Correlation between Individual Characteristics and Work Position with Work Fatigue on Workers

Introduction: Work fatigue is a condition of decreased efficiency and resilience of workers, which can interfere the companys’ productivity. Job fatigue can be caused by the performance, duration, and effort (work position) of the workers. Based on the observations, workers at the expedition sub units of PT X needed to lift 200 to 400kg heavy loads. The activity of lifting very heavy weights can cause fatigue. One form of physical fatigue indicators is an increase in lactic acid in the blood. The purpose of this study was to analyze the correlation between workers’ characteristics and work position with work fatigue among workers in the expedition sub units of PT X. Methods: This research was a quantitative study with a cross sectional design. The population of this study was 36 people. This research used total sampling. The independent variable were individual characteristics and work position as measured using REBA tools, and the dependent variable was work fatigue as measured using lactic acid levels in blood. Data was analyzed using statistical tools to obtain the value of correlation coefficient between variables. Result: The results showed that there was a weak positive correlation between workers’ characteristics and physical fatigue. The results showed that the coefficient value between work position and physical fatigue was 0.354. The coefficient figure indicated a weak positive correlation between work position and work fatigue. Conclusion: There was a correlation between work position and work fatigue in workers.Keywords: ergonomics, lactic acid, REBA, work fatigue, work position .

The level of physical activity of university students in Slovakia during COVID - 19 pandemic

Background and Study Aim. COVID-19 coronavirus pandemic has affected several areas of human and public life. The implementation of the restrictions affects free movement, leading to limited physical activity (PA) level. The main aim of the study was to determine the level of PA of university students in Slovakia during COVID–19 pandemics. Material and Methods. The sample consisted of 3128 university students. Data was obtained from students from three universities with different specializations. A questionnaire about lifestyle with questions about physical activity was used. The questionnaire was distributed using online communication systems of universities. The online questionnaire was answered by 3128 students. Results. Analyzed data were obtained from 3128 students. The results indicate that 38% of all students exercise 3-4 times per week, while 41% exercise 1-2 times per week, and 21% do not exercise at all, or exercise 1-2 times per month. Found weak positive correlation (r=0,337) was between the exercise frequency and perception of well-being, and a very weak positive correlation (r=0,187) between the exercise frequency and stress intensity. A moderate positive correlation was found between the perception of health and life energy (r=0,579). A moderate positive correlation was observed between the perception of health and physical strength (r=0,579). Conclusions. COVID-19 restrictions have been associated with the reduction of physical activity of the students. To avoid the negative effects of a sedentary lifestyle, it is necessary to promote activity among university students.

Sensibilization Spectrum in Preschool Children with Atopic Dermatitis

Background. Atopic dermatitis (AD) is an allergodermathosis that is widespread in children and adult populations. Sensibilization to food allergens prevails in children of early age, and to airborne allergens in older age. Impairments of skin barrier lead to increase in Staphylococcus aureus colonization and finally aggravate the course of AD and the sensibilization level.Objective. The aim of the study is to estimate the sensibilization spectrum in 3-6 years old children with AD and its correlation with severity.Methods. It was cross sectional study with two independent cohorts of 3-6 years old children with and without (healthy) AD. Estimation of sensibilization spectrum and revealing of correlation with disease severity were performed.Results. The study includes 106 children aged 4.4 ± 1.2 year (58.5% boys and 41.5% girls). Polysensibilization was revealed in 28.3% of children. According to our data: 3-6 years old children with AD most often had sensibilization to the cat epithelium (34.9%), cow's milk proteins (22.6%), Dermatophagoides pteronyssinus mite (16.0%). Sensibilization to enterotoxins of Staphylococcus aureus was revealed in 7.5% children. We have recorded weak positive correlation between the AD severity and the level of specific IgE to airborne and food allergens. There was no statistically significant correlation between the AD severity and the level of specific IgE to Staphylococcus aureus enterotoxins A and B. Conclusion. The most common sensibilization type among 3-6 years old children with AD was one to airborne allergens. Sensibilization to the cat epithelium prevails among airborne allergens, to the cow's milk proteins — among food allergens. The weak positive correlation between the AD severity and the level of specific IgE to airborne and food allergens was revealed. The weak negative correlation with the level of specific IgE to Staphylococcus aureus enterotoxins A and B was revealed, thus the data was statistically insignificant.

The relation of Body Mass Index to Mechanical Properties in Normal and Overweight Individuals

Background: The study was to determine the relation of body mass index to muscular mechanical properties in normal and overweight individuals Methods: A total of 172 participants (86 males and 86 females, mean age; 26.00±5.45 years) were participated. The participants were assigned in groups base on BMI classification (normal (BMI=18.50-24.99 kg/m2), overweight (BMI=25.00-29.99 kg/m2). The biceps brachii (BB), biceps femoris (BF) were measured bilaterally using the "MyotonPRO" device. Results: Bilateral BB and BF stiffness, and BB elasticity were found significantly difference between normal and overweight group (p<0.05). Also the only left BB tone was found different (p<0.05) while other mechanical parameters found similar (p>0.05). In sex based BMI sub-categories comprasion; the bilaterally BB and BF stiffness and BF tone were found higher, and only the right BB elasticity was decreased in overweight male group (p<0.05). While the other mechanical parameters were found similar (p<0.05). The right BB stiffness and elasticity were found higher in overweight female group (p<0.05). No statistical difference was found in other parameters for female comparison (p>0.05).A weak positive correlation was found between the right-left BB tone and stiffness and BMI. Also, a weak positive correlation was revealed between the right BB elasticity (p<0.05). No correlation was determined in other mechanical paramaters (p>0.05).Conclusions: The bilateral BB and BF stiffness increased and BB elasticity decreased as BMI increased. The BB and BF mechanical properties were affected more in males than females when BMI considered.

Assessment of Knowledge, Attitude and Practice (KAP) in Tuberculosis patients

Tuberculosis (TB) is a highly contagious airborne disease caused by Mycobacterium tuberculosis that primarily affects the lungs. TB is a significant and major public health emergency globally. According to the WHO Global Tuberculosis Report 2020, 10 million people developed TB disease in the year 2019. The main objective of the study was to assess the level of knowledge, attitude and practice in TB patients. The study also reveals the association between KAP and the demographics of the subjects. An observational study was employed to collect data from a total of 71 subjects. Both quantitative and qualitative statistical analysis were adopted. From the findings, the mean age of the study population was 45.5 ± 13.96 years. Over 15.50% of subjects appeared to have adequate knowledge, 87.33% of subjects had a fair attitude, and around 58% of subjects were reported to have good practices towards TB. A weak positive correlation between knowledge and attitude (p = 0.051), weak positive correlation between knowledge and practice (p = 0.138) whereas, a significant and moderately positive correlation between attitude and practice (p = 0.002) was observed. The mean knowledge scores of graduates and post-graduates were higher in comparison with other study subjects. The study findings showed that the majority of subjects had several misconceptions about TB and hence prioritized interventions and more awareness programs at the root levels are needed to aid TB control and eradication.

EPIDEMIOLOGICAL CHARACTERISTICS OF LEPTOSPIROSIS IN VOJVODINA, SERBIA, 2009-2018, FROM THE ASPECT OF ONE HEALTH

This study attempts to summarize epidemiological characteristics of human leptospirosis and to determine the seroprevalence of this disease among domestic animals in the Autonomous Province of Vojvodina, for the period 2009-2018. Chronological, demographic and topographic characteristics of human cases were analyzed. Pearson's correlation was used to explore correlations between different meteorological factors and trends in time-series of human cases. Overall 87 human cases of leptospirosis and five subsequent deaths (CFR: 5.75%) were recorded in the ten-year period. The average annual incidence rate was 0.45/100,000 (range: 0.16-1.50/100,000). The disease was more prevalent in males (M/F=16.40:1), with the majority of cases reported in August (N=23; 26.44%), September (N=20; 23.00%) and October (N=15; 17,24%). A statistically significant weak positive correlation was observed between the mean monthly air temperature and the number of human cases of leptospirosis of the same month (r=0.30, p<0.01) and a statistically significant weak positive correlation was found between the number of human cases and the sum of precipitation in the previous month (r=0.27, p<0.01). The average annual seroprevalence among domestic animals in total was 1.13% (range: 0.23% -3.65%). Seropositivity of tested samples of cats, dogs, cattle, donkeys, horses, sheep, pigs and goats was 25%, 9.50%, 8.55%, 6.25%, 1.59%, 0.25%, 0.18%, 0.00, respectively. Human and animal leptospirosis continuously occurs in Vojvodina, which implies the need for continuous and quality monitoring of the epidemiological and epizootiological situation of this disease. Further, more comprehensive parallel studies in humans and animals are needed, as well as additional studies of living conditions of animals on farms with leptospirosis and the studies that will determine the strength of association between climatic/ environmental factors and leptospirosis in Vojvodina. Key words: Human leptospirosis, animal leptospirosis, zoonosis, epidemiology, seroprevalence, one health.

618 Management of Rectal Cancer in England And Wales. Is the Rate of Abdominoperineal Excision of Rectum Associated with The Pre-Operative Radiotherapy Rates?

Aim Rectal cancer treatment has improved over the years, but variations in practice remain. Abdominoperineal resection (APER) is associated with significant morbidity and pre-operative radiotherapy (RT) is only recommended for advanced rectal cancer. As such, APER and RT should be reserved for patients with an appropriate clinical need. The aim of the study is to evaluate the association between the rates of APER and RT, and whether any other factors are associated. Method Data on rectal cancer cases was extracted from National Bowel Cancer Audit 2019. Primary outcomes were: APER rate, RT rate. Pearson’s correlation coefficient was calculated. The means for APER and pre-operative radiotherapy were plotted on a four-quadrant matrix. The differences were analysed using Mann-Whitney U and Student T-test. Results 3,764 patients were included. A mean of 25% (95%CI: 10.3-14.9%) underwent APER and an average of 34% (95%CI: 30.5-36.8%) received RT. There was a weak positive correlation between rates of APER and RT (r = 0.356, p &lt; 0.001). 43 (37%) trusts had proportions of both APER and RT below the overall mean, whilst 30 (26%) had both proportions above. No significant differences were found when comparing other variables between the high to low-rate trusts (p &gt; 0.05). Conclusions There is a weak positive correlation between the proportion of rectal cancer patients undergoing APER and the proportion receiving RT in trusts across England and Wales. It is unknown whether this finding has a clinical significance and further analysis on trust/surgeon performance and patient demographics is needed, allowing for prevention strategies to be implemented.

Correlation of Waist Circumference with Monocyte Lymphocyte Ratio, Hemoglobin, and Hba1c in Obesity

Background: Obesity is a condition of excessive BMI, accompanied by accumulation of abnormal fat, especially visceral fat. Visceral fat accumulation can be known by measuring waist circumference. Chronic inflammation in obesity, especially central obesity can cause insulin resistance. Monocyte lymphocyte ratio (MLR) is one of the inflammatory markers that is cheap and easy to examine. Anemia can be caused by chronic inflammatory in obesity and interfere by quality of life, activity, and nutrition. HbA1c as one of the glucose parameters can increase because of insulin resistance. Method: Cross-sectional study of 46 obese young adults, based on WHO criteria during May-September 2018 was done. MLR was measured by manual calculation of differential counts hematology analyzer. Hemoglobin was measured by hematology analyzer and HbA1c was measured by high performance liquid chromatography (HPLC). Pearson test was performed for analyzing data with p <0.05 was significant. Results: Waist circumference had significant weak positive correlation with MLR and HbA1c respectively (r = 0.376 p = 0.010 ; r = 0.378 p = 0.010) and waist circumference had significant moderate positive correlation with Hb (r = 0.452, p= 0.002). Conclusions: There was significant weak positive correlation between waist circumference and MLR, and HbA1c. There was significant moderate positive correlation between waist circumference and Hb in obesity. Future examination of inflammatory parameters and anemia is needed for further study Keywords: Waist circumference, MLR, Hb, and HbA1c.

P–333 Vaginal and endometrial microbiota: is there any correlation

Study question Is there any correlation between the total bacterial load and the lactobacilli quantities in the vaginal and endometrial microbiomes in reproductive-age women? Summary answer There was no correlation between the vaginal and endometrial total bacterial loads and only a weak positive correlation between the quantities of lactobacilli. What is known already The Lactobacilli-dominated microbiota is considered to be the most favorable type of microbiota in the uterine cavity. It is associated with increased reproductive success in women undergoing in vitro fertilization. Whereas the non-Lactobacillus dominated microbial communities are more frequent in women with poor pregnancy outcomes. When analyzing endometrial microbiota, one of the challenges is sampling. Transvaginal sample intake involves the possibility of contaminating the samples with vaginal microbiota. Moreover, it is an invasive procedure leading to the development of infectious inflammatory diseases of the upper genital tract. Thus, researchers are currently searching for predictors of the state of endometrial microbiota. Study design, size, duration It is a cross-sectional study of the vaginal end endometrial micorbiomes from 64 reproductive-age women. Endometrial and vaginal samples were collected simultaneously on days 7–10 of the menstrual cycle. To avoid contamination by vaginal microbiota, Endobrush Standard for Endometrial Cytology (Laboratoire C.C.D.; France) was used for endometrial sampling. Participants/materials, setting, methods The study included women who came to the “Garmonia” Medical Center (Yekaterinburg, Russia) seeking infertility treatment. The average age of the patients was 32.2±5.0. DNA from vaginal and endometrial samples was extracted using PREP-NA-PLUS kit (DNA-Technology, Russia). Vaginal and endometrial microbiota was analyzed using Femoflor real-time PCR kit and DTprime 4M1 thermocycler (DNA-Technology, Russia). Main results and the role of chance Total bacterial load (TBL) in vaginal discharge was 3.8–7.9 lg (median — 7.1, interquartile range — 6.6–7.4). TBL in the endometrial samples was 0–5.1 lg (median — 3.9, interquartile range — 3.6–4.2). There was no correlation between TBL values in vaginal discharge and endometrial samples (Spearman’s rho — 0.247, p = 0.049). Lactobacilli quantities in vaginal discharge were 4.5–8.3 lg (median — 7.2, interquartile range — 6.4–7.6), in endometrial samples — 0–5.1 lg (median — 3.7, interquartile range — 3.1–4.2). There was a weak positive correlation between lactobacilli quantities in vaginal and endometrial samples (Spearman’s rho — 0.362, p = 0.003). The proportion of lactobacilli in vaginal discharge was 1–100% (median — 100%, interquartile range — 95–100%), in the endometrial samples — 0–100% (median — 96%, interquartile range — 25–100%). There was no correlation between lactobacilli proportions in vaginal and endometrial samples (Spearman’s rho — 0.225, p = 0.074). Furthermore, there was no correlation between lactobacilli quantity in the vagina and their proportion in the endometrial microbiota (Spearman’s rho — 0.294, p = 0.018). There was only a weak positive correlation between the quantities of lactobacilli in vaginal and endometrial samples. Vaginal TBL values and lactobacilli proportions did not correlate with lactobacilli quantities and proportions in the endometrial samples. Limitations, reasons for caution The study was conducted on a small sample. Moreover, it is notoriously difficult to interpret the analysis results for endometrial microbiota due to the high risk of contamination and its low microbial biomass. Wider implications of the findxings: Apparently, there is no obvious link between the vaginal and endometrial microbiomes. It is possible that, apart from vaginal microbiota, there are other predictors which could allow us to assume whether lactobacilli are present in the endometrial microbiota. Trial registration number Not applicable

Occupational Stress and Psychological Health of Employees of University Libraries in Osun State, Nigeria

This study examined the influence of occupational stress on the psychological health of the employees of university libraries in Osun State, Nigeria. A random sample of 32 participants from selected university libraries in Osun State, Nigeria. The result of the hypothesis revealed a weak positive correlation between occupational stressors and psychological health status (N = 32, r = 0.427, p = 0.015). The test also shows a weak positive correlation between the level of occupational stress and psychological health status (N = 32, r = 0.493, p = 0.004). The study concluded that employees who do not experience work-related stress would enjoy good health. The study also recommended that the management of university libraries should ensure that they provide mentorship, funds, Internet facilities, and encouragement to their employees to ensure a stress-free work environment so that library employees would continue to enjoy good health.