receptor mosaics
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The changing world of G protein-coupled receptors: from monomers to dimers and receptor mosaics with allosteric receptor–receptor interactions

2010 ◽  
Vol 30 (5) ◽  
pp. 272-283 ◽  
Author(s):  
Kjell Fuxe ◽  
Daniel Marcellino ◽  
Dasiel Oscar Borroto-Escuela ◽  
Malgorzata Frankowska ◽  
Luca Ferraro ◽  
...  
Keyword(s):  
G Protein ◽  
G Protein Coupled Receptors ◽  
Receptor Mosaics ◽  
Receptor Interactions ◽  
G Protein Coupled ◽  
Changing World

An integrated view on the role of receptor mosaics at perisynaptic level: focus on adenosine A2A, dopamine D2, cannabinoid CB1, and metabotropic glutamate mGlu5receptors

2010 ◽  
Vol 30 (5) ◽  
pp. 355-369 ◽  
Author(s):  
Luigi F. Agnati ◽  
Diego Guidolin ◽  
Giovanna Albertin ◽  
Elena Trivello ◽  
Francisco Ciruela ◽  
...  
Keyword(s):  
Metabotropic Glutamate ◽  
Receptor Mosaics ◽  
Dopamine D2 ◽  
Adenosine A2a

scholarly journals On the expanding terminology in the GPCR field: The meaning of receptor mosaics and receptor heteromers

2010 ◽  
Vol 30 (5) ◽  
pp. 287-303 ◽  
Author(s):  
Luigi F. Agnati ◽  
Diego Guidolin ◽  
Jean Pierre Vilardaga ◽  
Francisco Ciruela ◽  
Kjell Fuxe
Keyword(s):  
Receptor Mosaics ◽  
Receptor Heteromers

scholarly journals Theoretical Considerations on the Topological Organization of Receptor Mosaics

2009 ◽  
Vol 10 (6) ◽  
pp. 559-569 ◽  
Author(s):  
Luigi Agnati ◽  
Kjell Fuxe ◽  
Amina Woods ◽  
Susanna Genedani ◽  
Diego Guidolin
Keyword(s):  
Receptor Mosaics ◽  
Topological Organization ◽  
Theoretical Considerations

scholarly journals Integrated signaling in heterodimers and receptor mosaics of different types of GPCRs of the forebrain: relevance for schizophrenia

2009 ◽  
Vol 116 (8) ◽  
pp. 923-939 ◽  
Author(s):  
Kjell Fuxe ◽  
Daniel Marcellino ◽  
Amina S. Woods ◽  
Leo Giuseppina ◽  
Tiziana Antonelli ◽  
...  
Keyword(s):  
Receptor Mosaics ◽  
Different Types

Heterodimers and Receptor Mosaics of Different Types of G-Protein-Coupled Receptors

Physiology ◽  
2008 ◽  
Vol 23 (6) ◽  
pp. 322-332 ◽  
Author(s):  
Kjell Fuxe ◽  
Daniel Marcellino ◽  
Diego Guidolin ◽  
Amina S. Woods ◽  
Luigi F. Agnati
Keyword(s):  
Drug Development ◽  
G Protein ◽  
Research Area ◽  
G Protein Coupled Receptors ◽  
Major Research ◽  
Receptor Mosaics ◽  
Different Types ◽  
Allosteric Mechanisms ◽  
Novel Drug ◽  
G Protein Coupled

Through an assembly of interacting GPCRs, heterodimers and high-order heteromers (termed receptor mosaics) are formed and lead to changes in the agonist recognition, signaling, and trafficking of participating receptors via allosteric mechanisms, sometimes involving the appearance of cooperativity. This field has now become a major research area, and this review deals with their physiology being integrators of receptor signaling in the CNS and their use as targets for novel drug development based on their unique pharmacology.

Receptor mosaics of neural and immune communication: Possible implications for basal ganglia functions

2008 ◽  
Vol 58 (2) ◽  
pp. 400-414 ◽  
Author(s):  
Luigi F. Agnati ◽  
Kjell G. Fuxe ◽  
Larisa B. Goncharova ◽  
Alexander O. Tarakanov
Keyword(s):  
Basal Ganglia ◽  
Receptor Mosaics

Receptor–receptor interactions within receptor mosaics. Impact on neuropsychopharmacology

2008 ◽  
Vol 58 (2) ◽  
pp. 415-452 ◽  
Author(s):  
K. Fuxe ◽  
D. Marcellino ◽  
A. Rivera ◽  
Z. Diaz-Cabiale ◽  
M. Filip ◽  
...  
Keyword(s):  
Receptor Mosaics ◽  
Receptor Interactions
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