A case of acute yellow atrophy of the liver R. N. Stiehrn a. A. J. Hockett (The Journ. Of the Am. M. As. 1930.94, no. 25).

R. H. Stiehrn a. A. J. Hockett (The Journ. Of the Am. M. As. 1930.94, no. 25). reporting on the observed case of acute yellow atrophy of the liver, they dwell on the etiology of the disease, symptoms, age and gender of patients. The term acute liver necrosis is considered the most appropriate to the essence of the disease.

Acute yellow atrophy of the liver V. Peretz (Arch. Klin. And Exp. Med, 1922, No. 2-8: Doctor. Delo, 1922. No. 3-6)

Based on observations, over 25 cases of acute yellow atrophy of the liver in pregnant women that took place in Yekaterinburg in 1920-21. V. Peretz (Arch. Clin. And Exp. Med, 1922, No. 2-8: Doctor. Delo, 1922. No. 3-6) came to a trace, conclusions regarding this disease

Acute liver atrophy

The author observed a case of acute yellow atrophy of the liver.

Peculiarities of the course of pregnancy in women with common helminth infestations

The objective: peculiarities of pregnancy in women with common worm infestations in Baku. Materials and methods. During the period from 2015 to 2017, 152 women with common worm infestations were examined, in the gestation period from 16 to 40 weeks in the age group from 18 to 38 years. Depending on the nature of the infestation, 2 main groups were formed: the 1st main group included 84 women who had monoinvasia of helminths, and the 2nd main group included 68 women who had mixed helminth infestation. The control group consisted of 42 women who were pregnant without helminthiasis. All women were examined at 16–22, 23–29, 30–36 and 37–40 weeks of pregnancy. Helminthosis diagnostics was performed by detecting helminth eggs in faecal smears, pinworm eggs in scraping from perianal folds, and visual detection of helminth eggs or pinworms in faeces and vomit. Results. Common symptoms of early toxicosis are nausea, hypersalivation, and vomiting. A rare form of morning sickness treat dermatosis pregnant women, pregnant bronchial asthma, tetany, acute yellow atrophy of the liver, osteomalacia. Symptoms of toxicosis were evaluated in 152 pregnant women. The main symptoms of early toxicosis–nausea, hypersalivation and vomiting–were more common in pregnant women with helminthiasis than in women of the control group. In women with helminthiasis, a symptom complex similar to the manifestations of early toxicosis may persist throughout pregnancy, despite ongoing toxicosis therapy. Since persistent nausea and vomiting can be etiologically caused by helminthic-protozoic intoxication, the frequency of nausea and vomiting in different groups in the second and third trimesters was compared. In the second half of pregnancy, women with complaints of nausea and vomiting were present in all study groups, but they were more common in pregnant women with helminthiasis than in women in the control group. Conclusions. The data obtained on the more frequent manifestation of early toxicosis in pregnant women with helminthiasis and its demonstrated resistance throughout pregnancy prove that helminth infestations negatively affect the course of pregnancy. Key words: helminth-protozoal invasion, placental insufficiency, pregnancy.

Bahaya Penyakit Hepatitis Terhadap Ibu Hamil

Penyakit Hepatitis adalah peradangan pada hati karena toxin, seperti kimia, obat atau agen penyebab infeksi. Penyakit ini disebabkan oleh beberapa jenis virus yang menyerang dan menyebabkan peradangan serta merusak sel-sel organ hati manusia. Hepatitis yang berlangsung kurang dari 6 bulan disebut hepatitis akut, hepatitis yang berlangsung lebih dari 6 bulan disebut hepatitis kronis. Hepatitis diketegorikan dalam beberapa golongan, diantaranya hepatitis A, hepatitis B, hepatitis C, hepatitis D, hepatitis E, dan hepatitis G. Hepatitis juga terjadi karena infeksi virus lainnya, seperti mononukleosis itinfeksiosa, demam kuning dan infeksi Virus Mumps, Virus Rubella, Virus Cytomegalovirus, Virus Epstein-Barr, Virus Herpes. Penyebab hepatitis non – virus yang utama adalah alkohol dan obat-obatan. Pada wanita hamil kemungkinan untuk terjangkit hepatitis virus adalah sama dengan wanita tidak hamil pada umur yang sama. Kelainan hepar yang mempunyai hubungan langsung dengan peristiwa kehamilan, ialah : Acute fatty liver of pregnancy (Obstetric acute yellow-atrophy). Infeksi hepatitis virus pada kehamilan tidak berhubungan langsung dengan peristiwa kehamilan, namun tetap memerlukan penanganan khusus, mengingat penyulit-penyulit yang mungkin timbul baik untuk ibu maupun janin. Hepatitis virus sering menimbulakan jaundice pada kehamilan, dengan kemajuan pengobatan saat ini, asam ursodeoxychalic dapat mengurangi kerusakan hati, baik akut maupun kronik.

NEONATAL HEPATIC NECROSIS

Hepatic necrosis resembling acute yellow atrophy in the neonatal period appears to be rare. Five infants with this condition are described. The three patients who died shortly after birth presented chiefly with hemorrhagic phenomena, while those which survived longer were severely jaundiced. In four of the babies there were few surviving hepatocytes apart from a few giant cells. In the fifth infant there was partial hepatic necrosis. Noteworthy among the histologic features were marked hemosiderin deposition in all cases, focal calcification in one case, and nodule formation in another. Virus studies in three cases were negative. Unfortunately, the etiology of the hepatic necrosis in our patients has not been established and may well be multiple. The hepatocytic giant cells are reminiscent of those seen in "neonatal hepatitis" but this disease does not represent an etiological entity.