Injectable Filler Technique for Face Lifting Based on Dissection of True Facial Ligaments

Background Strengthening weakened ligament tissues with injectable fillers to improve their supportive effect may achieve the aesthetic goal of face lifting. Objectives The aim of our study was to design an injectable technique for enhancing the true facial ligaments and dissect the ligaments to provide anatomical guidance for effective injection. Methods Six true facial ligaments were chosen as target anatomical sites for injection. Specimens were dissected, and three-dimensional images were reconstructed to confirm the exact location of each injection site and to confirm that the proposed injection routes will not cause dangerous vascular damage. A total of five patients received the injections; three-dimensional images were taken before and after the injections for comparison and clinical outcome assessments. Results The injection technique was designed to target six true facial ligaments, as follows. Site 1 targeted the temporal ligamentous adhesion region to lift the lateral ends of the eyebrows. Site 2 targeted the region of the lateral orbital thickening to lift the lateral canthus. Site 3 and site 4 targeted the zygomatic retaining ligaments and zygomatic cutaneous ligaments, respectively, to augment the soft tissues of the midface. Site 5 targeted the region of the maxillary ligament to lessen the nasolabial folds, and site 6 targeted the mandibular ligament to reduce the marionette line. Conclusions This site-specific injection technique targeting the true ligaments may lead to increased efficiency and accuracy of face rejuvenation and exert a lifting effect.

Trans-Esophageal Cardiac Ablation Using High Intensity Focused Ultrasound: A New Minimally Invasive Therapy for Treating Arrhythmias

Our research project at LabTau aims at developing a probe capable of delivering HIFU into the heart by a trans oesophageal approach for treating cardiac arrhythmia. Anatomical guidance is achieved with B-mode ultrasound imaging. The goal of the present study is to generate thermal lesion on beating heart of primate, where arrhythmia foci are present in humans, in order to prove the feasibility of the approach. Treatments will be monitored in real time with conventional and passive ultrafast elastography, and then with MRI. This original strategy for treating arrhythmia would avoid invasive insertion of catheter into the heart.