PHYTOADAPTOGENS IN THE TUMOURS BIOTHERAPY AND GERIATRICS (PART 1)

The review reflects the history of phytoadaptogens studies (ginseng, eleutherococcus, etc.), which are considered to be geroprotectors by Eastern medicine for centures. They have a complex of protective effects on the body, as well as increasing its antitumor resistance. The first part of the review describes the antistress, immuno- and hormone-modulating, cognitive and neuroprotective properties of adapto gens. Together with the synchronizing effects on biorthms adaptogens are essential for preventive oncology.

CHARACTERISTICS OF ADAPTATIONAL REACTIONS AND MALIGNANT SPREAD IN TUMORS OF VARIOUS LOCATIONS

The character, intensity and quantitative indicator (QI) of general nonspecific adaptational reactions (AR) of the body were studied in patients with lung cancer (LC) or biliopancreatoduodenal cancer (BPDC) with various malignant spread. Poor AR characteristics were associated with the presence of metastases, but did not depend on the surgery volume. AR QI significantly differed depending on the metastatic status in patients with resectable LC receiving similar surgery treatment. AR QI in BPDC patients a day after radical pancreatoduodenal resection was higher than after bypass anastomosis. Thus, the studied AR characteristics demonstrated the state of systemic neuroimmune mechanisms of the nonspecific antitumor resistance of the body.