A SECURE STEGANOGRAPHY CREATION ALGORITHM FOR MULTIPLE FILE FORMATS

Nowadays the skin cancer has become a more dangerous and an unpredictable disease among the humans. Nearly one million of people all over the world every year are been affected by the skin cancer and left with no treatment due to the lack of early diagnosis. Besides the usual types of cancer such as the melanoma, basal cell carcinoma and squamous cell carcinoma that could be identified easily there are certain types of unusual skin cancer such as the Merkel cell skin cancer that are rare and difficult to diagnose. As the identification of the Merkel cell skin cancer at the early stage would be very useful in deciding the necessary treatment for its cure, the paper has put forward preprocessing techniques to improve the image quality to make the further image processing procedure easy in the identification of the skin cancer. The proposed method applies the combined image enhancement and the restoration (CIEIR) on the input skin lesion images and makes it more presentable with the improved quality for the further image processing steps in the identification of the normal skin and the skin affected by the Merkel cell tumor. The CIEIR is implemented in the MATLAB and the parameters such as the PSNR, SSIM and the MSE are measured.

Diagnostic confusion resulting from CD56 expression by cutaneous myeloid sarcoma

Myeloid sarcomas are tumor masses composed of aggregates of malignant myeloid precursors in extramedullary sites including the skin. We report a case of myeloid sarcoma in a patient who presented with an ear lobe mass and facial nerve paralysis. Expression of CD56 by the malignant cells led to an initial misdiagnosis as Merkel cell tumor. Comprehensive pathological evaluation confirmed the diagnosis of myeloid sarcoma with aberrant expression of CD56 and carrying the translocation t(8;21) (q22;q22). Aberrant antigen expression by cutaneous myeloid sarcomas can cause diagnostic confusion with other cutaneous neoplasms. This is especially relevant when myeloid sarcoma is the sole manifestation of acute myeloid leukemia.