Synthesis, Structure and Properties of the Grafted Peptidomimetic Polymer Brushes Based on Poly(N-methacryloyl-L-proline)

A new approach to synthesis at the aminated glass surface of novel biocompatible polymeric nanolayers consisting of poly(N-methacryloyl-L-proline) brushes has been developed. Formation of the polymer nanolayers has been realized in several stages. At the first stage, the glass surface has been modified by aminosilane (APTEC), afterwards monolayer of the peroxide-containing initiator (PI) based on pyromellitic acid has been tethered to this aminated surface. The immobilized PI has been used further for initiation of the grafting "from the surface" polymerization of N-methacryloyl-L-proline for obtaining of the peptidomimetic polymer brushes. Features of the reactions, as well as optimal conditions for performing the process are highlighted in this work. Presented here poly(N-methacryloyl-L-proline) grafted brush coatings are promising material for numerous applications in nanomedicine, especially for production of implants and systems of the controlled interaction with proteins and cells.

Effect of polymer nanolayers on tin-chalcogenide nanosheet/conductive polymer flexible composite films and their enhanced thermoelectric performance

Conductive polymer-coated tin-chalcogenide nanosheets and their flexible composite films are fabricated, and their enhanced thermoelectric performance is achieved.

Stable star polymer nanolayers and their thermoresponsiveness as a tool for controlled culture and detachment of fibroblast sheets

Star polymer nanolayers were successfully used as surfaces for fibroblast adhesion and proliferation, followed by their detachment in the form of a cell sheet, controlled by a temperature decrease.