Analysis of dendrimer-protein interactions and their implications on potential applications of dendrimers in nanomedicine

For the first time in literature, we show that a G5.5 PAMAM dendrimer molecule can have an effective negative or positive charge depending on environmental conditions. Control of the molecules charge enables its specific interaction with proteins.

Investigations on The Mechanism of Artificial Photosynthesis of Ca-Pc-PDI and Dendrimer Molecule by DFT Calculations

Artificial photosynthesis modelling of Ca-Pc-PDI complex Ca Phthalocyanine Perylenediimide), and dendrimer molecule using Density of Functional Theory (DFT) Method has been studied to showed the energy efficiency of these compounds in terms of electron transfer in photosynthesis. The Analysis of Ca-Pc-PDI and dendrimer compound and also chlorophyl has been done in all computations using the GAMESS-US software. The computations result in this research showed that the large wavelength complex compounds of Ca-Pc-PDI obtained was 138.3299 nm and energy efficiency obtained was 0.89 eV. The data analysis states that the absorption of harvest light energy of complex compounds Ca-Pc-PDI lies in the far UV spectrum. The other side, the polyphenylene dendrimer structure molecular orbital analyses it was found that the dendrimer was capable of electron transfers as indicated by the existence of HOMO and LUMO and result comparisons with chlorophyll. UV wavelengths of the polyethylene dendrimer and chlorophyll, respectively, suggesting that the polyphenylene dendrimer is capable of substituting chlorophyll in artificial photosyntheses. We can states from the result that these compound ability to be applied in the modeling of artificial photosynthesis as a material of energy absorption that mimics the workings of chlorophyll in terms of electron transfer in natural photosynthesis process. Keywords: Artificial photosynthesis modelling, Ca-Phthalocyanine-Perylenediimide complex, and dendrimer molecule

Correction: ATP dephosphorylation can be either enhanced or inhibited by pH-controlled interaction with a dendrimer molecule

Correction for ‘ATP dephosphorylation can be either enhanced or inhibited by pH-controlled interaction with a dendrimer molecule’ by Carla Bazzicalupi et al., Chem. Commun., 2015, 51, 3907–3910.