Recent Advances in the Synthesis of Acyl Fluorides

Acyl fluorides are valuable intermediates in organic synthesis. They are increasingly employed in peptide synthesis, in challenging esterification and amidation reactions or in transition-metal-catalyzed transformations. This review summarizes recent advances in their preparation.1 Introduction2 Nucleophilic Fluorination2.1 α-Fluoroamine Reagents2.2 Sulfur-Based Reagents2.3 Metal Catalysts2.4 Phosphorus-Based Reagents2.5 N,N′-Dicyclohexylcarbodiimide/HF·Pyridine2.6 Uranium Hexafluoride2.7 Bromine Trifluoride3 Radical Fluorination4 Conclusion

Synthesis of Highly Deactivated Polyhalogenated Aromatic Compounds

The barium fluorobromate(III) was obtained as the product of interaction between barium fluoride and bromine(III) trifluoride. The heat of formation of Ba(BrF4)2 was found by isothermal calorimetry method. By the TG/DT analysis the thermal stability of Ba(BrF4)2 was researched. It was found that this compound is mostly stable in the atmosphere or argon up to 250 °C. It was shown that bromine trifluoride and its derive compounds with alkali and alkali-earth metals fluorides can be applied like a highly-active brominating agent in case of production of various composite materials based on polyhalogenated aromatics.