Morphological and Biochemical Parameters of Pigs’ Blood with Enzootic Pneumonia

One of the most common diseases of pigs in large pig enterprises is enzootic pneumonia. The main etiological agent causing enzootic pneumonia is Mycoplasma hyopneumoniae. Mycoplasmas have minimal virulence, but they increase the susceptibility of pigs to secondary infections. In association with other microorganisms, Mycoplasma hyopneumoniae enhances its pathogenic effect, which makes the course of the disease more severe, often leading to the death of animals. Blood tests were performed to study the changes in morphological and biochemical parameters during the development of infection caused by Mycoplasma hyopneumoniae. Experimental groups of animals were formed, consisting of healthy as well as infected and ill pigs of different ages (2, 3, and 4 months), in which the pathogen M. hyopneumoniae was detected by polymerase chain reaction. The following hematological changes were revealed in the piglets suffering from respiratory mycoplasmosis: erythropenia, leukopenia, increased blood sedimentation rate (BSR), hypoproteinemia, hypoalbuminemia, increased activity of alanine aminotransferase and alkaline phosphatase, increased urea, and hyperglycemia. Keywords: pigs breeding; pneumonia; biochemical parameters; morphological parameters

Hematology Profile Analysis and Birth Weight in Preeclampsia

Preeclampsia is a specific syndrome in pregnancy that occur after 20 weeks gestation in women who were previously normotensive. Hypertension in pregnancy caused complications in cardiovascular, hematology, endocrine, metabolic and regional blood flow accompanied by disorders of various organs, resulting in an increase of hemoconcentration in haemoglobin. The purpose of this study was to analyze the hematology profile and birth weight in preeclampsia. the design of this study was cross sectional with a sample of 40 respondents, consisting of 20 preeclampsia women and 20 women normal pregnancy. The hematology profile assessed was haemoglobin levels, hematocrit levels, platelet levels and blood sedimentation rates. The results showed haemoglobin levels, hematocrit levels, platelet level and blood sedimentation rates in both groups were not significantly difference with p value in each category was 0,110; 0,163; 0,686 and 0,983 (p value >0,05). Thus this study concludes that the hematological profile and birth weight in preeclampsia and normal pregnancies are the same.

Оптическая цифровая регистрация седиментации эритроцитов и ее моделирование в форме коллективного процесса

The dependence of the sedimentation rate of donor blood on its percentage in the sample (the degree of its dilution with physiologic saline) ranging from 0.25 to 100% (whole undiluted blood) is investigated with digital video equipment. The ratio of the value of displacement of the sediment–supernatant boundary per time unit was taken as the blood sedimentation rate. In case of registration of different speeds of movement of this boundary in a given volume of the cuvette, their spatial averaging was performed. A substantial increase in the blood sedimentation rate was found experimentally at high levels of its dilution, and, conversely, at blood concentrations in physiologic saline solutions that are close to whole blood. At the same time, the rate of blood sedimentation decreased several times with blood content in the range of 30–50%. It was experimentally shown that variation of blood content in the physiologic saline solution over a wide range did not affect the evenness of sedimentation occurring for almost any blood concentration in the mixture. In other words, in the process of sedimentation of a single blood sample of a given dilution in the physiologic saline solution, the sedimentation rate does not change with time. The experimentally obtained results allowed to build a theoretical model of blood sedimentation for two cases: 1) sedimentation of free erythrocytes (highly diluted blood) and 2) sedimentation of erythrocyte aggregates (almost undiluted blood, up to whole blood). The originality of the model comes from the proposition to consider the sedimentation of cells and/or their aggregates as a collective effect, and not in the traditional form of sedimentation of individual particles or particles interacting with each other. This model gives a satisfactory agreement with experimental laws with the use of certain empirical constants. The study is useful for understanding the process of erythrocyte sedimentation.

STUDY ABOUT THE PROGNOSIS VALUE OF HS-CRP, FIBRINOGEN, WHITE BLOOD CELL, BLOOD SEDIMENTATION RATE IN ACUTE STROKE PATIENTS

Background: The relationship between the concentration of hs-CRP, fibrinogen, white blood cells, blood sedimentation rate with prognosis in acute stroke patients. Subjects and Methods: Case-control study, cross-sectional description, over 110 cases including 66 stroke patients (44 cerebral infarction, 22 cerebral hemorrhage) and 44 cases of asthma at Hue University Hospital. Data were processing by conventional statistics methods and SPSS 15.0. Results: (i) The concentration of hs-CRP, fibrinogen in stroke patients during the acute phase was 6.74±6.61 mg/l and 4.47±0.98 g/l, higher than the control group (p<0.001). WBC was 7729±1549x109/l and VSS (K) 2455±1412 is not different from the control group with p>0.05. There was no difference between 2 groups, cerebral infarction and cerebral hemorrhage; (ii) There was a correlation between inflammatory factors on the severity of stroke patients: Positive correlation between hs-CRP levels with size of brain lesion (p=0.002; r=0.370). Inverse correlation between hs-CRP levels with glasgow scale (p=0.001; r=-0.423), inverse correlation between fibrinogen with size of brain lesion (p=0.043; r=0.250). Inverse correlation between fibrinogen concentration with glasgow scale (p=0.043; r=-0.250). Conclusion: Serum concentration of hs-CRP, fibrinogen has correlation with the severity in stroke patients during the acute phase. Key words: acute stroke, hs-CRP, fibrinogen