metabolic stability study Latest Research Papers

Development and validation of an HPLC-MS/MS method for the determination of filgotinib, a selective Janus kinase 1 inhibitor: Application to a metabolic stability study

Journal of Chromatography B ◽

10.1016/j.jchromb.2020.122195 ◽

2020 ◽

Vol 1154 ◽

pp. 122195

Author(s):

Haitham AlRabiah ◽

Adnan A. Kadi ◽

Mohamed W. Attwa ◽

Gamal A.E. Mostafa

Keyword(s):

Stability Study ◽

Metabolic Stability ◽

Janus Kinase ◽

Janus Kinase 1 ◽

Metabolic Stability Study ◽

Development And Validation

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Simultaneous quantitative determination of seven novel tyrosine kinase inhibitors in plasma by a validated UPLC-MS/MS method and its application to human microsomal metabolic stability study

Journal of Chromatography B ◽

10.1016/j.jchromb.2019.121851 ◽

2020 ◽

Vol 1136 ◽

pp. 121851 ◽

Cited By ~ 5

Author(s):

Essam Ezzeldin ◽

Muzaffar Iqbal ◽

Rasheed N. Herqash ◽

Toqa ElNahhas

Keyword(s):

Tyrosine Kinase ◽

Quantitative Determination ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Stability Study ◽

Metabolic Stability ◽

Metabolic Stability Study

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Semicarbazone Derivatives Bearing Phenyl Moiety: Synthesis, Anticancer Activity, Cell Cycle, Apoptosis-Inducing and Metabolic Stability Study

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.c18-00738 ◽

2019 ◽

Vol 67 (4) ◽

pp. 351-360 ◽

Cited By ~ 1

Author(s):

Junjie Ma ◽

Xin Ni ◽

Yali Gao ◽

Kun Huang ◽

Yu Wang ◽

...

Keyword(s):

Cell Cycle ◽

Anticancer Activity ◽

Stability Study ◽

Metabolic Stability ◽

Metabolic Stability Study ◽

Phenyl Moiety

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Development and validation of an HPLC–MS/MS method for the determination of arginine-vasopressin receptor blocker conivaptan in human plasma and rat liver microsomes: application to a metabolic stability study

Chemistry Central Journal ◽

10.1186/s13065-018-0414-5 ◽

2018 ◽

Vol 12 (1) ◽

Author(s):

Haitham Alrabiah ◽

Adnan A. Kadi ◽

Mohamed W. Attwa ◽

Gamal A. E. Mostafa

Keyword(s):

Human Plasma ◽

Rat Liver ◽

Arginine Vasopressin ◽

Liver Microsomes ◽

Stability Study ◽

Vasopressin Receptor ◽

Rat Liver Microsomes ◽

Metabolic Stability Study ◽

Development And Validation

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Determination of (4-(1,3-dioxo-1,3-dihydro-2H -isoindol- 2-yl)-N ′-[(4-ethoxyphenyl) methylidene] benzohydrazide, a novel anti-inflammatory agent, in biological fluids by UPLC-MS/MS: Assay development, validation and in vitro metabolic stability study

Biomedical Chromatography ◽

10.1002/bmc.3981 ◽

2017 ◽

Vol 31 (10) ◽

pp. e3981 ◽

Cited By ~ 2

Author(s):

Muzaffar Iqbal ◽

Mashooq A. Bhat ◽

Mohammad Raish ◽

Essam Ezzeldin

Keyword(s):

Biological Fluids ◽

Stability Study ◽

Metabolic Stability ◽

Assay Development ◽

Inflammatory Agent ◽

Anti Inflammatory ◽

Metabolic Stability Study

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A highly efficient and sensitive LC-MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study

Biomedical Chromatography ◽

10.1002/bmc.3674 ◽

2016 ◽

Vol 30 (8) ◽

pp. 1248-1255 ◽

Cited By ~ 19

Author(s):

Adnan A. Kadi ◽

Ali S. Abdelhameed ◽

Hany W. Darwish ◽

Mohamed W. Attwa ◽

Nasser S. Al-Shakliah

Keyword(s):

Human Plasma ◽

Stability Study ◽

Metabolic Stability ◽

Highly Efficient ◽

Metabolic Stability Study

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Mass Spectrometry Based Identification of Geometric Isomers during Metabolic Stability Study of a New Cytotoxic Sulfonamide Derivatives Supported by Quantitative Structure-Retention Relationships

PLoS ONE ◽

10.1371/journal.pone.0098096 ◽

2014 ◽

Vol 9 (6) ◽

pp. e98096 ◽

Cited By ~ 3

Author(s):

Mariusz Belka ◽

Weronika Hewelt-Belka ◽

Jarosław Sławiński ◽

Tomasz Bączek

Keyword(s):

Mass Spectrometry ◽

Stability Study ◽

Metabolic Stability ◽

Quantitative Structure ◽

Geometric Isomers ◽

Structure Retention ◽

Metabolic Stability Study ◽

Quantitative Structure Retention Relationships

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In vitro Metabolic Stability Study of New Cyclen Based Antimalarial Drug Leads Using RP-HPLC and LC-MS/MS

Modern Chemistry & Applications ◽

10.4172/2329-6798.1000129 ◽

2014 ◽

Vol 02 (02) ◽

Author(s):

Apoorva V Rudraraju

Keyword(s):

Antimalarial Drug ◽

Stability Study ◽

Metabolic Stability ◽

Rp Hplc ◽

Metabolic Stability Study ◽

Drug Leads

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Performance and reliability of splitless microliter gradient pumps in a metabolic stability study using cytochrome P450/3A4 and capillary liquid chromatography–mass spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2003.07.013 ◽

2003 ◽

Vol 1018 (2) ◽

pp. 203-212 ◽

Cited By ~ 4

Author(s):

Fabian Kuhn ◽

Michael Oehme ◽

Michael Schleimer

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Capillary Liquid Chromatography ◽

Stability Study ◽

Metabolic Stability ◽

Cytochrome P450 3A4 ◽

Liquid Chromatography Mass Spectrometry ◽

Metabolic Stability Study ◽

Capillary Liquid

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metabolic stability study
Recently Published Documents

TOTAL DOCUMENTS

H-INDEX

Development and validation of an HPLC-MS/MS method for the determination of filgotinib, a selective Janus kinase 1 inhibitor: Application to a metabolic stability study

Simultaneous quantitative determination of seven novel tyrosine kinase inhibitors in plasma by a validated UPLC-MS/MS method and its application to human microsomal metabolic stability study

Semicarbazone Derivatives Bearing Phenyl Moiety: Synthesis, Anticancer Activity, Cell Cycle, Apoptosis-Inducing and Metabolic Stability Study

Development and validation of an HPLC–MS/MS method for the determination of arginine-vasopressin receptor blocker conivaptan in human plasma and rat liver microsomes: application to a metabolic stability study

Determination of (4-(1,3-dioxo-1,3-dihydro-2H -isoindol- 2-yl)-N ′-[(4-ethoxyphenyl) methylidene] benzohydrazide, a novel anti-inflammatory agent, in biological fluids by UPLC-MS/MS: Assay development, validation and in vitro metabolic stability study

A highly efficient and sensitive LC-MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study

Mass Spectrometry Based Identification of Geometric Isomers during Metabolic Stability Study of a New Cytotoxic Sulfonamide Derivatives Supported by Quantitative Structure-Retention Relationships

In vitro Metabolic Stability Study of New Cyclen Based Antimalarial Drug Leads Using RP-HPLC and LC-MS/MS

Performance and reliability of splitless microliter gradient pumps in a metabolic stability study using cytochrome P450/3A4 and capillary liquid chromatography–mass spectrometry

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metabolic stability studyRecently Published Documents

TOTAL DOCUMENTS

H-INDEX

Development and validation of an HPLC-MS/MS method for the determination of filgotinib, a selective Janus kinase 1 inhibitor: Application to a metabolic stability study

Simultaneous quantitative determination of seven novel tyrosine kinase inhibitors in plasma by a validated UPLC-MS/MS method and its application to human microsomal metabolic stability study

Semicarbazone Derivatives Bearing Phenyl Moiety: Synthesis, Anticancer Activity, Cell Cycle, Apoptosis-Inducing and Metabolic Stability Study

Development and validation of an HPLC–MS/MS method for the determination of arginine-vasopressin receptor blocker conivaptan in human plasma and rat liver microsomes: application to a metabolic stability study

Determination of (4-(1,3-dioxo-1,3-dihydro-2H -isoindol- 2-yl)-N ′-[(4-ethoxyphenyl) methylidene] benzohydrazide, a novel anti-inflammatory agent, in biological fluids by UPLC-MS/MS: Assay development, validation and in vitro metabolic stability study

A highly efficient and sensitive LC-MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study

Mass Spectrometry Based Identification of Geometric Isomers during Metabolic Stability Study of a New Cytotoxic Sulfonamide Derivatives Supported by Quantitative Structure-Retention Relationships

In vitro Metabolic Stability Study of New Cyclen Based Antimalarial Drug Leads Using RP-HPLC and LC-MS/MS

Performance and reliability of splitless microliter gradient pumps in a metabolic stability study using cytochrome P450/3A4 and capillary liquid chromatography–mass spectrometry

metabolic stability study
Recently Published Documents