Increased decision latency in alcohol use disorder reflects altered resting-state synchrony in the anterior salience network

Increased decision latency in alcohol use disorder (AUD) has been generally explained in terms of psychomotor slowing. Recent results suggest that AUD patients’ slowed decision-making might rather reflect alterations in the neural circuitry underlying the engagement of controlled processing by salient stimuli. We addressed this hypothesis by testing a relationship between decision latency at the Cambridge Gambling Task (CGT) and intrinsic brain activity in 22 individuals with AUD and 19 matched controls. CGT deliberation time was related to two complementary facets of resting-state fMRI activity, i.e. coherence and intensity, representing early biomarkers of functional changes in the intrinsic brain architecture. For both metrics, we assessed a multiple regression (to test a relationship with deliberation time in the whole sample), and an interaction analysis (to test a significantly different relationship with decision latency across groups). AUD patients’ slowed deliberation time (p < 0.025) reflected distinct facets of altered intrinsic activity in the cingulate node of the anterior salience network previously associated with the “output” motor stage of response selection. Its heightened activity in AUD patients compared with controls, tracking choice latency (p < 0.025 corrected), might represent a compensation mechanism counterbalancing the concurrent decrease of its internal coherent activity (p < 0.025 corrected). These findings provide novel insights into the intrinsic neural mechanisms underlying increased decision latency in AUD, involving decreased temporal synchronicity in networks promoting executive control by behaviourally relevant stimuli. These results pave the way to further studies assessing more subtle facets of decision-making in AUD, and their possible changes with rehabilitative treatment.

Modeling and Integrating PV Stations into IEC 61850 XMPP Intelligent Edge Computing Gateway

Distributed energy resources (DERs) are being widely interconnected to electrical power grids. The dispersed and intermittent generational mixes bring technical and economic challenges to the power systems in terms of stability, reliability, and interoperability. In practice, most of the communication technologies in DER are provided by proprietary communication protocols, which are not designed for the prevention of cyber security over a wide area network, and methodology of DER integration is not unified. This has made it technically difficult for power utilities and aggregators to monitor and control the DER systems after they are interconnected with the electrical grids. Moreover, peer to peer communication between DER systems as well as local intelligent computation is required to reduce decision latency and enhance the stability of the smart grid or microgrid. In this paper, the first, novel architecture of IEC 61850 XMPP (extensible messaging and presence protocol) of the edge computing gateway, involving advanced concepts and technologies, was developed and completely studied to counter the abovementioned challenges. The results show that the proposed architecture can enhance the DER system’s effective integration, security in data communication and transparency for interoperability. The novel and advanced concepts involve first modeling the topology of the photovoltaic (PV) station to IEC 61850 information models according to the IEC 61850-7-4 logical nodes and the DER-specific logical nodes defined in IEC 61850-7-420. This guarantees the interoperability between DER and DER, DER and utility and DER and the energy service operator. The second step was to map the information models to IEC 61850-8-2 XMPP for the specific communication protocol in DER applications. XMPP protocol, a publish/subscribe communication mechanism, is recommended in DER applications because of its characteristics of cybersecurity and authenticated encryption. After that we enabled the edge computing capability for data processing and the analytics of the DER side for time-critical missions. The aggregated data was then sent to the control center in the cloud. By applying the edge computing architecture, the system reduced decision latency, improved data privacy and enhanced security. The goal of this paper was to introduce the practical methodologies of these novel concepts to academics and industrial engineers.

Joint Effects of Semantic Priming and Repetition in a Lexical Decision Task: Implications for a Model of Lexical Access

An experiment is reported which showed that in a lexical decision task semantic priming by a related preceding word and repetition of target words produce additive effects on decision latency. Previous models of lexical access and modifications of them are discussed, and it is argued that some such models predict an interaction of priming and repetition, while others are insufficiently precise to make a prediction. It is suggested that the generality of effects across tasks requiring lexical access must be established and the components of complex effects must be separated before an adequate model can be devised to account for the data.

Contextual Validity and the Effects of Low-Constraint Sentence Contexts on Lexical Decisions

Subjects made lexical decisions after reading either (a) low-constraint sentence contexts that did not predict the identity or meaning of congruous targets (e.g. “Mary went to her room to look at her XXXX”), or (b) control contexts that were randomly ordered lists of words. The crucial variable was the validity of the contextual information. When the sentence contexts were incongrous with the word targets as often as they were congruous (the “less-valid environment”), the congruous contexts had a slight inhibitory effect on decision latency relative to the baseline condition. In contrast, when the contexts were always congruous with the word targets (“valid environment”), they had a large facilitatory effect on decision latency. These results suggest that (a) the effects of congruous contexts can depend on the validity of the contexts across the entire experimental session, and (b) contextual facilitation may be due in part to sentence level processes.