headpiece domains
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scholarly journals F–actin-bundling sites are conserved in proteins with villin-type headpiece domains

2020 ◽  
Vol 31 (17) ◽  
pp. 1857-1866
Author(s):  
Sudeep P. George ◽  
Amin Esmaeilniakooshkghazi ◽  
Swati Roy ◽  
Seema Khurana
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Epithelial Cells ◽  
Mutational Analysis ◽  
Full Length ◽  
Resonance Structure ◽  
Nuclear Magnetic Resonance Structure ◽  
Renal Epithelial Cells ◽  
Headpiece Domains ◽  
Nuclear Magnetic

Villin is a major actin-bundling protein that assembles the microvilli of intestinal and renal epithelial cells. Using the nuclear magnetic resonance structure of the isolated villin and advillin headpiece proteins and mutational analysis in full-length proteins, we identify the actin-bundling site in human villin and proteins with villin-type headpiece domain.

Villin-type headpiece domains show a wide range of F-actin-binding affinities

2002 ◽  
Vol 52 (1) ◽  
pp. 9-21 ◽  
Author(s):  
D. Vardar ◽  
A. H. Chishti ◽  
B. S. Frank ◽  
E. J. Luna ◽  
A. A. Noegel ◽  
...  
Keyword(s):  
Actin Binding ◽  
Binding Affinities ◽  
Wide Range ◽  
Headpiece Domains
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