aziridine aldehyde
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A Mechanistic Model for the Aziridine Aldehyde-Driven Macrocyclization of Peptides

2018 ◽  
Vol 83 (16) ◽  
pp. 9119-9124
Author(s):  
Lee Belding ◽  
Serge Zaretsky ◽  
Andrei K. Yudin ◽  
Travis Dudding
Keyword(s):  
Mechanistic Model ◽  
Aziridine Aldehyde

Morita–Baylis–Hillman reaction of a chiral aziridine aldehyde

2018 ◽  
Vol 16 (43) ◽  
pp. 8048-8055
Author(s):  
Jaedeok Lee ◽  
Deepak Singh ◽  
Hyun-Joon Ha
Keyword(s):  
Alkyl Acrylate ◽  
Aziridine Aldehyde

The Morita–Baylis–Hillman reaction of chiral aziridine-2-carbaldehyde with alkyl acrylate was carried out under various conditions by changing bases and alcohol additives.

scholarly journals Retraction of “A Mechanistic Model for the Aziridine Aldehyde-Driven Macrocyclization of Peptides”

2017 ◽  
Vol 82 (8) ◽  
pp. 4512-4512 ◽  
Author(s):  
Lee Belding ◽  
Serge Zaretsky ◽  
Andrei K. Yudin ◽  
Travis Dudding
Keyword(s):  
Mechanistic Model ◽  
Aziridine Aldehyde

ChemInform Abstract: Synthesis of Chiral Piperazinones Using Amphoteric Aziridine Aldehyde Dimers and Functionalized Isocyanides.

ChemInform ◽  
2016 ◽  
Vol 47 (44) ◽  
Author(s):  
Niklas B. Heine ◽  
Sherif J. Kaldas ◽  
Lee Belding ◽  
Olga Shmatova ◽  
Travis Dudding ◽  
...  
Keyword(s):  
Aziridine Aldehyde

Synthesis of Chiral Piperazinones Using Amphoteric Aziridine Aldehyde Dimers and Functionalized Isocyanides

2016 ◽  
Vol 81 (12) ◽  
pp. 5209-5216 ◽  
Author(s):  
Niklas B. Heine ◽  
Sherif J. Kaldas ◽  
Lee Belding ◽  
Olga Shmatova ◽  
Travis Dudding ◽  
...  
Keyword(s):  
Aziridine Aldehyde

Solid-Phase Parallel Synthesis of Functionalised Medium-to-Large Cyclic Peptidomimetics through Three-Component Coupling Driven by Aziridine Aldehyde Dimers

2015 ◽  
Vol 21 (25) ◽  
pp. 9249-9255 ◽  
Author(s):  
Adam P. Treder ◽  
Jennifer L. Hickey ◽  
Marie-Claude J. Tremblay ◽  
Serge Zaretsky ◽  
Conor C. G. Scully ◽  
...  
Keyword(s):  
Solid Phase ◽  
Parallel Synthesis ◽  
Aziridine Aldehyde ◽  
Three Component Coupling

scholarly journals Mechanistic investigation of aziridine aldehyde-driven peptide macrocyclization: the imidoanhydride pathway

2015 ◽  
Vol 6 (10) ◽  
pp. 5446-5455 ◽  
Author(s):  
Serge Zaretsky ◽  
Jennifer L. Hickey ◽  
Joanne Tan ◽  
Dmitry Pichugin ◽  
Megan A. St. Denis ◽  
...  
Keyword(s):  
Multicomponent Reaction ◽  
Mechanistic Investigation ◽  
Aziridine Aldehyde ◽  
Aziridine Aldehydes ◽  
Amino Amides

Aziridine aldehydes participate in a multicomponent reaction with α-amino amides and isocyanides to generate reactive imidoanhydride intermediates.

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