A COMPARATIVE ANALYSIS FOR REDUCTION OF POST-SURGICAL SORE THROAT BY APPLYING OF KETAMINE-NEBULIZATION & BETAMETHASONE-GEL OVER THE ENDO-TRACHEAL TUBE CUFF

Background: In general anaesthesia (GA), endo-tracheal -intubation is required to control respiration & to protect the airway. The commonest locations of injury while intubation are the larynx & trachea, which typically manifest as regional pain, inflammation & even necrosis. Aims & objectives: This research was carried out to contrast the efficaciousness of ketamine-nebulization & betamethasone-gel on the cuff of the endo-tracheal -tube to alleviate post-surgical throat pain (POST). Materials & methods: This is a randomized, prospective research assessing the efficaciousness of betamethasone-gel & lignocaine-jelly ketamine-nebulisation applied over the endo-tracheal -tube cuff to decrease post-surgical sore throat nebulisation (POST). The study subjects were divided randomly into ketamine (category K), betamethasone (category B) & lignocaine category (category L). Study subjects were observed immediately after extubation (0 hr), 2 hrs, 6 hrs, 12 hrs & 24 hours after the post-surgical time for POST, which was rated on a four-point ranking. Results: In this research, the total occurrence of POST was 30 %. Out of this, POST occurred only in 20 % of study subjects in the (K) category, 23 % of study subjects in the (B) category, contrasted to 47% in the (L) (control) category. The occurrence of POST at 0 hr, 2 hrs, 6 hrs, 12 hrs, 24 hours was 10 %, 10 %, 17 %, 10 % & 7 % respectively in the ketamine-nebulisation category. Conclusion: This research culminates that pre-surgical nebulization with ketamine & betamethasone-gel applied over the cuff of the endo-tracheal -tube is equally successful in reducing POST. Key Word: ketamine-nebulization, betamethasone-gel, lignocaine, Endo-tracheal -intubation