NHC-catalyzed covalent activation of heteroatoms for enantioselective reactions

Covalent activation of heteroatoms enabled by N-heterocyclic carbene (NHC) organic catalysts for enantioselective reactions is evaluated and summarized in this review.

Homogeneous Molecular Catalysis of the Electrochemical Reduction of N2O to N2: Redox vs. Chemical Catalysis.

Homogeneous electrochemical catalysis of N2O reduction to N2 is investigated with a series of organic catalysts and rhenium and manganese bipyridyl carbonyl complexes. An activation-driving force correlation is revealed with...

Enantiopure Isothiourea@Carbon-Based Support: Stacking Interactions for Recycling a Lewis Base in Asymmetric Catalysis

New procedures dedicated to the efficient reuse of chiral organic catalysts are currently in great demand. Indeed, and even if toxicity issues are less problematic than with organometallic catalysts, their...

Research Progress on the Catalytic Enantioselective Synthesis of Axially Chiral Allenes by Chiral Organocatalysts

Chiral allenes are important structural scaffolds found in many natural products and drugs, and in addition, they also serve as building blocks for many organic transformations. The conventional methods for preparing chiral allenes rely on the resolution of racemic allenes and the chirality transfer between non-racemic propargylic derivatives and nucleophilic reagents. In recent years, the synthesis of chiral allenes by asymmetric catalysis has been achieved fruitful results. Among them, enantioselective synthesis of chiral allenes with chiral organic catalysts is particularly prominent. In this paper, the research progress of enantioselective synthesis of chiral allenes catalyzed by chiral organic catalysts in recent years is reviewed, including various reaction systems and synthesis applications.