Reversal of EPTC Induced Fatty Acid Synthesis Inhibition

EPTC (S-ethyl dipropylthiocarbamate), 1,8-naphthalic anhydride (NA),N,N-dialryl-2,2-dichloroacetamide (R-25788),CDAA(N,N-diallyl-2-chloroacetamide) and CDEC (2-chloroallyl diethyldithiocarbamate) at concentrations of 10-5M inhibited the incorporation of acetate-1-14C (Ac∗) into fatty acids of isolated spinach (Spinacia oleraceaL.) chloroplasts. Lower concentrations of these chemicals did not affect acetate incorporation into fatty acids. However, the inhibition by EPTC at 10-5M was counteracted by NA and R-25788 [agriculturally important antidotes for EPTC injury to corn (Zea maysL.)] at 10-7M.