primary malignant neoplasm
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2018 ◽  
Vol 144 (8) ◽  
pp. 727 ◽  
Author(s):  
Eric Adjei Boakye ◽  
Paula Buchanan ◽  
Leslie Hinyard ◽  
Nosayaba Osazuwa-Peters ◽  
Mario Schootman ◽  
...  

2018 ◽  
Vol 10 (1) ◽  
pp. 2018024
Author(s):  
Aya Nakaya ◽  
Shinya Fujita ◽  
Atsushi Satake ◽  
Takahisa Nakanishi ◽  
Yoshiko Azuma ◽  
...  

The correlation between human T-cell leukemia virus type І (HTLV-І) infection and malignant neoplasms other than adult T-cell lymphoma (ATL) remains unknown. We analyzed the frequency of primary malignant neoplasm in HTLV-І-seropositive patients. From January 2006 to December 2016, 203 patients were diagnosed as HTLV-І-seropositive at Kansai Medical University Hospital. Among them, 32 developed a primary malignant neoplasm. Their median age was 64 years old, 63% of them were male, and 69% of them were HTLV-I carriers. This group had the following distribution of ATL subtypes: 31% smoldering type, 0% chronic type, 3% acute type, and 3% lymphoma type. Among them, 53% was hematology malignancy, and solid tumor was 47%. The most frequent type of hematological malignancy was T-cell lymphoma (23%), followed B-cell lymphoma (16%), and myelodysplastic syndromes (6%). The most frequent primary solid tumor locations were the lung (15%), followed by the colon (9%), prostate (6%), kidney (6%), cervix (2%), breast (2%), liver (2%), pancreas (2%), and oral cavity (2%). Our results suggest that HTLV-Іinfection is often associated with the development of other malignant neoplasms. Therefore, HTLV-І-positive patients should be made aware of their increased risk for the onset of a malignant neoplasm and undergo increased surveillance.


2018 ◽  
Vol 14 (5) ◽  
pp. 999
Author(s):  
Ayush Naik ◽  
Virendra Bhandari ◽  
RY Saadvik ◽  
KL Gupta ◽  
Mehlam Kausar ◽  
...  

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