with several other diseases. Our goals were to analyze and present literature on prevalence of various psoriatic comorbidities, and provide an estimate of what percent of psoriasis patients might have or develop Myocardial/cardiovascular/heart disease, stroke, diabetes, obesity, hypertension, or metabolic syndrome.Method:-To collect the results, we searched PubMed to identify papers that studied the frequency of the most common comorbidities of psoriasis. We used about 20. The search terms used were the particular comorbidity (or synonyms) and psoriasis. Papers were selected where the prevalence data were listed by percentages of the studied population. Prevalence data from each paper were collected and charted, and then compared. We did not use data that concerned Psoriatic Arthritis. We also recorded outliers, where frequencies did not fit with the other data found.Results:-Results for prevalence of myocardial/cardiovascular/heart disease were mixed, varying by age and severity of disease. There are few papers on prevalence of stroke, but our review suggests risk of stroke increases with severity of psoriasis. The prevalence of diabetes was largely between 10% and 20%. Obesity’s prevalence was mostly between 15% and 30%, while hypertension hovered around 30%, and metabolic syndrome prevalence was mostly between 27% and 50%.Conclusions:-There are many comorbidities of psoriasis. The complex interaction between cutaneous inflammation and heart disease, stroke, diabetes, hypertension and metabolic syndrome raises many questions about cause and effect or simple association.

Implementation of Artificial Fish Swarm Optimization for Cardiovascular Heart Disease

Today we are living in the digital world, with a systematic life, which may leads to many new diseases due to artificial production on agriculture, mental stress, economic and social stress too. Due to machine world, patients hearts diseases can be predict by various heart diseases detection model. There are various techniques, models and tools are predicted to find the real status of heart diseases which may have advantages and disadvantages too. This paper will try to improve the performance of the new proposed techniques which is used to determine the drawback from the existing system and overcome the drawback. The proposed techniques is used to preprocess the information and moved to the next process of selection to determine accuracy, sensitivity, specificity, precision, recall and F-measure from the dataset retrieved from three major metropolitan cities likes Chennai, Bangalore and Delhi. These proposed techniques provide the more efficient and effective with the existing system with 90% to 95%.