Structure solution of the Al69.2Cu20Cr10.8 ϕ phase

The stable ϕ phase that forms below ∼923 K around the Al69.2Cu20.0Cr10.8 composition was found to be hexagonal [P63, a = 11.045 (2), c = 12.688 (2) Å] and isostructural to the earlier reported Al6.2Cu2Re X phase [Samuha, Grushko & Meshi (2016). J. Alloys Compd. 670, 18–24]. Using the structural model of the latter, a successful Rietveld refinement of the XRD data for Al69.5Cu20.0Cr10.5 was performed. Both ϕ and X were found to be structurally related to the Al72.6Cu11.0Cr16.4 ζ phase [P63/m, a = 17.714, c = 12.591 Å; Sugiyama, Saito & Hiraga (2002). J. Alloys Compd. 342, 148–152], with a close lattice parameter c and a τ-times-larger lattice parameter a (τ is the golden mean). The structural relationship between ζ and ϕ was established on the basis of the similarity of their layered structures and common features. Additionally, the strong-reflections approach was successfully applied for the modeling of the ϕ phase based on the structural model of the ζ phase. The latter and the experimental structural model (retrieved following Rietveld refinement) were found to be essentially identical.

ACDC: Analysis of Congruent Diversification Classes

Diversification rates inferred from phylogenies are not identifiable. There are infinitely many combinations of speciation and extinction rate functions that have the exact same likelihood score for a given phylogeny, building a congruence class. The specific shape and characteristics of such congruence classes have not yet been studied. Whether speciation and extinction rate functions within a congruence class share common features is also not known. Instead of striving to make the diversification rates identifiable, we can embrace their inherent non-identifiable nature. We use two different approaches to explore a congruence class: (i) testing of specific alternative hypotheses, and (ii) randomly sampling alternative rate function within the congruence class. Our methods are implemented in the open-source R package ACDC (https://github.com/afmagee/ACDC). ACDC provides a flexible approach to explore the congruence class and provides summaries of rate functions within a congruence class. The summaries can highlight common trends, i.e. increasing, flat or decreasing rates. Although there are infinitely many equally likely diversification rate functions, these can share common features. ACDC can be used to assess if diversification rate patterns are robust despite non-identifiability. In our example, we clearly identify three phases of diversification rate changes that are common among all models in the congruence class. Thus, congruence classes are not necessarily a problem for studying historical patterns of biodiversity from phylogenies.

A systematic review on papers that study on Single Nucleotide Polymorphism that affects coronavirus 2019 severity

Background COVID-19, caused by SARS-CoV-2 has become the most threatening issue to all populations around the world. It is, directly and indirectly, affecting all of us and thus, is an emerging topic dealt in global health. To avoid the infection, various studies have been done and are still ongoing. COVID-19 cases are reported all over the globe, and among the millions of cases, genetic similarity may be seen. The genetical common features seen within confirmed cases may help outline the tendency of infection and degree severity of the disease. Here, we reviewed multiple papers on SNPs related to SARS-CoV-2 infection and analyzed their results. Methods The PubMed databases were searched for papers discussing SNPs associated with SARS-CoV-2 infection and severity. Clinical studies with human patients and statistically showing the relevance of the SNP with virus infection were included. Quality Assessment of all papers was done with Newcastle Ottawa Scale. Results In the analysis, 21 full-text literature out of 2956 screened titles and abstracts, including 63,496 cases, were included. All were human-based clinical studies, some based on certain regions gathered patient data and some based on big databases obtained online. ACE2, TMPRSS2, and IFITM3 are the genes mentioned most frequently that are related to SARS-CoV-2 infection. 20 out of 21 studies mentioned one or more of those genes. The relevant genes according to SNPs were also analyzed. rs12252-C, rs143936283, rs2285666, rs41303171, and rs35803318 are the SNPs that were mentioned at least twice in two different studies. Conclusions We found that ACE2, TMPRSS2, and IFITM3 are the major genes that are involved in SARS-CoV-2 infection. The mentioned SNPs were all related to one or more of the above-mentioned genes. There were discussions on certain SNPs that increased the infection and severity to certain groups more than the others. However, as there is limited follow-up and data due to a shortage of time history of the disease, studies may be limited.

Where are the cores in this thing? …and what are they computing?

Evolution conserves components below, and goals above, the levels for circuits and computations. This work presents evidence consistent with similar evolutionary conservation of a small, possibly canonical number of circuits and computations, and cites some historical interest in this idea. Electronic circuits are examples of what we would like to know. There are several strikingly common features of nervous systems that may be both conserved and computational essential. There is always a null hypothesis, and the work acknowledges the possibility that computation itself is ad-hoc in multiple areas and nervous systems, and not itself a conserved property. But we don’t know, and we should.

COVID-19 impact on Socio-economic and Health Interventions: A Gaps and Peaks analysis using Clustering Approach

A quantifiable model to describe the peaks and gaps during the several waves of COVID 19 is generated and applied to the progression of 120 countries. The number of waves encountered and how many more to be encountered is a question which is currently explored by all the scientific communities. In the same quest, an attempt has been made to quantitatively model the peaks and the gaps within them which have been encountered by 120 most affected countries from February 2020 to December 2021. These 120 countries were ranked based on the number of confirmed cases and deaths recorded during this period. This study further cluster these countries based on socio economic and health interventions to find an association with three dependent features of COVID 19 i.e. number of confirmed cases, deaths and death infectivity rate. The findings in this study suggests that, every wave had multiple peaks within them and as the number of peaks increased, predicting their growth rate or decline rate turns to be extremely difficult. However, considering the clusters which share the common features even with diverse countries, there is some possibility to predict what might be coming next. This study involves exhaustive analysis of reliable data which are available in open access and marks an important aspect to the COVID 19 research communities.

Green May Be Nice, but Infrastructure Is Necessary

Green infrastructure is presented as a novel and innovative approach in the current environmental planning discourse, but how new is it really? An historical overview of planning ideas in both the urban and the rural contexts indicates that the concept, if not the term, “green infrastructure” has a very long and distinguished pedigree in the field of landscape and open space planning. To determine how far the concept is indeed new, definitions of green infrastructure from the literature are examined. While “green” has long been loosely used as a synonym for natural features and vegetation in the planning context, “infrastructure” is the part of the term which is really novel. Infrastructure is otherwise understood as being either “technical” or “social”, and the common features of these otherwise very different forms are considered in order to gain a better understanding of how they might also relate to a new interpretation of green infrastructure. A number of international case studies of different “green infrastructure” projects are then presented, again to better understand their common features and potential relationship to other infrastructure types. Finally, the necessity to consider green and blue areas together and to take them as seriously as other forms of infrastructure is emphasized. The developing climate and biodiversity crises underline the urgency of implementing a flexible and multifunctional green-blue infrastructure system. This must be carefully integrated into the existing fabric of both urban and rural landscapes and will require an appropriately resourced administration and management system, reflecting its beneficial impacts.

The Early Paleolithic Go Da Site and the Bifacial Lithic Industries of Southeast Asia

The lithic industry of the stratified site Go Da in Central Vietnam is described, and its place among the contemporaneous Early Paleolithic sites of East and Southeast Asia is determined. Results of a morphological technotypological analysis of the Go Da assemblage are provided. Go Da is attributed to the An Khe-type sites situated in the eponymous area of Vietnam. Cores and tools were made from pebbles, less often from fl akes. Primary reduction focused on simple pebble cores with natural striking-platforms, whereas radial cores were less common. Predom inant among the tools are picks, scrapers of various modifi cations, choppers, and chopping tools, as well as denticulate and notched tools; also, bifaces occur. These tools belong to a single homogeneous industry, showing common features in primary reduction, preparation, and design of key artifacts. On the basis of analysis of the stratigraphic sequence of Go Da and the absolute date of 806 ± 22 ka BP, generated by the potassium-argon analysis of tektites, it is proposed that the site is older than other dated locations with the An Khe industry. Apparently, it resulted from a convergent evolution of the pebble-fl ake industry introduced by the fi rst wave of Homo erectus from Africa. Go Da and other An Khe sites likely belong to a vast habitation zone of Southeast Asian hominins with technologically and typologically similar industries dating to the boundary between the Lower and the Middle Pleistocene.

Flattening the Curve: Learning the lessons of world history to mitigate societal crises

The world is experiencing myriad crises, from global climate change to a major pandemic to runaway inequality, mass impoverishment, and rising sectarian violence. Such crises are not new, but have been recurrent features of past societies. Although these periods have typically led to massive loss of life, the failure of critical institutions, and even complete societal collapse, lessons can be learned from societies that managed to avoid the more devastating and destructive outcomes. Here, we present a preliminary analysis of outcomes from periods of crisis in 50 historical societies and examine closely four cases of averted crisis in world history, highlighting common features. A key observation is that the structural-demographic cycles that give rise to societal crises typically incorporate a ‘gilded age’ during which more future-minded governance could avert future crises. To accomplish more forward-thinking public policy, capable not just of ‘flattening the curve’, but of actually breaking the cycle that produces societal crises in the first place, we argue that systematic quantitative analysis of patterns in world history is a necessary first step.

Killing through negligence and its distinction with other kinds of murder

Problem setting. According to Art. 27 of the Constitution of Ukraine, everyone has an inalienable right to life, no one can be arbitrarily deprived of life, and the state, in turn, is obliged to protect human life. Protection of a person’s life, as a duty of the state, is manifested in the establishment of criminal liability, enshrined in Section II “Criminal offenses against life and health of a person” of the Criminal Code of Ukraine, who commit socially dangerous acts. whether there are criminal offenses and what punishments they should be committed. The distinction between crimes such as premeditated murder and negligent deprivation of another’s life is important, as criminal law theory still does not have sufficient information on this issue and does not have a complete list of features of the above crimes, but we tried to identify them in our article. Target of research. Deepening their knowledge on the caution of a person’s life due to inconsistency and drawing the line between possible offenses and conditional authority, clarifying the special characteristics of the perpetrator and the victim, outlining the essential features of the perpetrator and the victim, and researching the regulation of negligent proposal of a new version of the Criminal Code of Ukraine. Analysis of resent researches and publications. The theoretical basis for the study of the problem of murder through negligence are the works of legal scholars, in particular, M. Bazhanov, V. Borisov, S. Borodin, V. Glushkov, O. Gorokhovskaya, I. Zinchenko , V. Tyutyugin, O. Us, E. Kisilyuk, V. Kuts, M. Yefimov, S. Likhova, V. Stashis, V. Shablisty and others. Article’s main body. According to Art. 3 of the Constitution of Ukraine, man, his life and health, honor and dignity, inviolability and security are recognized in Ukraine as the highest social value. Given this constitutional provision, the legislator should pay special attention to the criminal law protection of human life and health as the most important public relations. So it is no coincidence that considering such encroachments as one of the most dangerous in the criminal law dimension, the legislator established criminal liability for their commission in Section II “Criminal offenses against life and health” of the Special Part of the Criminal Code of Ukraine. Due to the high public danger and the high prevalence of criminal offenses against human life and health, criminal law theory and law enforcement practice are under increasing scrutiny. Thus, the analysis of judicial practice in recent years shows that, for example, among all murders (Articles 117-119 of the Criminal Code of Ukraine) the number of persons convicted of deprivation of life due to negligence is about 15 percent annually. In our opinion, it is also advisable to analyze the concept of “murder” by comparing the common and distinctive features of the offenses referred to in Art. Art. 115 and 119 of the Criminal Code of Ukraine. According to scientific results, we can conclude that these offenses have many common features. It is possible to understand the common features and preconditions for the spread of these types of offenses. Conclusions and prospects for the development. A study of issues related to the criminal law analysis of murder through negligence and its difference from other types of murder, shows that these acts encroach on the identical object, which is “human life as a set of social relations.” Unfortunately, nowadays the dynamics of offenses committed in Art. Art. 115 and 119 is intensifying, so consideration of their delimitation and characterization of their features is very important. The study examines the main features of these types of crimes, as well as analyzes some provisions of national law and proposes some adjustments to them.

Structural and Semantic Analysis of English and Russian Proverbs about Marriage as a Source of Expression of Cultural and National Identity

The article is devoted to the comparative structural and semantic analysis of proverbs of the English and Russian languages with the meaning marriage. The novelty and relevance of the study consists in the fact that the proverbs that go to the heart of the current problems of marriage relations were first analyzed with the use of comparative approach in the context of structural and semantic analysis. In the course of the analysis, on the material of the proverbs of these languages, the main meanings of the proverbs were identified and systematized. The proverbs reveal the view on the value of marriage, the view on the predestination of marriage, the roles of husband and wife, controversial aspects of marital relations, as well as the question of the unity and strength of the family. An important part of the article is the study of male and female views on the problem of marriage, family life and the choice of a life partner. In English proverbs, a critical attitude towards marriage and the mention of the advantages of a bachelor life can be found more often. In Russian proverbs, marriage is generally viewed more positively but almost half of the proverbs that reveal the hardships of life in marriage are proverbs that convey a womans view of marriage. The article reveals lexical components, syntactic structures, artistic techniques and figurative means pertain to the proverbs of both linguistic and cultural ethnic groups. The presence of unique and distinctive proverbs in each language reflects the peculiarities of the historical and cultural experience of the two peoples, but the proverbs of both languages also have many common features. This is explained both by the community of human nature and knowledge, and by borrowing from common sources. Both Russian and English proverbs are characterized by using methods of comparison, contraposition, allegory, the use of personifying metaphors, lexical antonymy, the use of zoonyms, proper nouns and somatisms. In Russian, the emotional and expressive component is higher due to the use of diminutive suffixes, vernacular and vulgar words, they represent more widely archaisms and vocabulary associated with the realities of peasant life. Most Russian proverbs are composed according to the laws of the folklore genre and have a compositional completeness due to their rhythmic and phonetic design. Most of the English proverbs contain sayings, teachings, and use more abstract and neutral vocabulary, although there are also bright and original proverbs among them. The author reveals interaction of the figurative means and the conceptual component of proverbs and concludes that the linguistic means and figurative motivation of proverbs are related to the peculiarities of the national-cultural thinking of the both peoples.