Fast digital lossy compression for X-ray ptychographic data

Increases in X-ray brightness from synchrotron light sources lead to a requirement for higher frame rates from hybrid pixel array detectors (HPADs), while also favoring charge integration over photon counting. However, transfer of the full uncompressed data will begin to constrain detector design, as well as limit the achievable continuous frame rate. Here a data compression scheme that is easy to implement in a HPAD's application-specific integrated circuit (ASIC) is described, and how different degrees of compression affect image quality in ptychography, a commonly employed coherent imaging method, is examined. Using adaptive encoding quantization, it is shown in simulations that one can digitize signals up to 16383 photons per pixel (corresponding to 14 bits of information) using only 8 or 9 bits for data transfer, with negligible effect on the reconstructed image.

Lossless Compression of Medical Image Sequences Using a Resolution Independent Predictor and Block Adaptive Encoding

The proposed block-based lossless coding technique presented in this paper targets at compression of volumetric medical images of 8-bit and 16-bit depth. The novelty of the proposed technique lies in its ability of threshold selection for prediction and optimal block size for encoding. A resolution independent gradient edge detector is used along with the block adaptive arithmetic encoding algorithm with extensive experimental tests to find a universal threshold value and optimal block size independent of image resolution and modality. Performance of the proposed technique is demonstrated and compared with benchmark lossless compression algorithms. BPP values obtained from the proposed algorithm show that it is capable of effective reduction of inter-pixel and coding redundancy. In terms of coding efficiency, the proposed technique for volumetric medical images outperforms CALIC and JPEG-LS by 0.70 % and 4.62 %, respectively.

Marked point process filter for clusterless and adaptive encoding-decoding of multiunit activity

Real-time, closed-loop experiments can uncover causal relationships between specific neural activity and behavior. An important advance in realizing this is the marked point process filtering framework which utilizes the “mark” or the waveform features of unsorted spikes, to construct a relationship between these features and behavior, which we call the encoding model. This relationship is not fixed, because learning changes coding properties of individual neurons, and electrodes can physically move during the experiment, changing waveform characteristics. We introduce a sequential, Bayesian encoding model which allows incorporation of new information on the fly to adapt the model in real time. A possible application of this framework is to the decoding of the contents of hippocampal ripples in rats exploring a maze. During physical exploration, we observe the marks and positions at which they occur, to update the encoding model, which is employed to decode contents of ripples when rats stop moving, and switch back to updating the model once the rat starts moving again.