Characterization of sexually transmitted infections and their pharmacological treatment and recurrence in a Colombian population

Introduction: Sexually transmitted infections are a public health problem worldwide. Their inadequate antimicrobial management has been associated with a higher risk of recurrence. Objective: To characterize the main sexually transmitted infections, the adherence to clinical practice guidelines in Colombia, and the factors associated with recurrence. Materials and methods: This observational study identified the main sexually transmitted infections, sociodemographic variables, and pharmacological management in a patient cohort from a population database of 6.5 million people affiliated with the Colombian Health System. A multivariate analysis was performed to identify variables associated with recurrence. Results: A total of 3158 patients were identified, with a mean age of 41.8 ± 14.5 years, and 63.1% were men. There were 4030 episodes of sexually transmitted infections, predominantly urethral syndrome (27.5%). Only 13.6% of patients with urethral syndrome, ulcerative syndrome, or genital warts were managed in compliance with clinical practice guidelines. A total of 20.6% of patients were dispensed condoms. A total of 16.7% of all patients had recurrences, and being male (OR:1.32; 95%CI:1.08-1.63), being <30 years old (OR:1.72; 95%CI:1.40-2.13), being treated in municipalities other than capital cities (OR:1.43; 95%CI:1.06-1.94), and having received inadequate treatment for the first episode (OR:1.93; 95%CI:1.52-2.39) were associated with recurrence. Conclusions: The majority of patients with sexually transmitted infections were not treated in compliance with clinical practice guidelines, and those who did not have adequate management had a higher risk of recurrence.

MANAGEMENT OF URINARY TRACT INFECTIONS

Urinary tract infection (UTI) is one of the most common pathological conditions. The positive prediction for UTI of clinical symptoms oscillates around 0.5 even lower in the case of urethral syndrome in women. An appreciable number of UTIs evolve asymptomatically, and the child under the age of 2 years the symptoms of UTI are nonspecific. The total number of germs in the urine is determined and expressed in UCF / ml. No colonies appeared after 18-24 hours of incubation, so the negative result was released (under 1000UCF / ml or under 103 CFU / ml).