Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population

The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enrolled. The relevant data for the participants, including general information (gender, age, smoking, and drinking), comorbidities (diabetes, hypertension, and anemia), tumor-related data (tumor site, histology, degree of differentiation, and clinical stage), and treatment-related data (surgery, chemotherapy, hormones, transfusion, and peripherally inserted central venous catheter (PICC)), were collected. Statistically significant factors derived from univariate analyses were then subjected to multivariate logistic regression analyses. The results demonstrate a statistically significant difference in age, diabetes, hypertension, histology, surgery, chemotherapy, and PICC ( P < 0.05 ), compared with control. Age, diabetes, surgery, and PICC serve as independent risk factors for GC-associated thrombotic diseases ( P < 0.05 ). The present work demonstrates that GC-associated thrombotic diseases are significantly associated with age, diabetes, surgery, and PICC, suggesting a potential target for early detection and preventive strategy for GC patients with thrombophilia.

Simposio 9: Cirugía metabólica: su impacto sobre la diabetes e hígado graso

Simposio 9: El compromiso hepático en diabetes: más allá del hígadoCirugía metabólica: su impacto sobre la diabetes e hígado grasoA partir de la publicación del Diabetes Surgery Summit (DSS II) se reconoció formalmente a la cirugía gastrointestinal como terapia para la diabetes mellitus tipo 2 (DM2) asociada a obesidad, práctica que se conoce como cirugía metabólica (CM). Esta práctica se incorporó en los Estándares de Cuidado de la Diabetes de ADA en 2017. Los estudios demuestran que la manipulación quirúrgica del aparato digestivo puede ejercer efectos beneficiosos sobre la homeostasis de la glucosa, independientemente de la pérdida de peso. La cirugía mejora los niveles de glucosa en sangre con mayor eficacia que cualquier intervención en el estilo de vida y/o intervención farmacéutica, y produce remisión de la DM2 en la mayoría de los pacientes, sobre todo si se realiza la adecuada selección de los candidatos a CM.