dietary uptake
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Antibiotics ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 977
Author(s):  
Traithawit Naksagoon ◽  
Shoji Takenaka ◽  
Ryoko Nagata ◽  
Maki Sotozono ◽  
Tatsuya Ohsumi ◽  
...  

This study aimed to evaluate the anticariogenic biofilm activity of a novel zinc-containing glass ionomer cement, Caredyne Restore (CR), using a flow-cell system that reproduces Stephan responses. Streptococcus mutans biofilms were cultured on either CR or hydroxyapatite (HA) discs mounted on a modified Robbins device. The media were allowed to flow at a speed of 2 mL/min for 24 h while exposed to an acidic buffer twice for 30 min to mimic dietary uptake. Acid exposure enhanced biofilm inhibition in the CR group, which showed 2.6 log CFU/mm2 in viable cells and a 2 log copies/mL reduction in total cells compared to the untreated group after 24 h of incubation, suggesting enhanced anticariogenic activity due to the release of fluoride and zinc ions. However, there was no difference in the number of viable and total cells between the two experimental groups after 24 h of incubation in the absence of an acidic environment. The anticariogenic biofilm activity of CR occurs in acidic oral environments, for example in the transient pH drop following dietary uptake. CR restorations are recommended in patients at high risk of caries due to hyposalivation, difficulty brushing, and frequent sugar intake.


2021 ◽  
Vol 757 ◽  
pp. 143779
Author(s):  
Tobias Lammel ◽  
Amalie Thit ◽  
Xianjin Cui ◽  
Catherine Mouneyrac ◽  
Anders Baun ◽  
...  

2019 ◽  
Vol 12 (3) ◽  
pp. 501-511 ◽  
Author(s):  
D. Brad Akers ◽  
Adaline Buerck ◽  
Michael F. MacCarthy ◽  
Jeffrey A. Cunningham ◽  
James R. Mihelcic

2019 ◽  
Vol 53 (8) ◽  
pp. 4274-4284 ◽  
Author(s):  
Haotian Wang ◽  
Xinghui Xia ◽  
Ran Liu ◽  
Zixuan Wang ◽  
Yawei Zhai ◽  
...  

2019 ◽  
Vol 21 (7) ◽  
pp. 1115-1131
Author(s):  
Cynthia A. de Wit ◽  
Anna-Karin Johansson ◽  
Ulla Sellström ◽  
Peter Lindberg

Mass balance study in peregrine falcons showed efficient dietary uptake, bioaccumulation, transfer to eggs of tri–decaBDE, HBCDD; metabolism also indicated.


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