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scholarly journals Mycalamide A Shows Cytotoxic Properties and Prevents EGF-Induced Neoplastic Transformation through Inhibition of Nuclear Factors

Marine Drugs ◽  
2012 ◽  
Vol 10 (12) ◽  
pp. 1212-1224 ◽  
Author(s):  
Sergey A. Dyshlovoy ◽  
Sergey N. Fedorov ◽  
Anatoly I. Kalinovsky ◽  
Larisa K. Shubina ◽  
Carsten Bokemeyer ◽  
...  
Keyword(s):  
Neoplastic Transformation ◽  
Nuclear Factors ◽  
Mycalamide A

ChemInform Abstract: Synthesis of the Right Half of Mycalamide A. A Formal Total Synthesis.

ChemInform ◽  
2010 ◽  
Vol 26 (14) ◽  
pp. no-no
Author(s):  
T. NAKATA ◽  
H. MATSUKURA ◽  
D. JIAN ◽  
H. NAGASHIMA
Keyword(s):  
Total Synthesis ◽  
The Right ◽  
Mycalamide A

ChemInform Abstract: Total Synthesis of Mycalamide A. Further Synthetic Study of the Right Half.

ChemInform ◽  
2010 ◽  
Vol 27 (17) ◽  
pp. no-no
Author(s):  
T. NAKATA ◽  
H. FUKUI ◽  
T. NAKAGAWA ◽  
H. MATSUKURA
Keyword(s):  
Total Synthesis ◽  
The Right ◽  
Mycalamide A

ChemInform Abstract: Synthesis and Biological Activity of Artificial Analogues of Mycalamide A.

ChemInform ◽  
2010 ◽  
Vol 28 (51) ◽  
pp. no-no
Author(s):  
H. FUKUI ◽  
Y. TSUCHIYA ◽  
K. FUJITA ◽  
T. NAKAGAWA ◽  
H. KOSHINO ◽  
...  
Keyword(s):  
Biological Activity ◽  
Mycalamide A

ChemInform Abstract: Total Synthesis of Mycalamide A

ChemInform ◽  
2010 ◽  
Vol 29 (7) ◽  
pp. no-no
Author(s):  
H. FUKUI ◽  
H. MATSUKURA ◽  
T. NAKATA
Keyword(s):  
Total Synthesis ◽  
Mycalamide A

ChemInform Abstract: Total Synthesis of Mycalamide A (IX) and 7-epi-Mycalamide A (V).

ChemInform ◽  
2010 ◽  
Vol 31 (27) ◽  
pp. no-no
Author(s):  
William R. Roush ◽  
Lance A. Pfeifer
Keyword(s):  
Total Synthesis ◽  
Mycalamide A

scholarly journals Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortui

2009 ◽  
Vol 53 (12) ◽  
pp. 5010-5014 ◽  
Author(s):  
Güliz Gürel ◽  
Gregor Blaha ◽  
Thomas A. Steitz ◽  
Peter B. Moore
Keyword(s):  
Protein Synthesis ◽  
Ribosomal Subunit ◽  
Peptide Chain ◽  
Large Ribosomal Subunit ◽  
Haloarcula Marismortui ◽  
Nascent Peptide ◽  
Mycalamide A

ABSTRACT Structures have been obtained for the complexes that triacetyloleandomycin and mycalamide A form with the large ribosomal subunit of Haloarcula marismortui. Triacetyloleandomycin binds in the nascent peptide tunnel and inhibits the activity of ribosomes by blocking the growth of the nascent peptide chain. Mycalamide A binds to the E site and inhibits protein synthesis by occupying the space normally occupied by the CCA end of E-site-bound tRNAs.

Synthesis and Biological Activities of Sugar Analogues of Mycalamide A.

ChemInform ◽  
2007 ◽  
Vol 38 (19) ◽  
Author(s):  
Shunya Takahashi ◽  
Akihiro Okada ◽  
Miho Nishiwaki ◽  
Tadashi Nakata
Keyword(s):  
Biological Activities ◽  
Mycalamide A
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