benzoquinone ansamycin
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Total synthesis based modification of benzoquinone ansamycin antibiotics: C8 diversification of C5-C15 fragments

2019 ◽  
Vol 60 (7) ◽  
pp. 547-551 ◽  
Author(s):  
Longlong Jin ◽  
Rentao Zhang ◽  
Zhi Zhang ◽  
Chuancai Bian ◽  
Xiaoming Yu
Keyword(s):  
Total Synthesis ◽  
Benzoquinone Ansamycin

Abstract 1791: 19-Substituted benzoquinone ansamycin Hsp90 inhibitors: Effects on Hsp90 co-chaperones and Hsp90-Hsf1 complexes in cellular systems

2014 ◽  
Author(s):  
Derek A. Drechsel ◽  
Chuan-Hsin Chang ◽  
Russell Kitson ◽  
David Siegel ◽  
Christopher J. Moody ◽  
...  
Keyword(s):  
Cellular Systems ◽  
Hsp90 Inhibitors ◽  
Benzoquinone Ansamycin

scholarly journals 19-Substituted Benzoquinone Ansamycin Heat Shock Protein-90 Inhibitors: Biological Activity and Decreased Off-Target Toxicity

2014 ◽  
Vol 85 (6) ◽  
pp. 849-857 ◽  
Author(s):  
Chuan-Hsin Chang ◽  
Derek A. Drechsel ◽  
Russell R. A. Kitson ◽  
David Siegel ◽  
Qiang You ◽  
...  
Keyword(s):  
Biological Activity ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Heat Shock Protein 90 ◽  
Benzoquinone Ansamycin

Synthesis of Benzoquinone Ansamycin-Inspired Macrocyclic Lactams from Shikimic Acid

2013 ◽  
Vol 52 (18) ◽  
pp. 4800-4804 ◽  
Author(s):  
Valer Jeso ◽  
Sarah Iqbal ◽  
Pamela Hernandez ◽  
Michael D. Cameron ◽  
HaJeung Park ◽  
...  
Keyword(s):  
Shikimic Acid ◽  
Benzoquinone Ansamycin

Synthesis of Benzoquinone Ansamycin-Inspired Macrocyclic Lactams from Shikimic Acid

2013 ◽  
Vol 125 (18) ◽  
pp. 4900-4904 ◽  
Author(s):  
Valer Jeso ◽  
Sarah Iqbal ◽  
Pamela Hernandez ◽  
Michael D. Cameron ◽  
HaJeung Park ◽  
...  
Keyword(s):  
Shikimic Acid ◽  
Benzoquinone Ansamycin

Abstract B102: 19-Substituted benzoquinone ansamycins: Decreasing the toxicity of the benzoquinone ansamycin class of Hsp90 inhibitors.

2011 ◽  
Author(s):  
Chuan-Hsin Chang ◽  
Russell Kitson ◽  
Philip Reigan ◽  
David Siegel ◽  
Christopher J. Moody ◽  
...  
Keyword(s):  
Hsp90 Inhibitors ◽  
Benzoquinone Ansamycin
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