premature luteinization
Recently Published Documents


TOTAL DOCUMENTS

77
(FIVE YEARS 2)

H-INDEX

21
(FIVE YEARS 0)

Reproduction ◽  
2020 ◽  
Vol 159 (1) ◽  
pp. 81-89
Author(s):  
Xiaoyan Li ◽  
Jinling Zhu ◽  
Jie Tian ◽  
Dongmei Li ◽  
Xiaodong Han ◽  
...  

Health risk of human exposure to microcystin-leucine arginine (MC-LR) has drawn more and more attention in recent years. In the present study, MC-LR inhibited miR-3473g expression of mouse granulosa cells both in vitro and in vivo. By dual-luciferase reporter assay, we confirmed miR-3473g is able to bind the 3′-UTR of StAR protein (StAR) mRNA and suppress StAR expression. Thus, downregulation of miR-3473g after MC-LR exposure led to StAR overexpression. Excessive StAR probably transported much more cholesterol into the inner membrane of the mitochondria and finally resulted in overproduction of progesterone. Our results revealed that MC-LR exposure was associated with premature luteinization of granulosa cells and may adversely affect women’s fertility.


2019 ◽  
Vol 36 (11) ◽  
pp. 2195-2206 ◽  
Author(s):  
Reda S. Hussein ◽  
Ihab Elnashar ◽  
Ahmed F. Amin ◽  
Hisham A. Abou-Taleb ◽  
Ahmed M. Abbas ◽  
...  

2019 ◽  
Vol 112 (3) ◽  
pp. e29
Author(s):  
Carlos Hernandez-Nieto ◽  
Joseph A. Lee ◽  
Tamar Alkon ◽  
Martha Luna-Rojas ◽  
Jeffrey Klein ◽  
...  

2018 ◽  
Vol 35 (10) ◽  
pp. 1723-1740 ◽  
Author(s):  
Apostolos Kaponis ◽  
Elpiniki Chronopoulou ◽  
George Decavalas

2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Yan-Guang Wu ◽  
David H. Barad ◽  
Vitaly A. Kushnir ◽  
Qi Wang ◽  
Lin Zhang ◽  
...  

2017 ◽  
Vol 34 (3) ◽  
pp. 189-191 ◽  
Author(s):  
Pieraldo Inaudi ◽  
Valeria Barra ◽  
Francesca Letizia Vellucci ◽  
Cristina Regini ◽  
Stefano Luisi

Sign in / Sign up

Export Citation Format

Share Document