Localization of enterprises for primary processing of milk in Almaty region

The purpose-on the basis of the analysis of the current state and location of enterprises in the dairy industry of the republic and Almaty region, in particular, to identify the main factors that hinder its development, to develop recommendations for solving the existing problems. Methods - monographic, computational-constructive, analytical, economic-statistical, logical generalization. Results - research confirms the underdevelopment of the infrastructure for effective promotion of dairy products from producer to consumer along the production-processing-sale technological chain, especially primary milk processing; often there is a discrepancy between the required proportions between the existing production capacities of milk processing enterprises and the level of development of their raw material zones. Based on production potential of each district of a specific region and calculation of the population's demand for dairy products, a forecast for creation of agricultural cooperatives (APC) of dairy direction for purification of milk from mechanical impurities, cooling, storage and transportation in the context of districtsis presented. It is necessary to create 77 APC for the period 2021-2022, incl. 64 cooperatives for primary milk processing. Conclusions - it is recommended to merge small farms into agricultural cooperatives. The economic efficiency of organizing a cooperative milk collection point at the district level has been justified. Based on the study of the existing schemes for location of milk processing enterprises, proposals have been developed for the localization of new cooperative milk collection points in the territorial units of the region. Dairy industry enterprises need investments to renew their fixed assets. The authors note that the possibilities and advantages of cooperative principles and the potential reserve of agricultural cooperation are not yet fully realized.

TCF21+ mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice

Testicular development and function rely on interactions between somatic cells and the germline, but similar to other organs, regenerative capacity declines in aging and disease. Whether the adult testis maintains a reserve progenitor population remains uncertain. Here, we characterize a recently identified mouse testis interstitial population expressing the transcription factor Tcf21. We found that TCF21lin cells are bipotential somatic progenitors present in fetal testis and ovary, maintain adult testis homeostasis during aging, and act as potential reserve somatic progenitors following injury. In vitro, TCF21lin cells are multipotent mesenchymal progenitors which form multiple somatic lineages including Leydig and myoid cells. Additionally, TCF21+ cells resemble resident fibroblast populations reported in other organs having roles in tissue homeostasis, fibrosis, and regeneration. Our findings reveal that the testis, like other organs, maintains multipotent mesenchymal progenitors that can be potentially leveraged in development of future therapies for hypoandrogenism and/or infertility.

Mobile medicine (m-health) a potential reserve of the health care system in crisis situations as exemplified by the coronavirus epidemic COVID-19

The article discusses new opportunities to improve the quality of medical care, including for older citizens, when organizing a system of remote dynamic monitoring using methods of preventive, predictive and personalized medicine, including during the epidemic and quarantine events. Objective: to study the benefits of using mobile medicine technologies (m-health) during the fight against coronavirus infection COVID-19. The research method is the analysis and meta-analysis of publications on this topic. The results of the study show the importance of using mobile medicine technologies (m-health) in the structure of medical care for patients at risk and the particular relevance of using these technologies in the development of organizational measures to prevent and control the epidemic, caused, inter alia, by unknown infectious agents.

Seed Productivity of Coenopopulations of Tulipa Gesneriana L. (Liliaceae) on the Ergeninskaya Upland (Within the Boundaries of the Republic of Kalmykia)

This article presents results on the seed productivity of populations of Tulipa gesneriana L. in the Ergeninskaya Upland (within the boundaries of the Republic of Kalmykia). This species is listed in the Red Data Books of several regions of Russia, including Kalmykia. The research objects were 4 populations of T. gesneriana growing on the Ergeninskaya Upland, which extends across the Republic territory from north to southwest on light chestnut soils of solonetzicity. The potential seed productivity of these T. gesneriana plants was 161.8-181.5 pcs. seeds per plant; the actual seed productivity was 161.8-181.5 pcs. seeds per plant; and the formation of seeds was 34.4-75.6%. All indicators of seed productivity showed significant interpopulation differences when moving from the northern part of the Upland to its southern part. A potential reserve of mature seeds per 1 meter2 , formed during the growing season, in the coenopopulations of T. gesneriana was 253.2 - 3212.8 pcs. in 2018 and 368.0 - 1121.2 pcs. in 2017 on the Ergeninskaya Upland. Keywords: Tulipa gesneriana, coenopopulation, seed productivity, seed reserve

In-vitro activity of tigecycline and comparator agents against common pathogens: Indian experience

Introduction: Tigecycline Evaluation and Surveillance Trail (TEST) study is an on-going global surveillance. The study was performed to determine the susceptibility of common pathogens to tigecycline and comparator antibiotics by broth microdilution (BMD) at two tertiary care centres in India from 2015 to 2017. Methodology: Total of 989 isolates collected from various clinical specimens between January 2015 and September 2017 from two centres in India were included. BMD was performed to determine the minimum inhibitory concentration (MIC) for tigecycline and comparator antibiotics. Results: Among Gram-negative bacteria, susceptibility to tigecycline was lowest among Klebsiella spp. being 84% while others such as E. coli, Enterobacter spp., Serratia spp. and H. influenzae showed susceptibility of 98%, 95%, 98% and 100% respectively. Overall, 99 isolates among Enterobacteriaceae (E. coli, Klebsiella spp. and Enterobacter spp.) were ESBL producers, susceptible to tigecycline. Among the 101 meropenem resistant Enterobacteriaceae, 85 were susceptible to tigecycline (84%). Among the Gram-positive bacteria, S. aureus and Enterococcus spp. were 99% and 98% susceptible to tigecycline respectively. Among 68 MRSA isolates in the study, 66 (97%) were susceptible to tigecycline. Seven vancomycin resistant E. faecalis were isolated and all were susceptible to tigecycline. Conclusion: Tigecycline has retained activity over both Gram-positive and Gram-negative organisms with MIC values comparable to global reports. About 98% of the MDR Gram-positive and Gram-negative bacteria in the study are susceptible to tigecycline. With increased incidence of extensively drug resistant organisms, tigecycline is a potential reserve drug.

Traditional and non-traditional methods of optimizing the functional states of public servants

The article analyzes the peculiarities of the problem of the states of human life: functional, mental and psycho-physiological. The question of the characteristics of the professional activities of civil servants and the level of stressful influences in it are discussed. Consider methods of optimizing functional states, both medical and psychological. Special attention is paid to the practices of self-regulation from transpersonal psychology, which are non-traditional for practical psychology, which, on the one hand, offer a wide range of opportunities to overcome stressful influences, and on the other, it is a potential reserve for spiritual and personal development, expansion of world view, development of creativity and internal integrity.

Potensi Cadangan Panas Bumi dengan Metoda Volumetrik Pada Sumur Saka-1 Lapangan Panas Bumi “X” Kabupaten Lembata NusaTenggara Timur

<p>Secara geologi Indonesia berada di zona Sabuk Api atau busur vulkanik yang merupakan produk konvergensi berupa subduksi antara lempeng Samudra Hindia-Australia dengan lempeng benua Asia berdasarkan konsep Tektonik lempeng. Potensi Panas bumi Indonesia tercatat sebagai yang terbesar ketiga di dunia dengan potensi cadangan 40%, Direktorat Inventarisasi Sumber Daya Mineral (ESDM) mengidentifikasi 256 daerah panas bumi dengan total potensi mencapai atau sekira 28.617 MW Penggunaan potensi panas bumi Indonesia hingga Tahun 2016 baru mencapai 4% atau sekira 1341 MW sehingga masih perlu ditingkatkan. Target pemerintah tentang kebijakan Energi Nasional terkait penggunaan energi terbarukan sebesar 25% pada tahun 2015, memicu peningkatan kegiatan pencarian dan eksplorasi panas bumi.Penyelidikan Direktorat Inventarisasi ESDM (2006) di Kabupaten Lembata, Nusa Tenggara Timur mencatat tiga lapangan potensi panas bumi yakni : Atadei, Roma dan Adum. Sumber panas bumi umumnya berasosiasi dengan gunungapi menjelang padam maupun masih aktif. Syarat terbentuknya panas bumi adalah adanya sumber panas (magma), batuan reservoir, batuan penudung dan akuifer. Hasil inventarisasi dan eksplorasi. Tulisan ini difokuskan pada perhitungan cadangan yakni energi panas bumi yang kenyataannya dapat diambil dan potensi listrik yang dapat dibangkitkan pada lapangan panas bumi X Kabupaten Lembata, Nusa Tenggara Timur. Tahapan awal dari upaya untuk mengetahui potensi energi panas bumi dimulai dari eksplorasi terencana dan terpadu yang meliputi kegiatan survey geologi, geokimia, geofisika, landaian suhu dan pemboran uji/eksplorasi panas bumi yang diakhiri dengan kegiatan pemboran sumur produksi serta pembangkit power plant untuk listrik jika hasil pemboran uji memberikan gambaran yang positif serta faktor kebutuhan akan energi/listrik.Cadangan energi panas bumi yang kenyataannya dapat diambil di Lapangan panas bumi X adalah 3,94 x 10 11 KJ dan besarnya potensi listrik yang dapat dibangkitkan adalah sebesar 41 Mwe Sehingga Lapangan panas bumi X prospek dan layak untuk dikembangkan sebagai Pembangkit Listrik Tenaga Panas Bumi (PLTP), sehingga kebutuhan listrik masyarakat Kabupaten Lembata sebesar 5 Mwe dapat terpenuhi.</p><p><em>Geologically, Indonesia is in the zone of ring of Fire or volcanic arc which is a product of convergence in the form of subduction between the Indian-Australian Ocean plate and the Asian continent plate based on the plate tectonic concept. Indonesia's geothermal potential is recorded as the third largest in the world with a potential reserve of 40%, the Directorate of Mineral Resources Inventory (ESDM) identified 256 geothermal areas with a total potential reaching or approximately 28,617 MW The use of Indonesia's geothermal potential until 2016 only reached 4% or approximately 1341 MW so that it still needs to be improved. The government's target of the National Energy policy related to the use of renewable energy by 25% in 2015, triggers an increase in geothermal exploration and exploration activities. </em><em>The investigation of the ESDM Inventory Directorate (2006) in Lembata Regency, East Nusa Tenggara recorded three geothermal potential fields namely: Atadei, Roma and Adum. Geothermal sources are generally associated with near-extinguished volcanoes or are still active. Requirements for geothermal formation are the existence of heat sources (magma), reservoir rocks, capstone and aquifers. Inventory and exploration results. This paper is focused on the calculation of reserves, namely the fact that geothermal energy can be extracted and the potential electricity that can be generated in the geothermal of X field, Lembata Regency, East Nusa Tenggara. The initial stages of the effort to determine the potential for geothermal energy starts from planned and integrated exploration which includes geological, geochemical, geophysical surveying, temperature slope and geothermal test/ exploration drilling which ends with the production well drilling and power plant for electricity if the results test drilling provides a positive picture and energy/electricity demand factors. </em><em>Reserve of geothermal energy which in fact can be taken in the geothermal field X is 3.94 x 1011 KJ and the amount of potential electricity that can be generated is 41 Mwe so that the geothermal of X field prospects and feasible to be developed as a Geothermal Power Plant (PLTP) so that the electricity needs of the Lembata Regency community of 5 MWe can be fulfilled.</em></p>

The Ways Assessment of Direct Production Electricity and Heat from Hydrogenous Fuel Based on Biogas for Autonomous Consumers

Based on the research of the fuel cell in the direct supply of hydrogen fuel with residual methane content (2-7%) confirmed the possibility of the fuel system operation in an efficient mode. The possibility of using a considerable potential "weak" biogas with a relatively low concentration of organic ingredients to produce electricity and heat in autonomous power engineering is shown. Energy potential reserve the purged fuel markedly increases with the content of methane in the original fuel and increases the role of the thermal component of the divided energy flow to about 20-26%. Integrated use of fuel energy potential with residual methane content allows to provide total effective efficiency ~ 40%. Possibility of electricity generation on the basis of complex use of organic and hydrogen fuel at creation of objects of distributive systems of power supply will approach energy sources to the consumer, having increased energy-economic indicators and efficiency of fuel use.

POTENSI DAN PERANAN PLTS SEBAGAI ENERGI ALTERNATIF MASA DEPAN DI INDONESIA

The success of national development will not be separated from the role of energy supply as a supporting facilitiy, as well as electricity. Given the potential of oil and gas energy are depleted, while coal which is abundant potential reserve but could bring a negative impact to the environment, the development of renewable energy resources for power generation is solution to achieve the national energy security. The utilization potential of solar power for electricity generation is a promising alternative, because a clean environment, unlimited resources and is available throughout the country. The tendency of diminishing the photovoltaic electricity generation cost as well as a variety of its applications to become a positive effect in the development of photovoltaic electricity generation. Integration of PLTS into the National Electrical system will require its own development strategy.